Search Results - "Tsunezumi, Jun"

Fibulin7 aggravates calcium oxalate‐induced acute kidney injury by binding to calcium oxalate crystals by Sugiura, Hidekazu, Tsunezumi, Jun, Yanagisawa, Hiromi, Futaya, Mayuko, Nitta, Kosaku, Tsuchiya, Ken

“…Fibulin7 (Fbln7) is a matricellular protein that is structurally similar to short fibulins but does not possess elastogenic abilities. Fbln7 is localized on…”
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Effects of M-1, a Major Metabolite of Sarpogrelate, on 5-HT-Induced Constriction of Isolated Human Internal Thoracic Artery by Tanaka-Totoribe, Naoko, Hidaka, Muneaki, Gamoh, Shuji, Yokota, Atsuko, Nakamura, Eisaku, Kuwabara, Masachika, Tsunezumi, Jun, Yamamoto, Ryuichi

“…Sarpogrelate, a selective 5-hydroxytryptamine (5-HT)2A receptor antagonist, inhibits 5-HT-induced platelet aggregation and vasoconstriction. It improves…”
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The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging by Raja, Erna, Changarathil, Gopakumar, Oinam, Lalhaba, Tsunezumi, Jun, Ngo, Yen Xuan, Ishii, Ryutaro, Sasaki, Takako, Imanaka‐Yoshida, Kyoko, Yanagisawa, Hiromi, Sada, Aiko

“…Tissue stem cells (SCs) divide infrequently as a protective mechanism against internal and external stresses associated with aging. Here, we demonstrate that…”
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Fibulin-7, a heparin binding matricellular protein, promotes renal tubular calcification in mice by Tsunezumi, Jun, Sugiura, Hidekazu, Oinam, Lalhaba, Ali, Aktar, Thang, Bui Quoc, Sada, Aiko, Yamashiro, Yoshito, Kuro-O, Makoto, Yanagisawa, Hiromi

“…Ectopic calcification occurs during development of chronic kidney disease and has a negative impact on long-term prognosis. The precise molecular mechanism and…”
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Dysregulation of fibulin-5 and matrix metalloproteases in epithelial ovarian cancer by Manders, Dustin B, Kishore, Hari Annavarapu, Gazdar, Adi F, Keller, Patrick W, Tsunezumi, Jun, Yanagisawa, Hiromi, Lea, Jayanthi, Word, Ruth Ann

“…Fibulin 5 (FBLN5) is an extracellular matrix glycoprotein that suppresses matrix metalloprotease 9 (MMP-9), angiogenesis and epithelial cell motility. Here, we…”
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Matrilysin (MMP-7) cleaves C-type lectin domain family 3 member A (CLEC3A) on tumor cell surface and modulates its cell adhesion activity by Tsunezumi, Jun, Higashi, Shouichi, Miyazaki, Kaoru

“…Matrilysin (MMP‐7) plays important roles in tumor progression. Previous studies have suggested that MMP‐7 binds to tumor cell surface and promotes their…”
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Matrilysin (matrix metalloprotease-7) cleaves membrane-bound annexin II and enhances binding of tissue-type plasminogen activator to cancer cell surfaces by Tsunezumi, Jun, Yamamoto, Kazuhiro, Higashi, Shouichi, Miyazaki, Kaoru

“…Matrilysin (matrix metalloproteinase-7) plays important roles in tumor progression. It was previously found that matrilysin binds to the surface of colon…”
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Binding of Active Matrilysin to Cell Surface Cholesterol Sulfate Is Essential for Its Membrane-associated Proteolytic Action and Induction of Homotypic Cell Adhesion by Yamamoto, Kazuhiro, Higashi, Shouichi, Kioi, Mitomu, Tsunezumi, Jun, Honke, Koichi, Miyazaki, Kaoru

“…Regulation of cell surface molecules by matrix metalloproteinases (MMPs), as well as MMPs-catalyzed degradation of extracellular matrix, is important for tumor…”
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Nephronectin Regulates Mesangial Cell Adhesion and Behavior in Glomeruli by Zimmerman, Susan E, Hiremath, Chitkale, Tsunezumi, Jun, Yang, Zhufeng, Finney, Bronwyn, Marciano, Denise K

“…A critical aspect of kidney function occurs at the glomerulus, the capillary network that filters the blood. The glomerular basement membrane (GBM) is a key…”
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Loss of fibulin-4 disrupts collagen synthesis and maturation: implications for pathology resulting from EFEMP2 mutations by Papke, Christina L, Tsunezumi, Jun, Ringuette, Léa-Jeanne, Nagaoka, Hideaki, Terajima, Masahiko, Yamashiro, Yoshito, Urquhart, Greg, Yamauchi, Mitsuo, Davis, Elaine C, Yanagisawa, Hiromi

“…Homozygous recessive mutations in either EFEMP2 (encoding fibulin-4) or FBLN5 (encoding fibulin-5), critical genes for elastogenesis, lead to autosomal…”
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Effects of M-1, a major metabolite of sarpogrelate, on 5-HT-induced constriction of isolated human internal thoracic artery by Tanaka-Totoribe, Naoko, Hidaka, Muneaki, Gamoh, Shuji, Yokota, Atsuko, Nakamura, Eisaku, Kuwabara, Masachika, Tsunezumi, Jun, Yamamoto, Ryuichi

“…Sarpogrelate, a selective 5-hydroxytryptamine (5-HT)2A receptor antagonist, inhibits 5-HT-induced platelet aggregation and vasoconstriction. It improves…”
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Role of CD34 family members in lumen formation in the developing kidney by Yang, Zhufeng, Zimmerman, Susan E., Tsunezumi, Jun, Braitsch, Caitlin, Trent, Cary, Bryant, David M., Cleaver, Ondine, González-Manchón, Consuelo, Marciano, Denise K.

“…Previous studies have shown CD34 family member Podocalyxin is required for epithelial lumen formation in vitro. We demonstrate that Endoglycan, a CD34 family…”
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Abstract 18657: Fibulin-4 Deficiency Alters Collagen Regulation in the Aortic Wall by Papke, Christina L, Ringuette, Lea-Jeanne, Yamashiro, Yoshito, Tsunezumi, Jun, Yamauchi, Mitsuo, Davis, Elaine, Yanagisawa, Hiromi

“…Abstract only Thoracic aortic aneurysms/dissections (TAAD) are a major cause of mortality each year in the U.S. Disruption of fibulin-4 (fbln4), an…”
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ABT-263, a Bcl-2 inhibitor, enhances the susceptibility of lung adenocarcinoma cells treated with Src inhibitors to anoikis by SAKUMA, Yuji, TSUNEZUMI, Jun, NAKAMURA, Yoshiyasu, YOSHIHARA, Mitsuyo, MATSUKUMA, Shoichi, KOIZUME, Shiro, MIYAGI, Yohei

“…The tyrosine kinase Src plays an important role in the development of anoikis resistance in lung adenocarcinomas. Several suspension lung adenocarcinoma cell…”
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