Search Results - "Tu, Li"

Multiplexed labeling of genomic loci with dCas9 and engineered sgRNAs using CRISPRainbow by Ma, Hanhui, Tu, Li-Chun, Naseri, Ardalan, Huisman, Maximiliaan, Zhang, Shaojie, Grunwald, David, Pederson, Thoru

“…Multiple chromosomal sites are readily labeled using Cas9 and guide RNAs that bind fluorescent proteins, enabling visualization of chromatin dynamics. A lack…”
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Single-chromosome dynamics reveals locus-dependent dynamics and chromosome territory orientation by Chung, Yu-Chieh, Bisht, Madhoolika, Thuma, Jenna, Tu, Li-Chun

“…Dynamic chromatin organization instantly influences DNA accessibility through modulating local macromolecular density and interactions, driving changes in…”
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CRISPR-Sirius: RNA scaffolds for signal amplification in genome imaging by Ma, Hanhui, Tu, Li-Chun, Naseri, Ardalan, Chung, Yu-Chieh, Grunwald, David, Zhang, Shaojie, Pederson, Thoru

“…Clustered regularly interspaced short palindromic repeats (CRISPR) guide RNA scaffolds have been adapted to carry multiple binding sites for fluorescent…”
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Large cargo transport by nuclear pores: implications for the spatial organization of FG-nucleoporins by Tu, Li-Chun, Fu, Guo, Zilman, Anton, Musser, Siegfried M

“…Nuclear pore complexes (NPCs) mediate cargo traffic between the nucleus and the cytoplasm of eukaryotic cells. Nuclear transport receptors (NTRs) carry cargos…”
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Interplay of dynamic genome organization and biomolecular condensates by Chung, Yu-Chieh, Tu, Li-Chun

“…After 60 years of chromatin investigation, our understanding of chromatin organization has evolved from static chromatin fibers to dynamic nuclear…”
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Lung CSC‐derived exosomal miR‐210‐3p contributes to a pro‐metastatic phenotype in lung cancer by targeting FGFRL1 by Wang, Li, He, Jun, Hu, Haoyue, Tu, Li, Sun, Zhen, Liu, Yanyang, Luo, Feng

“…Lung cancer has the highest mortality rate among human cancers, and the majority of deaths can be attributed to metastatic spread. Lung cancer stem cells…”
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C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9–APEX2 by Gao, Xin D., Tu, Li-Chun, Mir, Aamir, Rodriguez, Tomás, Ding, Yuehe, Leszyk, John, Dekker, Job, Shaffer, Scott A., Zhu, Lihua Julie, Wolfe, Scot A., Sontheimer, Erik J.

“…Mapping proteomic composition at distinct genomic loci in living cells has been a long-standing challenge. Here we report that dCas9–APEX2 biotinylation at…”
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Pedestal subwavelength grating metamaterial waveguide ring resonator for ultra-sensitive label-free biosensing by Chang, Ching-Wen, Xu, Xiaochuan, Chakravarty, Swapnajit, Huang, Hui-Chun, Tu, Li-Wei, Chen, Quark Yungsung, Dalir, Hamed, Krainak, Michael A., Chen, Ray T.

“…Mode volume overlap factor is one of the parameters determining the sensitivity of a sensor. In past decades, many approaches have been proposed to increase…”
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MiR-497∼195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1α activity by Yang, Mi, Li, Chang-Jun, Sun, Xi, Guo, Qi, Xiao, Ye, Su, Tian, Tu, Man-Li, Peng, Hui, Lu, Qiong, Liu, Qing, He, Hong-Bo, Jiang, Tie-Jian, Lei, Min-Xiang, Wan, Mei, Cao, Xu, Luo, Xiang-Hang

“…A specific bone vessel subtype, strongly positive for CD31 and endomucin (CD31 hi Emcn hi ), is identified as coupling angiogenesis and osteogenesis. The…”
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Cell cycle- and genomic distance-dependent dynamics of a discrete chromosomal region by Ma, Hanhui, Tu, Li-Chun, Chung, Yu-Chieh, Naseri, Ardalan, Grunwald, David, Zhang, Shaojie, Pederson, Thoru

