Search Results - "Tsuruga, Tetsushi"

Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1 by Au Yeung, Chi Lam, Co, Ngai-Na, Tsuruga, Tetsushi, Yeung, Tsz-Lun, Kwan, Suet-Ying, Leung, Cecilia S., Li, Yong, Lu, Edward S., Kwan, Kenny, Wong, Kwong-Kwok, Schmandt, Rosemarie, Lu, Karen H., Mok, Samuel C.

“…Advanced ovarian cancer usually spreads to the visceral adipose tissue of the omentum. However, the omental stromal cell-derived molecular determinants that…”
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Application of artificial intelligence in gynecologic malignancies: A review by Sone, Kenbun, Toyohara, Yusuke, Taguchi, Ayumi, Miyamoto, Yuichiro, Tanikawa, Michihiro, Uchino‐Mori, Mayuyo, Iriyama, Takayuki, Tsuruga, Tetsushi, Osuga, Yutaka

“…With the development of machine learning and deep learning models, artificial intelligence is now being applied to the field of medicine. In oncology, the use…”
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Targeting Epigenetic Regulators for Endometrial Cancer Therapy: Its Molecular Biology and Potential Clinical Applications by Inoue, Futaba, Sone, Kenbun, Toyohara, Yusuke, Takahashi, Yu, Kukita, Asako, Hara, Aki, Taguchi, Ayumi, Tanikawa, Michihiro, Tsuruga, Tetsushi, Osuga, Yutaka

“…Endometrial cancer is one of the most frequently diagnosed gynecological malignancies worldwide. However, its prognosis in advanced stages is poor, and there…”
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Automated system for diagnosing endometrial cancer by adopting deep-learning technology in hysteroscopy by Takahashi, Yu, Sone, Kenbun, Noda, Katsuhiko, Yoshida, Kaname, Toyohara, Yusuke, Kato, Kosuke, Inoue, Futaba, Kukita, Asako, Taguchi, Ayumi, Nishida, Haruka, Miyamoto, Yuichiro, Tanikawa, Michihiro, Tsuruga, Tetsushi, Iriyama, Takayuki, Nagasaka, Kazunori, Matsumoto, Yoko, Hirota, Yasushi, Hiraike-Wada, Osamu, Oda, Katsutoshi, Maruyama, Masanori, Osuga, Yutaka, Fujii, Tomoyuki

“…Endometrial cancer is a ubiquitous gynecological disease with increasing global incidence. Therefore, despite the lack of an established screening technique to…”
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A low preoperative albumin-to-globulin ratio is a negative prognostic factor in patients with surgically treated cervical cancer by Kawata, Akira, Taguchi, Ayumi, Baba, Satoshi, Miyamoto, Yuichiro, Tanikawa, Michihiro, Sone, Kenbun, Tsuruga, Tetsushi, Mori, Mayuyo, Oda, Katsutoshi, Kawana, Kei, Osuga, Yutaka, Fujii, Tomoyuki

“…Background The albumin-to-globulin ratio reflects both the nutrition and inflammation and predicts prognosis in patients with various malignancies. However, in…”
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Characterization of a fluorescence imaging probe that exploits metabolic dependency of ovarian clear cell carcinoma by Tsuchimochi, Saki, Wada-Hiraike, Osamu, Urano, Yasuteru, Kukita, Asako, Yamaguchi, Kohei, Honjo, Harunori, Taguchi, Ayumi, Tanikawa, Michihiro, Sone, Kenbun, Mori-Uchino, Mayuyo, Tsuruga, Tetsushi, Oda, Katsutoshi, Osuga, Yutaka

“…The purpose of this study is to clarify the metabolic dependence of ovarian clear cell carcinoma (CCC) by comparing normal tissues and to examine the…”
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ASK1 promotes uterine inflammation leading to pathological preterm birth by Yoshikawa, Midori, Iriyama, Takayuki, Suzuki, Kensuke, Sayama, Seisuke, Tsuruga, Tetsushi, Kumasawa, Keiichi, Nagamatsu, Takeshi, Homma, Kengo, Naguro, Isao, Osuga, Yutaka, Ichijo, Hidenori, Fujii, Tomoyuki

