Search Results - "Tsukihara, Tomitake"

Crystallographic studies of cytochrome c and cytochrome c oxidase by Tsukihara, Tomitake

Get full text

Structure of the gap junction channel and its implications for its biological functions by Maeda, Shoji, Tsukihara, Tomitake

“…Gap junctions consist of arrays of intercellular channels composed of integral membrane proteins called connexin in vertebrates. Gap junction channels regulate…”
Get full text

Forty years of the structure of plant-type ferredoxin by Kurisu, Genji, Tsukihara, Tomitake

“…Abstract The X-ray structure of a [2Fe-2S]-type ferredoxin (Fd) from Spirulina platensis, solved by a collaborative group led by Profs Masao Kakudo, Yukiteru…”
Get full text

Structure of the connexin 26 gap junction channel at 3.5 Å resolution by Tsukihara, Tomitake, Maeda, Shoji, Nakagawa, So, Suga, Michihiro, Yamashita, Eiki, Oshima, Atsunori, Fujiyoshi, Yoshinori

“…Gap junctions consist of arrays of intercellular channels between adjacent cells that permit the exchange of ions and small molecules. Here we report the…”
Get full text

High-Resolution Structure of the Pre-microRNA Nuclear Export Machinery by Okada, Chimari, Yamashita, Eiki, Lee, Soo Jae, Shibata, Satoshi, Katahira, Jun, Nakagawa, Atsushi, Yoneda, Yoshihiro, Tsukihara, Tomitake

“…Nuclear export of microRNAs (miRNAs) by exportin-5 (Exp-5) is an essential step in miRNA biogenesis. Here, we present the 2.9 angstrom structure of the…”
Get full text

Complex structure of cytochrome c–cytochrome c oxidase reveals a novel protein–protein interaction mode by Shimada, Satoru, Shinzawa‐Itoh, Kyoko, Baba, Junpei, Aoe, Shimpei, Shimada, Atsuhiro, Yamashita, Eiki, Kang, Jiyoung, Tateno, Masaru, Yoshikawa, Shinya, Tsukihara, Tomitake

“…Mitochondrial cytochrome c oxidase (C c O) transfers electrons from cytochrome c (Cyt. c ) to O 2 to generate H 2 O, a process coupled to proton pumping. To…”
Get full text

Structure of human monoamine oxidase A at 2.2-Å resolution: The control of opening the entry for substrates/inhibitors by Son, Se-Young, Ma, Jichun, Kondou, Youhei, Yoshimura, Masato, Yamashita, Eiki, Tsukihara, Tomitake

“…The mitochondrial outer membrane-anchored monoamine oxidase (MAO) is a biochemically important flavoenzyme that catalyzes the deamination of biogenic and…”
Get full text

Critical roles of the CuB site in efficient proton pumping as revealed by crystal structures of mammalian cytochrome c oxidase catalytic intermediates by Shimada, Atsuhiro, Hara, Fumiyoshi, Shinzawa-Itoh, Kyoko, Kanehisa, Nobuko, Yamashita, Eiki, Muramoto, Kazumasa, Tsukihara, Tomitake, Yoshikawa, Shinya

“…Mammalian cytochrome c oxidase (CcO) reduces O2 to water in a bimetallic site including Fea3 and CuB giving intermediate molecules, termed A-, P-, F-, O-, E-,…”
Get full text

Determination of damage-free crystal structure of an X-ray–sensitive protein using an XFEL by Hirata, Kunio, Shinzawa-Itoh, Kyoko, Yano, Naomine, Takemura, Shuhei, Kato, Koji, Hatanaka, Miki, Muramoto, Kazumasa, Kawahara, Takako, Tsukihara, Tomitake, Yamashita, Eiki, Tono, Kensuke, Ueno, Go, Hikima, Takaaki, Murakami, Hironori, Inubushi, Yuichi, Yabashi, Makina, Ishikawa, Tetsuya, Yamamoto, Masaki, Ogura, Takashi, Sugimoto, Hiroshi, Shen, Jian-Ren, Yoshikawa, Shinya, Ago, Hideo

“…By combining the use of relatively large crystals and an X-ray free-electron laser, a radiation damage–free three-dimensional structure of a…”
Get full text

The Mg2+-containing Water Cluster of Mammalian Cytochrome c Oxidase Collects Four Pumping Proton Equivalents in Each Catalytic Cycle by Yano, Naomine, Muramoto, Kazumasa, Shimada, Atsuhiro, Takemura, Shuhei, Baba, Junpei, Fujisawa, Hidenori, Mochizuki, Masao, Shinzawa-Itoh, Kyoko, Yamashita, Eiki, Tsukihara, Tomitake, Yoshikawa, Shinya

“…Bovine heart cytochrome c oxidase (CcO) pumps four proton equivalents per catalytic cycle through the H-pathway, a proton-conducting pathway, which includes a…”
Get full text

Recent progress in experimental studies on the catalytic mechanism of cytochrome c oxidase by Shimada, Atsuhiro, Tsukihara, Tomitake, Yoshikawa, Shinya

“…Cytochrome oxidase (CcO) reduces molecular oxygen (O ) to water, coupled with a proton pump from the N-side to the P-side, by receiving four electrons…”
Get full text

Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection by Chen, Nai-Chi, Yoshimura, Masato, Guan, Hong-Hsiang, Wang, Ting-Yu, Misumi, Yuko, Lin, Chien-Chih, Chuankhayan, Phimonphan, Nakagawa, Atsushi, Chan, Sunney I, Tsukihara, Tomitake, Chen, Tzong-Yueh, Chen, Chun-Jung

“…Betanodaviruses cause massive mortality in marine fish species with viral nervous necrosis. The structure of a T = 3 Grouper nervous necrosis virus-like…”
Get full text

Charge at the 46th residue of connexin 50 is crucial for the gap‐junctional unitary conductance and transjunctional voltage‐dependent gating by Tong, Xiaoling, Aoyama, Hiroshi, Tsukihara, Tomitake, Bai, Donglin

“…Key points Gap‐junction (GJ) channels provide direct intercellular communication and are twice the length of most membrane channels, yet they often have high…”
Get full text

Bovine F1Fo ATP synthase monomers bend the lipid bilayer in 2D membrane crystals by Jiko, Chimari, Davies, Karen M, Shinzawa-Itoh, Kyoko, Tani, Kazutoshi, Maeda, Shintaro, Mills, Deryck J, Tsukihara, Tomitake, Fujiyoshi, Yoshinori, Kühlbrandt, Werner, Gerle, Christoph

“…We have used a combination of electron cryo-tomography, subtomogram averaging, and electron crystallographic image processing to analyse the structure of…”
Get full text

Higd1a is a positive regulator of cytochrome c oxidase by Hayashi, Takaharu, Asano, Yoshihiro, Shintani, Yasunori, Aoyama, Hiroshi, Kioka, Hidetaka, Tsukamoto, Osamu, Hikita, Masahide, Shinzawa-Itoh, Kyoko, Takafuji, Kazuaki, Higo, Shuichiro, Kato, Hisakazu, Yamazaki, Satoru, Matsuoka, Ken, Nakano, Atsushi, Asanuma, Hiroshi, Asakura, Masanori, Minamino, Tetsuo, Goto, Yu-ichi, Ogura, Takashi, Kitakaze, Masafumi, Komuro, Issei, Sakata, Yasushi, Tsukihara, Tomitake, Yoshikawa, Shinya, Takashima, Seiji

“…Cytochrome c oxidase (CcO) is the only enzyme that uses oxygen to produce a proton gradient for ATP production during mitochondrial oxidative phosphorylation…”
Get full text

Biological and immunological characteristics of hepatitis E virus-like particles based on the crystal structure by Yamashita, Tetsuo, Mori, Yoshio, Miyazaki, Naoyuki, Cheng, R. Holland, Yoshimura, Masato, Unno, Hideaki, Shima, Ryoichi, Moriishi, Kohji, Tsukihara, Tomitake, Li, Tian Cheng, Takeda, Naokazu, Miyamura, Tatsuo, Matsuura, Yoshiharu

“…Hepatitis E virus (HEV) is a causative agent of acute hepatitis. The crystal structure of HEV-like particles (HEV-LP) consisting of capsid protein was…”
Get full text

Bovine cytochrome c oxidase structures enable O₂ reduction with minimization of reactive oxygens and provide a proton-pumping gate by Muramoto, Kazumasa, Ohta, Kazuhiro, Shinzawa-Itoh, Kyoko, Kanda, Katsumasa, Taniguchi, Maki, Nabekura, Hiroyuki, Yamashita, Eiki, Tsukihara, Tomitake, Yoshikawa, Shinya

“…The O₂ reduction site of cytochrome c oxidase (CcO), comprising iron (Fea₃) and copper (CuB) ions, is probed by x-ray structural analyses of CO, NO, and CN⁻…”
Get full text

Structural and functional studies of gap junction channels by Nakagawa, So, Maeda, Shoji, Tsukihara, Tomitake

“…X-ray analysis of the human connexin26 gap junction channel has provided structural details of its open state. The gap junction channel is formed by paired…”
Get full text

Structures and physiological roles of 13 integral lipids of bovine heart cytochrome c oxidase by Shinzawa-Itoh, Kyoko, Aoyama, Hiroshi, Muramoto, Kazumasa, Terada, Hirohito, Kurauchi, Tsuyoshi, Tadehara, Yoshiki, Yamasaki, Akiko, Sugimura, Takashi, Kurono, Sadamu, Tsujimoto, Kazuo, Mizushima, Tsunehiro, Yamashita, Eiki, Tsukihara, Tomitake, Yoshikawa, Shinya

“…All 13 lipids, including two cardiolipins, one phosphatidylcholine, three phosphatidylethanolamines, four phosphatidylglycerols and three triglycerides, were…”
Get full text

Purification of Active Respiratory Supercomplex from Bovine Heart Mitochondria Enables Functional Studies by Shinzawa-Itoh, Kyoko, Shimomura, Harunobu, Yanagisawa, Sachiko, Shimada, Satoru, Takahashi, Ryoko, Oosaki, Marika, Ogura, Takashi, Tsukihara, Tomitake

“…To understand the roles of mitochondrial respiratory chain supercomplexes, methods for consistently separating and preparing supercomplexes must be…”
Get full text