Search Results - "Tsuyoshi Yamada"
-
1
Aryl Boronic Esters Are Stable on Silica Gel and Reactive under Suzuki–Miyaura Coupling Conditions
Published in Organic letters (20-05-2022)“…A wide range of aryl boronic 1,1,2,2-tetraethylethylene glycol esters [ArB(Epin)s] were readily synthesized. Purifying aryl boronic esters by conventional…”
Get full text
Journal Article -
2
Terbinafine Resistance of Trichophyton Clinical Isolates Caused by Specific Point Mutations in the Squalene Epoxidase Gene
Published in Antimicrobial agents and chemotherapy (01-07-2017)“…Terbinafine is one of the allylamine antifungal agents whose target is squalene epoxidase (SQLE). This agent has been extensively used in the therapy of…”
Get full text
Journal Article -
3
Trichophyton rubrum Azole Resistance Mediated by a New ABC Transporter, TruMDR3
Published in Antimicrobial agents and chemotherapy (01-11-2019)“…The mechanisms of terbinafine resistance in a set of clinical isolates of have been studied recently. Of these isolates, TIMM20092 also showed reduced…”
Get full text
Journal Article -
4
New Gateways to the Platinum Group Metal-Catalyzed Direct Deuterium-Labeling Method Utilizing Hydrogen as a Catalyst Activator
Published in Chemical & pharmaceutical bulletin (01-01-2018)“…Deuterium-labeled compounds are widely utilized in various scientific fields. We summarize the recent advances in the direct deuteration of sugar, saturated…”
Get full text
Journal Article -
5
Development of an efficient gene-targeting system for elucidating infection mechanisms of the fungal pathogen Trichosporon asahii
Published in Scientific reports (14-09-2021)“…Trichosporon asahii is a pathogenic fungus that causes severe, deep-seated fungal infections in neutropenic patients . Elucidating the infection mechanisms of…”
Get full text
Journal Article -
6
Ruthenium-on-Carbon-Catalyzed Facile Solvent-Free Oxidation of Alcohols: Efficient Progress under Solid–Solid (Liquid)–Gas Conditions
Published in Chemical & pharmaceutical bulletin (01-12-2021)“…A protocol for the ruthenium-on-carbon (Ru/C)-catalyzed solvent-free oxidation of alcohols, which proceeds efficiently under solid–solid (liquid)–gas…”
Get full text
Journal Article -
7
Establishment of a gene recombination method for a major human skin commensal fungus, Malassezia restricta , using Agrobacterium tumefaciens -mediated gene transfer system
Published in Medical mycology (Oxford) (30-11-2022)“…Abstract Malassezia restricta is the most predominant fungus in the microbiome of human skin. This microorganism can cause or exacerbate Malassezia-associated…”
Get full text
Journal Article -
8
Innovative next-generation monoclonal antibody purification using activated carbon: A challenge for flow-through and column-free processes
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-07-2019)“…Activated carbon (AC) is a porous solid with a larger surface area and lower cost than chromatography resins. AC has been used in the field of…”
Get full text
Journal Article -
9
Keratin Degradation by Dermatophytes Relies on Cysteine Dioxygenase and a Sulfite Efflux Pump
Published in Journal of investigative dermatology (01-06-2013)“…Millions of people suffer from superficial infections caused by dermatophytes. Intriguingly, these filamentous fungi exclusively infect keratin-rich host…”
Get full text
Journal Article -
10
Slope-induced factors shape bacterial communities in surface soils in a forested headwater catchment
Published in Catena (Giessen) (01-07-2022)“…•We examined soil bacterial communities across a forested headwater catchment.•Soil bacterial communities showed rapid turnover along slopes.•Slope-induced…”
Get full text
Journal Article -
11
Purification of monoclonal antibodies entirely in flow-through mode
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-09-2017)“…•An antibody purification process entirely in flow-through mode was achieved.•Buffer exchange improved the impurity clearance by depth filtration.•A…”
Get full text
Journal Article -
12
A critical role of calcineurin in stress responses, hyphal formation, and virulence of the pathogenic fungus Trichosporon asahii
Published in Scientific reports (27-09-2022)“…Trichosporon asahii is a conditional pathogenic fungus that causes severe and sometimes fatal infections in immunocompromised patients. While calcineurin, an…”
Get full text
Journal Article -
13
Floor Cover Percentage Determines Splash Erosion in Chamaecyparis obtusa Forests
Published in Soil Science Society of America journal (01-11-2015)“…Plantations of Chamaecyparis obtusa (Siebold & Zucc.) Endl. are susceptible to soil erosion following significant decreases in forest floor cover. We…”
Get full text
Journal Article -
14
Tacrolimus inhibits stress responses and hyphal formation via the calcineurin signaling pathway in Trichosporon asahii
Published in Microbiology and immunology (01-02-2023)“…The pathogenic fungus Trichosporon asahii causes fatal deep‐seated mycosis in immunocompromised patients. Calcineurin, which is widely conserved in eukaryotes,…”
Get full text
Journal Article -
15
An efficient gene targeting system using Δku80 and functional analysis of Cyp51A in Trichophyton rubrum
Published in AMB Express (31-08-2024)“…Trichophyton rubrum is one of the most frequently isolated fungi in patients with dermatophytosis. Despite its clinical significance, the molecular mechanisms…”
Get full text
Journal Article -
16
Continuous‐Flow Suzuki‐Miyaura and Mizoroki‐Heck Reactions under Microwave Heating Conditions
Published in Chemical record (01-01-2019)“…Microwave‐assisted continuous‐flow reactions have attracted significant interest from synthetic organic chemists, especially process chemists from practical…”
Get full text
Journal Article -
17
A novel silkworm infection model with fluorescence imaging using transgenic Trichosporon asahii expressing eGFP
Published in Scientific reports (03-07-2020)“…Trichosporon asahii is a pathogenic fungus that causes deep mycosis in patients with neutropenia. Establishing an experimental animal model for quantitatively…”
Get full text
Journal Article -
18
An invertebrate infection model for evaluating anti-fungal agents against dermatophytosis
Published in Scientific reports (25-09-2017)“…Animal models of pathogenic infection are needed to evaluate candidate compounds for the development of anti-infectious drugs. Dermatophytes are pathogenic…”
Get full text
Journal Article -
19
Designing a Model Predictive Controller for Displacement Control of Axial Piston Pump
Published in International journal of automation technology (05-01-2024)“…Variable displacement hydraulic pumps are widely used for energy efficiency, and they often have a mechanical feedback mechanism to ensure target tracking…”
Get full text
Journal Article -
20
Pt/CB-Catalyzed Chemoselective Hydrogenation Using In Situ-Generated Hydrogen by Microwave-Mediated Dehydrogenation of Methylcyclohexane under Continuous-Flow Conditions
Published in Catalysts (01-06-2024)“…Hydrogen gas (H2) has attracted attention as a next-generation clean energy source. Its efficient and safe preparation and utilization are crucial in both the…”
Get full text
Journal Article