“…It is widely accepted that enhanced uterine inflammation associated with microbial infection is a main causative factor for preterm birth. However, little is…”
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Interleukin‐17 is associated with expression of programmed cell death 1 ligand 1 in ovarian carcinoma by Aotsuka, Aeri, Matsumoto, Yoko, Arimoto, Takahide, Kawata, Akira, Ogishima, Juri, Taguchi, Ayumi, Tanikawa, Michihiro, Sone, Kenbun, Mori‐Uchino, Mayuyo, Tsuruga, Tetsushi, Oda, Katsutoshi, Kawana, Kei, Osuga, Yutaka, Fujii, Tomoyuki

“…The programmed cell death 1/programmed cell death 1 ligand 1 pathway was successfully targeted in cancer immunotherapy. Elevated interleukin‐17 (IL‐17), which…”
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Histone arginine methyltransferase CARM1 selective inhibitor TP-064 induces apoptosis in endometrial cancer by Inoue, Futaba, Sone, Kenbun, Toyohara, Yusuke, Tanimoto, Saki, Takahashi, Yu, Kusakabe, Misako, Kukita, Asako, Honjoh, Harunori, Nishijima, Akira, Taguchi, Ayumi, Miyamoto, Yuichiro, Tanikawa, Michihiro, Iriyama, Takayuki, Uchino, Mayuyo-mori, Tsuruga, Tetsushi, Wada-Hiraike, Osamu, Oda, Katsutoshi, Osuga, Yutaka

“…Histone modification is the key epigenetic mechanism that regulates gene expression. Coactivator-associated arginine methyltransferase 1 (CARM1) is an arginine…”
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Production of an anti-angiogenic factor sFLT1 is suppressed via promoter hypermethylation of FLT1 gene in choriocarcinoma cells by Sasagawa, Tadashi, Jinno-Oue, Atsushi, Nagamatsu, Takeshi, Morita, Kazuki, Tsuruga, Tetsushi, Mori-Uchino, Mayuyo, Fujii, Tomoyuki, Shibuya, Masabumi

“…Soluble Fms-like tyrosine kinase-1 (sFLT1) as an anti-angiogenic factor is abundantly expressed in placental trophoblasts. Choriocarcinoma, a malignant tumor…”
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Prognosis of high‐risk human papillomavirus‐related cervical lesions: A hidden Markov model analysis of a single‐center cohort in Japan by Ikesu, Ryo, Taguchi, Ayumi, Hara, Konan, Kawana, Kei, Tsuruga, Tetsushi, Tomio, Jun, Osuga, Yutaka

“…Introduction Previous studies have shown that individuals with human papillomavirus (HPV)‐related cervical lesions have different prognoses according to the…”
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Development of a deep learning method for improving diagnostic accuracy for uterine sarcoma cases by Toyohara, Yusuke, Sone, Kenbun, Noda, Katsuhiko, Yoshida, Kaname, Kurokawa, Ryo, Tanishima, Tomoya, Kato, Shimpei, Inui, Shohei, Nakai, Yudai, Ishida, Masanori, Gonoi, Wataru, Tanimoto, Saki, Takahashi, Yu, Inoue, Futaba, Kukita, Asako, Kawata, Yoshiko, Taguchi, Ayumi, Furusawa, Akiko, Miyamoto, Yuichiro, Tsukazaki, Takehiro, Tanikawa, Michihiro, Iriyama, Takayuki, Mori-Uchino, Mayuyo, Tsuruga, Tetsushi, Oda, Katsutoshi, Yasugi, Toshiharu, Takechi, Kimihiro, Abe, Osamu, Osuga, Yutaka

“…Uterine sarcomas have very poor prognoses and are sometimes difficult to distinguish from uterine leiomyomas on preoperative examinations. Herein, we…”
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MED1, a novel binding partner of BRCA1, regulates homologous recombination and R-loop processing by Honjoh, Harunori, Tanikawa, Michihiro, Wada-Hiraike, Osamu, Oda, Katsutoshi, Inaba, Hirofumi, Kukita, Asako, Kawata, Yoshiko, Kusakabe, Misako, Tsuchimochi, Saki, Taguchi, Ayumi, Miyamoto, Yuichiro, Sone, Kenbun, Tsuruga, Tetsushi, Mori-Uchino, Mayuyo, Matsumoto, Yoko, Osuga, Yutaka

“…Homologous recombination (HR) is a major repair pathway of DNA double-strand breaks and is closely related to carcinogenesis. HR deficiency has been…”
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Mixed endometrioid and clear cell carcinoma arising from laparoscopic trocar site endometriosis by Tsuruga, Tetsushi, Hirata, Tetsuya, Akiyama, Ikumi, Matsumoto, Yoko, Oda, Katsutoshi, Fujii, Tomoyuki, Osuga, Yutaka

