Search Results - "Tsukiyama, Toshio"

H3K4 methylation at active genes mitigates transcription-replication conflicts during replication stress by Chong, Shin Yen, Cutler, Sam, Lin, Jing-Jer, Tsai, Cheng-Hung, Tsai, Huai-Kuang, Biggins, Sue, Tsukiyama, Toshio, Lo, Yi-Chen, Kao, Cheng-Fu

“…Transcription-replication conflicts (TRCs) occur when intensive transcriptional activity compromises replication fork stability, potentially leading to gene…”
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Dynamic changes in histone acetylation regulate origins of DNA replication by Unnikrishnan, Ashwin, Tsukiyama, Toshio, Gafken, Philip R

“…Histone modifications have been implicated in many DNA transactions. Using a mini-chromosome isolation and mass spectroscopy technique applicable to…”
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Nucleosome occupancy as a novel chromatin parameter for replication origin functions by Rodriguez, Jairo, Lee, Laura, Lynch, Bryony, Tsukiyama, Toshio

“…Eukaryotic DNA replication initiates from multiple discrete sites in the genome, termed origins of replication (origins). Prior to S phase, multiple origins…”
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ISWI and CHD chromatin remodelers bind promoters but act in gene bodies by Zentner, Gabriel E, Tsukiyama, Toshio, Henikoff, Steven

“…ATP-dependent nucleosome remodelers influence genetic processes by altering nucleosome occupancy, positioning, and composition. In vitro, Saccharomyces…”
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RSC primes the quiescent genome for hypertranscription upon cell-cycle re-entry by Cucinotta, Christine E, Dell, Rachel H, Braceros, Keean Ca, Tsukiyama, Toshio

“…Quiescence is a reversible G state essential for differentiation, regeneration, stem-cell renewal, and immune cell activation. Necessary for long-term…”
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Local chromatin fiber folding represses transcription and loop extrusion in quiescent cells by Swygert, Sarah G, Lin, Dejun, Portillo-Ledesma, Stephanie, Lin, Po-Yen, Hunt, Dakota R, Kao, Cheng-Fu, Schlick, Tamar, Noble, William S, Tsukiyama, Toshio

“…A longstanding hypothesis is that chromatin fiber folding mediated by interactions between nearby nucleosomes represses transcription. However, it has been…”
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Initiation of DNA replication from non-canonical sites on an origin-depleted chromosome by Bogenschutz, Naomi L, Rodriguez, Jairo, Tsukiyama, Toshio

“…Eukaryotic DNA replication initiates from multiple sites on each chromosome called replication origins (origins). In the budding yeast Saccharomyces…”
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ATR-like kinase Mec1 facilitates both chromatin accessibility at DNA replication forks and replication fork progression during replication stress by Rodriguez, Jairo, Tsukiyama, Toshio

“…Faithful DNA replication is essential for normal cell division and differentiation. In eukaryotic cells, DNA replication takes place on chromatin. This poses…”
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Chromatin Remodeling around Nucleosome-Free Regions Leads to Repression of Noncoding RNA Transcription by Yadon, Adam N., Van de Mark, Daniel, Basom, Ryan, Delrow, Jeffrey, Whitehouse, Iestyn, Tsukiyama, Toshio

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DNA Looping Facilitates Targeting of a Chromatin Remodeling Enzyme by Yadon, Adam N., Singh, Badri Nath, Hampsey, Michael, Tsukiyama, Toshio

“…ATP-dependent chromatin remodeling enzymes are highly abundant and play pivotal roles regulating DNA-dependent processes. The mechanisms by which they are…”
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ATP-Dependent Chromatin Remodeling Factors Tune S Phase Checkpoint Activity by Au, Tracey J., Rodriguez, Jairo, Vincent, Jack A., Tsukiyama, Toshio

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Purification and properties of an ATP-dependent nucleosome remodeling factor by Tsukiyama, Toshio, Wu, Carl

“…We report the purification of an ATP-dependent nucleosome remodeling factor (NURF) from Drosophila embryo extracts. NURF is composed of at least four…”
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The conserved HDAC Rpd3 drives transcriptional quiescence in S. cerevisiae by McKnight, Jeffrey N., Tsukiyama, Toshio

“…Quiescence is a ubiquitous cell cycle stage conserved from microbes through humans and is essential to normal cellular function and response to changing…”
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ISWI, a member of the SWl2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor by Tsukiyama, Toshio, Daniel, Carla, Tamkun, John, Wu, Carl

“…The generation of an accessible heat shock promoter in chromatin in vitro requires the concerted action of the GAGA transcription factor and NURF, an…”
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Activation of Saccharomyces cerevisiae HIS3 Results in Gcn4p-Dependent, SWI/SNF-Dependent Mobilization of Nucleosomes over the Entire Gene by Kim, Yeonjung, McLaughlin, Neil, Lindstrom, Kim, Tsukiyama, Toshio, Clark, David J.

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The ISWI Chromatin-Remodeling Protein Is Required for Gene Expression and the Maintenance of Higher Order Chromatin Structure In Vivo by Deuring, Renate, Fanti, Laura, Armstrong, Jennifer A, Sarte, Melinda, Papoulas, Ophelia, Prestel, Matthias, Daubresse, Gary, Verardo, Megan, Moseley, Sarah L, Berloco, Maria, Tsukiyama, Toshio, Wu, Carl, Pimpinelli, Sergio, Tamkun, John W

“…Drosophila ISWI, a highly conserved member of the SWI2/SNF2 family of ATPases, is the catalytic subunit of three chromatin-remodeling complexes: NURF, CHRAC,…”
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Interactions of Isw2 Chromatin Remodeling Complex with Nucleosomal Arrays: Analyses Using Recombinant Yeast Histones and Immobilized Templates by Gelbart, Marnie E., Rechsteiner, Thomas, Richmond, Timothy J., Tsukiyama, Toshio

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Widespread Collaboration of Isw2 and Sin3-Rpd3 Chromatin Remodeling Complexes in Transcriptional Repression by Fazzio, Thomas G., Kooperberg, Charles, Goldmark, Jesse P., Neal, Cassandra, Basom, Ryan, Delrow, Jeffrey, Tsukiyama, Toshio

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Isw1 Functions in Parallel with the NuA4 and Swr1 Complexes in Stress-Induced Gene Repression by Lindstrom, Kimberly C., Vary, Jay C., Parthun, Mark R., Delrow, Jeffrey, Tsukiyama, Toshio

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An efficient purification system for native minichromosome from Saccharomyces cerevisiae by Unnikrishnan, Ashwin, Akiyoshi, Bungo, Biggins, Sue, Tsukiyama, Toshio

“…We have recently established a system for purifying minichromosomes in a native state from Saccharomyces cerevisiae. This system is extremely efficient, and a…”
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