Search Results - "Tsukada, Jun"
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1
The depiction of democracy in Japan's newspapers
Published in Asian journal of communication (02-01-2021)“…The goal of this article is to understand what 'kind' of democracy is being depicted by two Japanese major newspapers. The kind of democracy being disseminated…”
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The galanin signaling cascade is a candidate pathway regulating oncogenesis in human squamous cell carcinoma
Published in Genes chromosomes & cancer (01-02-2009)“…To identify putative biomarkers in squamous cell carcinoma (SCC), a survey of parallel chromosomal alterations and gene expression studies in 10 SCC cell lines…”
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Expression of the Suppressor of Cytokine Signaling-5 (SOCS5) Negatively Regulates IL-4-Dependent STAT6 Activation and Th2 Differentiation
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-2002)“…The development of helper T (Th) cell subsets, which secrete distinct cytokines, plays an important role in determining the type of immune response. The…”
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Identification of a novel therapeutic target for head and neck squamous cell carcinomas: A role for the neurotensin‐neurotensin receptor 1 oncogenic signaling pathway
Published in International journal of cancer (15-10-2008)“…Distant metastasis is a major factor associated with poor prognosis in head and neck squamous cell carcinomas (HNSCC), but little is known of its molecular…”
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Alternative Promoter Identified between a Hypermethylated Upstream Region of Repetitive Elements and a CpG Island in Human ABO Histo-blood Group Genes
Published in The Journal of biological chemistry (04-10-2002)“…We have studied the expression of human histo-blood group ABO genes during erythroid differentiation, using anex vivo culture of AC133−CD34+cells obtained from…”
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Transcriptional regulation of the human ABO histo-blood group genes is dependent on the N box upstream of the proximal promoter
Published in Transfusion (Philadelphia, Pa.) (01-12-2004)“…BACKGROUND: Our previous studies of the transcriptional regulation of the human ABO gene indicated that negative regulatory elements are present in the…”
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Langerhans Cell Histiocytosis of the Petrous Bone With Sudden Sensorineural Hearing Loss: Case Report
Published in Neurologia medico-chirurgica (2010)“…A 56-year-old woman with Langerhans cell histiocytosis of the petrous bone presented with sudden onset of sensorineural hearing loss and vertigo without other…”
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Computer simulation of the role of SOCS family protein in helper T cell differentiation
Published in International immunology (01-02-2006)“…The Th1/Th2 balance determines the nature of an immune response, and particular cytokines, IL-4 and IL-12, determine the direction at the initial stage of…”
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The role of suppressor of cytokine signaling 1 as a negative regulator for aberrant expansion of CD8α+ dendritic cell subset
Published in International immunology (01-09-2005)“…The suppressor of cytokine signaling (SOCS) 1 is a negative regulator in multiple cytokine-related aspects to maintain immunological homeostasis. Here, we…”
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Clinical and immunologic evaluation of dendritic cell-based immunotherapy in combination with gemcitabine and/or S-1 in patients with advanced pancreatic carcinoma
Published in Pancreas (01-03-2012)“…In the current study, we have evaluated the clinical and immunological responses in patients with advanced pancreatic carcinoma who received dendritic cell…”
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Regulation of αβ/γδ T Cell Lineage Commitment and Peripheral T Cell Responses by Notch/RBP-J Signaling
Published in Immunity (Cambridge, Mass.) (01-05-2004)Get full text
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The Interleukin-4 Enhancer CNS-2 Is Regulated by Notch Signals and Controls Initial Expression in NKT Cells and Memory-Type CD4 T Cells
Published in Immunity (Cambridge, Mass.) (01-06-2006)“…Epigenetic changes in chromatin structure at the T helper (Th2) locus correlate with interukin-4 (IL-4) and IL-13 expression during Th2 differentiation. By…”
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Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals
Published in Journal of oncology (04-11-2022)“…CD147 is an immunoglobulin-like receptor that is highly expressed in various cancers and involved in the growth, metastasis, and activation of inflammatory…”
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Abstract B095: Novel anti-CD147 antibodies inducing activation of SMAD signaling and tumor shrinkage in intractable cancer models
Published in Molecular cancer therapeutics (01-12-2019)“…Abstract CD147, a type I membrane protein, is highly expressed in various cancers and is involved in the growth, metastasis, and activation of inflammatory…”
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Abstract 4753: Anti-tumor effect of dendritic cell-based immunotherapy in combination with chemotherapy in the patients with advanced colorectal cancer
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Background and objective: Tumor-specific cytotoxic T lymphocytes (CTLs) can be activated in vivo by dendritic cell (DC)-based vaccination. However,…”
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Suppressor of Cytokine Signaling-1 Is Essential for Suppressing Dendritic Cell Activation and Systemic Autoimmunity
Published in Immunity (Cambridge, Mass.) (01-09-2003)“…Suppressor of cytokine signaling-1 (SOCS1/JAB) negatively regulates not only the cytokine-signaling pathway but also lipopolysaccharide (LPS)-induced…”
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The role of suppressor of cytokine signaling 1 as a negative regulator for aberrant expansion of CD8alpha+ dendritic cell subset
Published in International immunology (01-09-2005)“…The suppressor of cytokine signaling (SOCS) 1 is a negative regulator in multiple cytokine-related aspects to maintain immunological homeostasis. Here, we…”
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18
The role of suppressor of cytokine signaling 1 as a negative regulator for aberrant expansion of CD8 alpha super(+) dendritic cell subset
Published in International immunology (01-09-2005)“…The suppressor of cytokine signaling (SOCS) 1 is a negative regulator in multiple cytokine-related aspects to maintain immunological homeostasis. Here, we…”
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Regulation of [alpha][beta]/[gamma][delta] T Cell Lineage Commitment and Peripheral T Cell Responses by Notch/RBP-J Signaling
Published in Immunity (Cambridge, Mass.) (01-05-2004)“…RBP-J is a key mediator of Notch signaling that regulates a large spectrum of cell fate determinations. To elucidate the functions of Notch signaling in T cell…”
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20
Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling
Published in Immunity (Cambridge, Mass.) (01-05-2004)“…RBP-J is a key mediator of Notch signaling that regulates a large spectrum of cell fate determinations. To elucidate the functions of Notch signaling in T cell…”
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