Search Results - "Tsung, Allan"

Surgery for Cancer: A Trigger for Metastases by Tohme, Samer, Simmons, Richard L, Tsung, Allan

“…Surgery is a crucial intervention and provides a chance of cure for patients with cancer. The perioperative period is characterized by an increased risk for…”
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Neutrophil Extracellular Traps Promote the Development and Progression of Liver Metastases after Surgical Stress by Tohme, Samer, Yazdani, Hamza O, Al-Khafaji, Ahmed B, Chidi, Alexis P, Loughran, Patricia, Mowen, Kerri, Wang, Yanming, Simmons, Richard L, Huang, Hai, Tsung, Allan

“…Risks of tumor recurrence after surgical resection have been known for decades, but the mechanisms underlying treatment failures remain poorly understood…”
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Damage‐associated molecular pattern–activated neutrophil extracellular trap exacerbates sterile inflammatory liver injury by Huang, Hai, Tohme, Samer, Al‐Khafaji, Ahmed B., Tai, Sheng, Loughran, Patricia, Chen, Li, Wang, Shu, Kim, Jiyun, Billiar, Timothy, Wang, Yanming, Tsung, Allan

“…Innate immunity plays a crucial role in the response to sterile inflammation such as liver ischemia/reperfusion (I/R) injury. The initiation of liver I/R…”
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Hypoxia induced HMGB1 and mitochondrial DNA interactions mediate tumor growth in hepatocellular carcinoma through Toll-like receptor 9 by Liu, Yao, Yan, Wei, Tohme, Samer, Chen, Man, Fu, Yu, Tian, Dean, Lotze, Michael, Tang, Daolin, Tsung, Allan

“…Background & Aims The mechanisms of hypoxia-induced tumor growth remain unclear. Hypoxia induces intracellular translocation and release of a variety of damage…”
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Biliary Tract Cancers: Treatment Updates and Future Directions in the Era of Precision Medicine and Immuno-Oncology by Manne, Ashish, Woods, Edward, Tsung, Allan, Mittra, Arjun

“…The effective management of biliary tract cancers (BTCs) has been hampered by limited options for systemic therapy. In recent years, the focus on precision…”
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Neutrophil extracellular traps promote inflammation and development of hepatocellular carcinoma in nonalcoholic steatohepatitis by van der Windt, Dirk J., Sud, Vikas, Zhang, Hongji, Varley, Patrick R., Goswami, Julie, Yazdani, Hamza O., Tohme, Samer, Loughran, Patricia, O'Doherty, Robert M., Minervini, Marta I., Huang, Hai, Simmons, Richard L., Tsung, Allan

“…Nonalcoholic steatohepatitis (NASH) is a progressive, inflammatory form of fatty liver disease. It is the most rapidly rising risk factor for the development…”
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Endogenous PAD4 in Breast Cancer Cells Mediates Cancer Extracellular Chromatin Network Formation and Promotes Lung Metastasis by Shi, Lai, Yao, Huanling, Liu, Zheng, Xu, Ming, Tsung, Allan, Wang, Yanming

“…Peptidyl arginine deiminase 4 (PAD4/PADI4) is a posttranslational modification enzyme that converts protein arginine or mono-methylarginine to citrulline. The…”
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Current Targets and Bioconjugation Strategies in Photodynamic Diagnosis and Therapy of Cancer by Gomez, Salvador, Tsung, Allan, Hu, Zhiwei

“…Photodynamic diagnosis (PDD) and therapy (PDT) are emerging, non/minimally invasive techniques for cancer diagnosis and treatment. Both techniques require a…”
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The Effects of Physical Exercise on Fatty Liver Disease by van der Windt, Dirk J., Sud, Vikas, Zhang, Hongji, Tsung, Allan, Huang, Hai

“…The increasing prevalence of obesity has made nonalcoholic fatty liver disease (NAFLD) the most common chronic liver disease. As a consequence, NAFLD and…”
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Robotic liver resection for malignancy: Current status, oncologic outcomes, comparison to laparoscopy, and future applications by Ocuin, Lee M., Tsung, Allan

“…Utilization of robotic techniques for resection of the liver is slowly gaining acceptance in specific situations and is now being applied to more challenging…”
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Molecular Biology of Liver Ischemia/Reperfusion Injury: Established Mechanisms and Recent Advancements by Klune, John R., MD, Tsung, Allan, MD

“…Hepatic ischemia/reperfusion (I/R) injury occurs in a variety of clinical contexts, including transplantation, liver resection surgery, trauma, and hypovolemic…”
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The impact of robotics in liver surgery: A worldwide systematic review and short‐term outcomes meta‐analysis on 2,728 cases by Ciria, Ruben, Berardi, Giammauro, Alconchel, Felipe, Briceño, Javier, Choi, Gi Hong, Wu, Yao‐Ming, Sugioka, Atsushi, Troisi, Roberto Ivan, Salloum, Chady, Soubrane, Olivier, Pratschke, Johann, Martinie, John, Tsung, Allan, Araujo, Raphael, Sucandy, Iswanto, Tang, Chung N., Wakabayashi, Go