“…Laparoscopic port site endometriosis is less common in abdominal wall endometriosis, and malignant transformation of abdominal wall endometriosis is rare. We…”
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History of whole pelvis plus para-aortic radiation is a risk factor associated with febrile neutropenia during chemotherapy for recurrent cervical cancer by Nara, Katsuhiko, Taguchi, Ayumi, Tojima, Yuri, Miyamoto, Yuichiro, Tanikawa, Michihiro, Sone, Kenbun, Mori, Mayuyo, Tsuruga, Tetsushi, Yamamoto, Takehito, Takenaka, Ryosuke, Takada, Tappei, Osuga, Yutaka, Suzuki, Hiroshi

“…Background Radiation-based therapy is widely used for advanced cervical cancer. Prior radiation-based therapy is a potential risk factor for febrile…”
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Recurrent cervical cancer with PD‐L1 amplification treated with nivolumab: A case enrolled in the BELIEVE trial by Yoshimoto, Daisuke, Taguchi, Ayumi, Tanikawa, Michihiro, Sone, Kenbun, Shimoi, Tatsunori, Tsuruga, Tetsushi, Oda, Katsutoshi, Osuga, Yutaka

“…Patients with cervical cancer benefiting from immune checkpoint inhibitors (ICIs) are limited. Recently, PD‐L1 amplification has been attracted attention as a…”
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Manual vacuum aspiration (women's MVA) for endometrial biopsy for patients with suspected endometrial malignancies by Saito, Etsuko, Matsumoto, Yoko, Nitta, Satoshi, Fujino, Saho, Tsuruga, Tetsushi, Mori‐Uchino, Mayuyo, Iwase, Haruko, Kasamatsu, Takahiro, Kugu, Koji, Osuga, Yutaka

“…Aim Endometrial biopsy is generally performed with a metal uterine curette sonde; however, recently, many types of vacuum aspirators are available, including…”
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Anti-tumor activity of dual inhibition of phosphatidylinositol 3-kinase and MDM2 against clear cell ovarian carcinoma by Makii, Chinami, Ikeda, Yuji, Oda, Katsutoshi, Uehara, Yuriko, Nishijima, Akira, Koso, Takahiro, Kawata, Yoshiko, Kashiyama, Tomoko, Miyasaka, Aki, Sone, Kenbun, Tanikawa, Michihiro, Tsuruga, Tetsushi, Mori-Uchino, Mayuyo, Nagasaka, Kazunori, Matsumoto, Yoko, Wada-Hiraike, Osamu, Kawana, Kei, Hasegawa, Kosei, Fujiwara, Keiichi, Aburatani, Hiroyuki, Osuga, Yutaka, Fujii, Tomoyuki

“…AbstractIntroductionPI3K pathway signaling has received attention as a molecular target in clear cell ovarian carcinoma (CCOC). MDM2 is one of the AKT…”
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Endometrial cancer with concomitant endometriosis is highly associated with ovarian endometrioid carcinoma: a retrospective cohort study by Ishizaka, Aya, Taguchi, Ayumi, Tsuruga, Tetsushi, Maruyama, Marie, Kawata, Akira, Miyamoto, Yuichiro, Tanikawa, Michihiro, Ikemura, Masako, Sone, Kenbun, Mori, Mayuyo, Koga, Kaori, Ushiku, Tetsuo, Oda, Katsutoshi, Osuga, Yutaka

“…Abstract Background Endometriosis is assumed to be involved in ovarian cancer development, which is called endometriosis-associated ovarian cancer (EAOC)…”
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Genetic diagnosis of pseudomyxoma peritonei originating from mucinous borderline tumor inside an ovarian teratoma by Taguchi, Ayumi, Rokutan, Hirofumi, Oda, Katsutoshi, Tanikawa, Michihiro, Tanimoto, Saki, Sone, Kenbun, Mori, Mayuyo, Tsuruga, Tetsushi, Kohsaka, Shinji, Tatsuno, Kenji, Shinozaki-Ushiku, Aya, Miyagawa, Kiyoshi, Mano, Hiroyuki, Aburatani, Hiroyuki, Ushiku, Tetsuo, Osuga, Yutaka

“…Pseudomyxoma peritonei is a rare disease condition mainly caused by primary mucinous tumors from the appendix and rarely from the ovary, such as when mucinous…”
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