Search Results - "Tsumagari, Ryosuke"

Screening of subtype-specific activators and inhibitors for diacylglycerol kinase by Hayashi, Daiki, Tsumagari, Ryosuke, Liu, Ke, Ueda, Shuji, Yamanoue, Minoru, Sakane, Fumio, Shirai, Yasuhito

“…Abstract Diacylglycerol kinase (DGK) is a lipid kinase that converts diacylglycerol (DG) into phosphatidic acid (PA). DG and PA function as lipid messengers…”
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Precise Regulation of the Basal PKCγ Activity by DGKγ Is Crucial for Motor Coordination by Tsumagari, Ryosuke, Maruo, Kenta, Kakizawa, Sho, Ueda, Shuji, Yamanoue, Minoru, Saito, Hiromitsu, Suzuki, Noboru, Shirai, Yasuhito

“…Diacylglycerol kinase γ (DGKγ) is a lipid kinase to convert diacylglycerol (DG) to phosphatidic acid (PA) and indirectly regulates protein kinase C γ (PKCγ)…”
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Motor Dyscoordination and Alteration of Functional Correlation Between DGKγ and PKCγ in Senescence-Accelerated Mouse Prone 8 (SAMP8) by Tsumagari, Ryosuke, Maruo, Kenta, Nakao, Takaaki, Ueda, Shuji, Yamanoue, Minoru, Shirai, Yasuhito

“…Senescence-accelerated mouse prone 8 (SAMP8) is an animal model of age-related central nervous system (CNS) disorders. Although SAMP8 shows deficits in…”
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RalA, PLD and mTORC1 Are Required for Kinase-Independent Pathways in DGKβ-Induced Neurite Outgrowth by Kano, Takuya, Tsumagari, Ryosuke, Nakashima, Akio, Kikkawa, Ushio, Ueda, Shuji, Yamanoue, Minoru, Takei, Nobuyuki, Shirai, Yasuhito

“…Diacylglycerol kinase β (DGKβ) is an enzyme that converts diacylglycerol to phosphatidic acid and is mainly expressed in the cerebral cortex, hippocampus and…”
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Importance of diacylglycerol signaling in cerebellar motor coordination by Tsumagari, Ryosuke, Shirai, Yasuhito

“…Brain can be roughly divided into two parts, cerebrum and cerebellum. Cerebrum controls higher brain functions including memory, emotion and cognition, while…”
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mTORC1 is involved in DGKβ-induced neurite outgrowth and spinogenesis by Nakai, Hiroko, Tsumagari, Ryosuke, Maruo, Kenta, Nakashima, Akio, Kikkawa, Ushio, Ueda, Shuji, Yamanoue, Minoru, Saito, Naoaki, Takei, Nobuyuki, Shirai, Yasuhito

“…Diacylglycerol kinase β (DGKβ) is an enzyme converting DG to phosphatidic acid (PA) and is specifically expressed in neurons, especially those in the cerebral…”
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DGKγ Knock-Out Mice Show Impairments in Cerebellar Motor Coordination, LTD, and the Dendritic Development of Purkinje Cells through the Activation of PKCγ by Tsumagari, Ryosuke, Kakizawa, Sho, Kikunaga, Sakiko, Fujihara, Yoshitaka, Ueda, Shuji, Yamanoue, Minoru, Saito, Naoaki, Ikawa, Masahito, Shirai, Yasuhito

“…Diacylglycerol kinase γ (DGKγ) regulates protein kinase C (PKC) activity by converting DG to phosphatidic acid (PA). DGKγ directly interacts with PKCγ and is…”
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