“…Background The dissemination of robotic liver surgery is slow‐paced and must face the obstacle of demonstrating advantages over open and laparoscopic (LLS)…”
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Preoperative next-generation sequencing of pancreatic cyst fluid is highly accurate in cyst classification and detection of advanced neoplasia by Singhi, Aatur D, McGrath, Kevin, Brand, Randall E, Khalid, Asif, Zeh, Herbert J, Chennat, Jennifer S, Fasanella, Kenneth E, Papachristou, Georgios I, Slivka, Adam, Bartlett, David L, Dasyam, Anil K, Hogg, Melissa, Lee, Kenneth K, Marsh, James Wallis, Monaco, Sara E, Ohori, N Paul, Pingpank, James F, Tsung, Allan, Zureikat, Amer H, Wald, Abigail I, Nikiforova, Marina N

“…DNA-based testing of pancreatic cyst fluid (PCF) is a useful adjunct to the evaluation of pancreatic cysts (PCs). Mutations in / are highly specific for…”
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Neutrophil Extracellular Traps Drive Mitochondrial Homeostasis in Tumors to Augment Growth by Yazdani, Hamza O, Roy, Eva, Comerci, Alexander J, van der Windt, Dirk J, Zhang, Hongji, Huang, Hai, Loughran, Patricia, Shiva, Sruti, Geller, David A, Bartlett, David L, Tsung, Allan, Sheng, Tai, Simmons, Richard L, Tohme, Samer

“…Neutrophil infiltration and neutrophil extracellular traps (NET) in solid cancers are associated with poorer prognosis, but the mechanisms are incompletely…”
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iNOS promotes CD24⁺CD133⁺ liver cancer stem cell phenotype through a TACE/ADAM17-dependent Notch signaling pathway by Wang, Ronghua, Li, Yawen, Tsung, Allan, Huang, Hai, Du, Qiang, Yang, Muqing, Deng, Meihong, Xiong, Si, Wang, Xiju, Zhang, Liyong, Geller, David A., Cheng, Bin, Billiar, Timothy R.

“…The inducible nitric oxide synthase (iNOS) is associated with more aggressive solid tumors, including hepatocellular carcinoma (HCC). Notch signaling in cancer…”
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Neutrophil extracellular traps are indirectly triggered by lipopolysaccharide and contribute to acute lung injury by Liu, Shuai, Su, Xiaoli, Pan, Pinhua, Zhang, Lemeng, Hu, Yongbin, Tan, Hongyi, Wu, Dongdong, Liu, Ben, Li, Haitao, Li, Haosi, Li, Yi, Dai, Minhui, Li, Yuanyuan, Hu, Chengping, Tsung, Allan

“…Neutrophil extracellular traps (NETs) facilitate the extracellular killing of pathogens. However, excessive NETs formation and poor degradation are associated…”
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Time to Surgery and Colon Cancer Survival in the United States by Kaltenmeier, Christof, Shen, Chengli, Medich, David S., Geller, David A., Bartlett, David L., Tsung, Allan, Tohme, Samer

“…PURPOSE:Time to surgery (TTS) is of concern to patients diagnosed with cancer and their physicians. Controversy surrounds the impact of TTS on colon cancer…”
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Autophagy: Dual Response in the Development of Hepatocellular Carcinoma by Yazdani, Hamza O, Huang, Hai, Tsung, Allan

“…Autophagy is an evolutionary conserved intracellular mechanism which helps eukaryotic cells in maintaining their metabolic state to afford high-efficiency…”
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miR-375 Inhibits Autophagy and Reduces Viability of Hepatocellular Carcinoma Cells Under Hypoxic Conditions by Chang, Ying, Yan, Wei, He, Xingxing, Zhang, Lemeng, Li, Chuanjiang, Huang, Hai, Nace, Gary, Geller, David A, Lin, Jusheng, Tsung, Allan

“…Background & Aims Tumor cells survive hypoxic conditions by inducing autophagy. We investigated the roles of microRNAs (miRNAs) in regulating autophagy of…”
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Systematic review of the use of pre‐operative simulation and navigation for hepatectomy: current status and future perspectives by Hallet, Julie, Gayet, Brice, Tsung, Allan, Wakabayashi, Go, Pessaux, Patrick

“…Pre‐operative simulation using three‐dimensional (3D) reconstructions have been suggested to enhance surgical planning of hepatectomy. Evidence on its benefits…”
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