Search Results - "Tsuzaka, K"

Decreased mRNA expression of two FOXP3 isoforms in peripheral blood mononuclear cells from patients with rheumatoid arthritis and systemic lupus erythematosus by Suzuki, K, Setoyama, Y, Yoshimoto, K, Tsuzaka, K, Abe, T, Takeuchi, T

“…Both the number and functional capacity of T-regulatory (Treg) cells are known to be decreased in various autoimmune diseases. FOXP3, an essential…”
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Association of CTLA‐4 but not CD28 gene polymorphisms with systemic lupus erythematosus in the Japanese population by Ahmed, S., Ihara, K., Kanemitsu, S., Nakashima, H., Otsuka, T., Tsuzaka, K., Takeuchi, T., Hara, T.

“…Objective. Systemic lupus erythematosus (SLE) in a multisystem autoimmune disorder characterized by multiorgan pathology and autoantibodies against a variety…”
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Defective expression and tyrosine phosphorylation of the T cell receptor zeta chain in peripheral blood T cells from systemic lupus erythematosus patients by PANG, M., SETOYAMA, Y., TSUZAKA, K., YOSHIMOTO, K., AMANO, K., ABE, T., TAKEUCHI, T.

“…SUMMARY We have reported that tyrosine phosphorylation and expression of the T cell receptor zeta chain (TCR ζ) was decreased in two systemic lupus…”
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Abnormal expression and function of Fas ligand of lachrymal glands and peripheral blood in Sjögren's syndrome patients with enlarged exocrine glands by TSUBOTA, K., FUJITA, H., TADANO, K., ONODA, N., TSUZAKA, K., TAKEUCHI, T.

“…SUMMARY The objective of our study was to investigate the possibility of Fas ligand protein abnormalities in certain types of Sjögren's syndrome patients with…”
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Neurotrophic factors and neuromuscular disease: I. General comments, the neurotrophin family, and neuropoietic cytokines by Mitsumoto, Hiroshi, Tsuzaka, Kazufumi

“…Neurotrophic factors are growth factors or cytokines that are inducible polypeptides and permit intercellular communication. An explosion of information about…”
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Relationship between autoantibodies and clinical parameters in Sjögren's syndrome by Tsuzaka, K, Ogasawara, T, Tojo, T, Fujii, H, Tsukatani, Y, Kubo, A, Homma, M

“…Glandular function as estimated by salivary function scintigraphy and extraglandular manifestations were compared among 174 Sjögren's syndrome (SS) patients…”
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Complement component 9 deficiency is not a susceptibility factor for SLE by Kanemitsu, S, Ihara, K, Kira, R, Kaku, Y, Sakai, K, Tsuzaka, K, Takeuchi, T, Hara, T

“…Almost all complement component 9 (C9) deficiency in Japan shows Arg95Stop mutation of C9 gene. Therefore, we studied the prevalence of Arg95Stop mutation of…”
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Neurotrophic factor treatment in amyotrophic lateral sclerosis by Tsuzaka, K, Mitsumoto, H

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Autoantibodies to double‐stranded (ds)DNA immunoprecipitate 18S ribosomal RNA by virtue of their interaction with ribosomal protein S1 and suppress in vitro protein synthesis by TSUZAKA, K., WINKLER, T. H., KALDEN, J. R., REICHLIN, M.

“…We report that four systemic lupus erythematosus (SLE) patient sera containing anti‐dsDNA antibodies, three affinity‐purified anti‐dsDNA IgG, and a human…”
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T-cell receptor ζ mRNA with an alternatively spliced 3′ untranslated region is generated predominantly in the peripheral blood T cells of systemic lupus erythematosus patients by Tsuzaka, K., Onoda, N., Yoshimoto, K., Setoyama, Y., Suzuki, K., Pang, M., Abe, T., Takeuchi, T.

