Search Results - "Tsuruta, Hiro"

Prion Protein—Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering by Carter, Lester, Kim, Seung Joong, Schneidman-Duhovny, Dina, Stöhr, Jan, Poncet-Montange, Guillaume, Weiss, Thomas M., Tsuruta, Hiro, Prusiner, Stanley B., Sali, Andrej

“…Aberrant self-assembly, induced by structural misfolding of the prion proteins, leads to a number of neurodegenerative disorders. In particular, misfolding of…”
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Integrative Structure–Function Mapping of the Nucleoporin Nup133 Suggests a Conserved Mechanism for Membrane Anchoring of the Nuclear Pore Complex by Kim, Seung Joong, Fernandez-Martinez, Javier, Sampathkumar, Parthasarathy, Martel, Anne, Matsui, Tsutomu, Tsuruta, Hiro, Weiss, Thomas M., Shi, Yi, Markina-Inarrairaegui, Ane, Bonanno, Jeffery B., Sauder, J. Michael, Burley, Stephen K., Chait, Brian T., Almo, Steven C., Rout, Michael P., Sali, Andrej

“…The nuclear pore complex (NPC) is the sole passageway for the transport of macromolecules across the nuclear envelope. Nup133, a major component in the…”
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The origin of the electrostatic perturbation in acetoacetate decarboxylase by Ho, Meng-Chiao, Ménétret, Jean-François, Tsuruta, Hiro, Allen, Karen N.

“…Acetoacetate decarboxylase (AADase) has long been cited as the prototypical example of the marked shifts in the p K a values of ionizable groups that can occur…”
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Small angle X-ray scattering as a complementary tool for high-throughput structural studies by Grant, Thomas D., Luft, Joseph R., Wolfley, Jennifer R., Tsuruta, Hiro, Martel, Anne, Montelione, Gaetano T., Snell, Edward H.

“…Structural crystallography and nuclear magnetic resonance (NMR) spectroscopy are the predominant techniques for understanding the biological world on a…”
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Topologically Linked Protein Rings in the Bacteriophage HK97 Capsid by Wikoff, William R., Liljas, Lars, Duda, Robert L., Tsuruta, Hiro, Hendrix, Roger W., Johnson, John E.

“…The crystal structure of the double-stranded DNA bacteriophage HK97 mature empty capsid was determined at 3.6 angstrom resolution. The 660 angstrom diameter…”
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Ni(II) coordination to mixed sites modulates DNA binding of HpNikR via a long-range effect by West, Abby L, Evans, Sarah E, González, Javier M, Carter, Lester G, Tsuruta, Hiro, Pozharski, Edwin, Michel, Sarah L. J

“…Helicobacter pylori NikR (HpNikR) is a nickel-dependent transcription factor that regulates multiple genes in the H. pylori pathogen. There are conflicting…”
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Crystal and Solution Structures of an HslUV Protease–Chaperone Complex by Sousa, Marcelo C., Trame, Christine B., Tsuruta, Hiro, Wilbanks, Sigurd M., Reddy, Vijay S., McKay, David B.

“…HslUV is a “prokaryotic proteasome” composed of the HslV protease and the HslU ATPase, a chaperone of the Clp/Hsp100 family. The 3.4 Å crystal structure of an…”
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Trapping and structure determination of an intermediate in the allosteric transition of aspartate transcarbamoylase by Guo, Wenyue, West, Jay M, Dutton, Andrew S, Tsuruta, Hiro, Kantrowitz, Evan R

“…X-ray crystallography and small-angle X-ray scattering (SAXS) in solution have been used to show that a mutant aspartate transcarbamoylase exists in an…”
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Structure and mechanism of the RuvB holliday junction branch migration motor by Putnam, Christopher D, Clancy, Sheila B, Tsuruta, Hiro, Gonzalez, Susana, Wetmur, James G, Tainer, John A

“…The RuvB hexamer is the chemomechanical motor of the RuvAB complex that migrates Holliday junction branch-points in DNA recombination and the rescue of stalled…”
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Structures of the signal recognition particle receptor from the archaeon Pyrococcus furiosus: implications for the targeting step at the membrane by Egea, Pascal F, Tsuruta, Hiro, de Leon, Gladys P, Napetschnig, Johanna, Walter, Peter, Stroud, Robert M

“…In all organisms, a ribonucleoprotein called the signal recognition particle (SRP) and its receptor (SR) target nascent proteins from the ribosome to the…”
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A Fluorescent Probe-labeled Escherichia coli Aspartate Transcarbamoylase That Monitors the Allosteric Conformational State by West, Jay M., Tsuruta, Hiro, Kantrowitz, Evan R.