“…In contrast to the well-studied condensation and folding of chromosomes during mitosis, their dynamics during interphase are less understood. We deployed a…”
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Dietary capsaicin normalizes CGRP peptidergic DRG neurons in experimental diabetic peripheral neuropathy by Zhang, Xiao-Yi, Guo, Zheng, Li, Tu-Ping, Sun, Tao

“…Diabetic sensory neuropathy leads to impairment of peripheral sensory nerves and downregulation of calcitonin gene-related peptide (CGRP) in a functionally…”
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Ultrasound‐controlled drug release and drug activation for cancer therapy by Tu, Li, Liao, Zhihuan, Luo, Zheng, Wu, Yun‐Long, Herrmann, Andreas, Huo, Shuaidong

“…Traditional chemotherapy suffers from severe toxicity and side effects that limit its maximum application in cancer therapy. To overcome this challenge, an…”
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Periodontal disease and risk of chronic obstructive pulmonary disease: a meta-analysis of observational studies by Zeng, Xian-Tao, Tu, Ming-Li, Liu, Dong-Yan, Zheng, Dong, Zhang, Jing, Leng, WeiDong

“…Many epidemiological studies have found a positive association between periodontal disease (PD) and risk of chronic obstructive pulmonary disease (COPD), but…”
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Adiponectin as a potential therapeutic target for the treatment of restenosis by Li, Tu di, Zeng, Zhi huan

“…Restenosis is a pathologic re-narrowing of a coronary artery lesion after mechanical injury. Its pathophysiological mechanisms have not been fully elucidated…”
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A new image encryption algorithm based on optimized Lorenz chaotic system by Li, Tu, Yan, Wang, Chi, Zhang

“…Summary In this article, an improved Lorenz system was constructed, in the first stage, a nonlinear term in general Lorenz system was replaced by the sum of…”
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Tongue image quality assessment based on a deep convolutional neural network by Jiang, Tao, Hu, Xiao-Juan, Yao, Xing-Hua, Tu, Li-Ping, Huang, Jing-Bin, Ma, Xu-Xiang, Cui, Ji, Wu, Qing-Feng, Xu, Jia-Tuo

“…Tongue diagnosis is an important research field of TCM diagnostic technology modernization. The quality of tongue images is the basis for constructing a…”
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Nitrogen addition slows litter decomposition accompanied by accelerated manganese release: A five-year experiment in a subtropical evergreen broadleaf forest by Peng, Yong, Li, Yun-jie, Song, Si-yi, Chen, Yu-qin, Chen, Guan-tao, Tu, Li-hua

“…Litter decomposition is a key process for mediating ecosystem carbon (C) and nutrient cycling and is sensitive to increasing atmospheric nitrogen (N)…”
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Intracellular RNA and DNA tracking by uridine-rich internal loop tagging with fluorogenic bPNA by Liang, Yufeng, Willey, Sydney, Chung, Yu-Chieh, Lo, Yi-Meng, Miao, Shiqin, Rundell, Sarah, Tu, Li-Chun, Bong, Dennis

“…The most widely used method for intracellular RNA fluorescence labeling is MS2 labeling, which generally relies on the use of multiple protein labels targeted…”
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Accuracy of deep learning in the differential diagnosis of coronary artery stenosis: a systematic review and meta-analysis by Tu, Li, Deng, Ying, Chen, Yun, Luo, Yi

“…In recent years, as deep learning has received widespread attention in the field of heart disease, some studies have explored the potential of deep learning…”
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Influences of nitrogen addition and aboveground litter-input manipulations on soil respiration and biochemical properties in a subtropical forest by Peng, Yong, Song, Si-yi, Li, Zeng-yan, Li, Shun, Chen, Guan-tao, Hu, Hong-ling, Xie, Jiu-long, Chen, Gang, Xiao, Yin-long, Liu, Li, Tang, Yi, Tu, Li-hua

“…Atmospheric nitrogen (N) deposition has rapidly increased in subtropical ecosystems and may have altered the input of aboveground litter to soil, which…”
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