“…Abstract  To investigate the mechanism of the downregulation of T-cell receptor ζ chain (TCRζ) expression in the peripheral blood T cells (PBTs) of systemic…”
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Pulmonary pseudolymphoma presented with a mass lesion in a patient with primary Sjögren's syndrome: beneficial effect of intermittent intravenous cyclophosphamide by Tsuzaka, K, Akama, H, Yamada, H, Akizuki, M, Tojo, T, Homma, M

“…A 61-year-old woman with primary Sjögren's syndrome (SS) presented with fever, dry cough, dyspnea on exertion, and a mass lesion with reticular shadowing at…”
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Systemic lupus erythematosus by Takeuchi, T, Tsuzaka, K, Abe, T

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Nonprecipitating IgG or IgM anti-Sm antibody: clinical significance and changes in immunoglobulin class by Tsuzaka, K, Ogasawara, T, Tojo, T, Mimori, T, Satoh, M, Homma, M

“…To estimate the clinical significance of IgG or IgM nonprecipitating anti-Sm antibodies and their immunoglobulin (Ig) class switch. Ninety-one sera which were…”
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IgG4-positive multi-organ lymphoproliferative syndrome manifesting as chronic symmetrical sclerosing dacryo-sialadenitis with subsequent secondary portal hypertension and remarkable IgG4-linked IL-4 elevation by Suzuki, Katsuya, Tamaru, Jun-ichi, Okuyama, Ayumi, Kameda, Hideto, Amano, Koichi, Nagasawa, Hayato, Nishi, Eiko, Yoshimoto, Keiko, Setoyama, Yumiko, Kaneko, Keiko, Osada, Hisato, Honda, Norinari, Sasaki, Yasutsuna, Itoyama, Shinji, Tsuzaka, Kensei, Takeuchi, Tsutomu

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A case with rheumatoid arthritis complicated with ANCA-associated vasculitis by Amano, K, Nakabayashi, K, Tsuzaka, K, Takeuchi, T, Koide, J, Abe, T, Matsumura, O

“…A 50-year-old woman with rheumatoid arthritis (RA) developed constitutive symptoms such as fever and weight loss, mononeuritis multiplex and rapidly…”
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Mikulicz's Disease and Sjogren's Syndrome by Tsubota, Kazuo, Fujita, Hiromi, Tsuzaka, Kensei, Takeuchi, Tsutomu

“…To characterize lacrimal gland function and lymphocyte infiltration in patients with Mikulicz's disease (MD) and Sjögren's syndrome (SS). Four patients with MD…”
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Portal and pulmonary hypertension in a patient with MCTD by Sekiguchi, Y, Amano, K, Takano, Y, Saito, K, Itoh, I, Tsuzaka, K, Abe, T, Takeuchi, T

“…A 42-year-old woman with mixed connective tissue disease (MCTD) died due to the rupture of esophageal varices. The autopsy revealed fresh thrombi in the main…”
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TCR zeta mRNA with an alternatively spliced 3'-untranslated region detected in systemic lupus erythematosus patients leads to the down-regulation of TCR zeta and TCR/CD3 complex by Tsuzaka, Kensei, Fukuhara, Izumi, Setoyama, Yumiko, Yoshimoto, Keiko, Suzuki, Katsuya, Abe, Tohru, Takeuchi, Tsutomu

“…The reduction or absence of TCR zeta-chain (zeta) expression in systemic lupus erythematosus (SLE) patients is thought to be related to the pathogenesis of…”
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A splice variant of the TCR zeta mRNA lacking exon 7 leads to the down-regulation of TCR zeta, the TCR/CD3 complex, and IL-2 production in systemic lupus erythematosus T cells by Tsuzaka, Kensei, Setoyama, Yumiko, Yoshimoto, Keiko, Shiraishi, Kiyono, Suzuki, Katsuya, Abe, Tohru, Takeuchi, Tsutomu

“…The reduction or absence of TCR zeta-chain (zeta) expression in patients with systemic lupus erythematosus (SLE) is thought to be a factor in the pathogenesis…”
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A case of primary intracranial malignant lymphoma presenting opsoclonus-polymyoclonia syndrome by Tsuzaka, K, Aimoto, Y, Minami, N, Moriwaka, F, Tashiro, K

“…A 46-year-old woman was doing well until December 1989, when she noted vertigo and difficulty in walking. She was admitted to our department on February, 7,…”
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