“…A new system has been developed capable of monitoring conformational changes of the 240s loop of aspartate transcarbamoylase, which are tightly correlated with…”
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Importance of Domain Closure for the Catalysis and Regulation ofEscherichia coli Aspartate Transcarbamoylase by Macol, Christine P., Tsuruta, Hiro, Kantrowitz, Evan R.

“…Two hybrid versions ofEscherichia coli aspartate transcarbamoylase were studied to determine the influence of domain closure on the homotropic and heterotropic…”
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Tetrameric Assembly of Full-Sequence Protein Zero Myelin Glycoprotein by Synchrotron X-Ray Scattering by Inouye, Hideyo, Tsuruta, Hiro, Sedzik, Jan, Uyemura, Keiichi, Kirschner, Daniel A.

“…Highly purified myelin P0 glycoprotein was solubilized to 1–8 mg/ml in 0.1% sodium dodecyl sulfate (SDS), and the solution structure of the P0 assembly was…”
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Stabilization of the R Allosteric Structure of Escherichia coli Aspartate Transcarbamoylase by Disulfide Bond Formation by West, Jay M., Tsuruta, Hiro, Kantrowitz, Evan R.

“…Here we report the first use of disulfide bond formation to stabilize the R allosteric structure of Escherichia coli aspartate transcarbamoylase. In the R…”
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240s Loop Interactions Stabilize the T State of Escherichia coli Aspartate Transcarbamoylase by Alam, Neelima, Stieglitz, Kimberly A., Caban, Michael D., Gourinath, Samudrala, Tsuruta, Hiro, Kantrowitz, Evan R.

“…Here the functional and structural importance of interactions involving the 240s loop of the catalytic chain for the stabilization of the T state of aspartate…”
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Solution X-Ray Scattering-Based Estimation of Electron Cryomicroscopy Imaging Parameters for Reconstruction of Virus Particles by Thuman-Commike, Pamela A., Tsuruta, Hiro, Greene, Barrie, Prevelige, Peter E., King, Jonathan, Chiu, Wah

“…Structure factor amplitudes and phases can be computed directly from electron cryomicroscopy images. Inherent aberrations of the electromagnetic lenses and…”
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An integrated high-throughput data acquisition system for biological solution X-ray scattering studies by Martel, Anne, Liu, Ping, Weiss, Thomas M., Niebuhr, Marc, Tsuruta, Hiro

“…A fully automated high‐throughput solution X‐ray scattering data collection system has been developed for protein structure studies at beamline 4‐2 of the…”
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The Role of Intersubunit Interactions for the Stabilization of the T State of Escherichia coli Aspartate Transcarbamoylase by Chan, Robin S., Sakash, Jessica B., Macol, Christine P., West, Jay M., Tsuruta, Hiro, Kantrowitz, Evan R.

“…Homotropic cooperativity in Escherichia coli aspartate transcarbamoylase results from the substrate-induced transition from the T to the R state. These two…”
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Domain Bridging Interactions by Sakash, Jessica B., Williams, Mark K., Tsuruta, Hiro, Kantrowitz, Evan R.

“…Aspartate transcarbamoylase undergoes a domain closure in the catalytic chains upon binding of the substrates that initiates the allosteric transition…”
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Balanced Electrostatic and Structural Forces Guide the Large Conformational Change Associated with Maturation of T = 4 Virus by Matsui, Tsutomu, Tsuruta, Hiro, Johnson, John E.

“…Nudaurelia capensis omega virus has a well-characterized T = 4 capsid that undergoes a pH-dependent large conformational changes (LCC) and associated…”
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