Search Results - "Tsuruzoe, Kaku"
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Adenosine Monophosphate-Activated Protein Kinase Suppresses Vascular Smooth Muscle Cell Proliferation Through the Inhibition of Cell Cycle Progression
Published in Circulation research (14-10-2005)“…Vascular smooth muscle cell (VSMC) proliferation is a critical event in the development and progression of vascular diseases, including atherosclerosis. We…”
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Impact of Mitochondrial Reactive Oxygen Species and Apoptosis Signal–Regulating Kinase 1 on Insulin Signaling
Published in Diabetes (New York, N.Y.) (01-05-2006)“…Impact of Mitochondrial Reactive Oxygen Species and Apoptosis Signal–Regulating Kinase 1 on Insulin Signaling Koujiro Imoto 1 , Daisuke Kukidome 1 , Takeshi…”
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An acylic polyisoprenoid derivative, geranylgeranylacetone protects against visceral adiposity and insulin resistance in high-fat-fed mice
Published in American journal of physiology: endocrinology and metabolism (01-11-2010)“…Induction of heat shock protein (HSP)72 improves insulin resistance and obesity in diabetic animal models. Geranylgeranylacetone (GGA), known as an antiulcer…”
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Endothelial MnSOD overexpression prevents retinal VEGF expression in diabetic mice
Published in Biochemical and biophysical research communications (15-02-2008)“…We previously proposed that hyperglycemia-induced mitochondrial ROS overproduction is a key event in the development of diabetic complications. In this study,…”
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A Case of Ectopic Adrenocorticotropic Hormone-producing Pancreatic Neuroendocrine Tumor with Multiple Liver Metastases
Published in Endocrine Journal (2010)“…Ectopic adrenocorticotropic hormone (ACTH) production by the pancreatic neuroendocrine tumor (p-NET) is relatively rare, and patients with this tumor show poor…”
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Effects of Olmesartan, an Angiotensin II Receptor Blocker, on Peripheral Insulin Sensitivity in Japanese Subjects with Type 2 Diabetes and Hypertension
Published in Internal Medicine (01-01-2012)“…Objective Several studies have assessed the efficacy of angiotensin receptor blockers (ARBs) on peripheral insulin sensitivity using the euglycemic…”
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The impact of Ca2+/calmodulin-dependent protein kinase II on insulin gene expression in MIN6 cells
Published in Biochemical and biophysical research communications (18-05-2012)“…► Insulin gene promoter activity is downregulated by CaMKIIδ2 in MIN6 cells. ► The effects of CaMKIIδ2 are independent of glucose and membrane depolarization…”
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Coexistence of resistance to thyroid hormone and papillary thyroid carcinoma
Published in Endocrinology, diabetes & metabolism case reports (01-05-2016)“…Summary Resistance to thyroid hormone (RTH) is a syndrome of reduced tissue responsiveness to thyroid hormones. RTH is majorly caused by mutations in the…”
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Insulin Receptor Substrate 3 (IRS-3) and IRS-4 Impair IRS-1- and IRS-2-Mediated Signaling
Published in Molecular and Cellular Biology (01-01-2001)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells
Published in Biochemical and biophysical research communications (11-03-2005)“…The liver is one of the major target organs of insulin in which the expression of insulin receptor is abundant. We analyzed the effect of AICAR, an AMPK…”
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Type A or type B syndrome of insulin resistance
Published in Nihon rinshō (28-09-2006)Get more information
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Creation and characterization of a mitochondrial DNA-depleted pancreatic beta-cell line: impaired insulin secretion induced by glucose, leucine, and sulfonylureas
Published in Diabetes (New York, N.Y.) (01-04-1998)“…Creation and characterization of a mitochondrial DNA-depleted pancreatic beta-cell line: impaired insulin secretion induced by glucose, leucine, and…”
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Polymorphisms in insulin receptor substrate-1 (IRS-1) gene
Published in Nihon rinshō (01-07-2002)Get more information
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Possible Involvement of Atypical Protein Kinase C (PKC) in Glucose-Sensitive Expression of the Human Insulin Gene: DNA-Binding Activity and Transcriptional Activity of Pancreatic and Duodenal Homeobox Gene-1 (PDX-1) Are Enhanced via Calphostin C-Sensitive but Phorbol 12-Myristate 13-Acetate (PMA) and Gö 6976-Insensitive Pathway
Published in ENDOCRINE JOURNAL (01-02-1999)“…Pancreatic and duodenal homeobox gene-1(PDX-1) is a transcription factor which regulates the insulin gene expression. In this study, we tried to elucidate the…”
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A Case of Ectopic Adrenocorticotropic Hormone-producing Pancreatic Neuroendocrine Tumor with Multiple Liver Metastases
Published in ENDOCRINE JOURNAL (2010)“…Abstract. Ectopic adrenocorticotropic hormone (ACTH) production by the pancreatic neuroendocrine tumor (p-NET) is relatively rare, and patients with this tumor…”
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Polymorphisms of PPARs and metabolic disorders
Published in Nihon rinshō (01-04-2005)“…Peroxisome proliferator-activated receptors (PPARs) are a member of transcriptional factor that regulates expression of several genes associated with glucose…”
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Cell-specific regulation of IRS-1 gene expression: Role of E box and C/EBP binding site in HepG2 cells and CHO cells
Published in Diabetes (New York, N.Y.) (01-03-1997)“…Insulin receptor substrate 1 (IRS-1) is one of the major substrates of insulin receptor tyrosine kinase and mediates multiple insulin signals downstream. We…”
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Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice
Published in Biochemical and biophysical research communications (07-01-2011)“…► Caloric restriction (CR) reduced the weight of ob/ob mice. ► CR reduced ER stress markers such as phosphorylated PERK and eIF2α in ob/ob mice. ► CR reduced…”
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Oxidized Low Density Lipoprotein Activates Peroxisome Proliferator-activated Receptor-α (PPARα) and PPARγ through MAPK-dependent COX-2 Expression in Macrophages
Published in The Journal of biological chemistry (11-04-2008)“…It has been reported that oxidized low density lipoprotein (Ox-LDL) can activate both peroxisome proliferator-activated receptor-α (PPARα) and PPARγ. However,…”
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