Search Results - "Tsukada, Chiharu"

Functional Characterization of Wild-type and 49 CYP2D6 Allelic Variants for N-Desmethyltamoxifen 4-Hydroxylation Activity by Muroi, Yuka, Saito, Takahiro, Takahashi, Masamitsu, Sakuyama, Kanako, Niinuma, Yui, Ito, Miyabi, Tsukada, Chiharu, Ohta, Kiminori, Endo, Yasuyuki, Oda, Akifumi, Hirasawa, Noriyasu, Hiratsuka, Masahiro

“…Genetic variations in cytochrome P450 2D6 (CYP2D6) contribute to interindividual variability in the metabolism of clinically used drugs, e.g., tamoxifen…”
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Development and application of a rapid and sensitive genotyping method for pharmacogene variants using the single-stranded tag hybridization chromatographic printed-array strip (STH-PAS) by Kumondai, Masaki, Ito, Akio, Hishinuma, Eiji, Kikuchi, Aoi, Saito, Takahiro, Takahashi, Masamitsu, Tsukada, Chiharu, Saito, Sakae, Yasuda, Jun, Nagasaki, Masao, Minegishi, Naoko, Yamamoto, Masayuki, Kaneko, Akira, Teramoto, Isao, Kimura, Masatsugu, Hirasawa, Noriyasu, Hiratsuka, Masahiro

“…Genetic polymorphisms contribute to inter-individual variability in the metabolism of multiple clinical drugs, including warfarin, thiopurines, primaquine, and…”
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A method for atomic-level noncontact thermometry with electron energy distribution by Kinoshita, Ikuo, Tsukada, Chiharu, Ouchi, Kohei, Kobayashi, Eiichi, Ishii, Juntaro

“…We devised a new method of determining the temperatures of materials with their electron-energy distributions. The Fermi-Dirac distribution convoluted with a…”
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Functional characterization of 12 allelic variants of CYP2C8 by assessment of paclitaxel 6α-hydroxylation and amodiaquine N-deethylation by Tsukada, Chiharu, Saito, Takahiro, Maekawa, Masamitsu, Mano, Nariyasu, Oda, Akifumi, Hirasawa, Noriyasu, Hiratsuka, Masahiro

“…Cytochrome P450 2C8 (CYP2C8) is one of the enzymes primarily responsible for the metabolism of many drugs, including paclitaxel and amodiaquine. CYP2C8 genetic…”
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Functional characterization of 10 CYP4A11 allelic variants to evaluate the effect of genotype on arachidonic acid ω-hydroxylation by Saito, Takahiro, Honda, Masashi, Takahashi, Masamitsu, Tsukada, Chiharu, Ito, Miyabi, Katono, Yuki, Hosono, Hiroki, Saigusa, Daisuke, Suzuki, Naoto, Tomioka, Yoshihisa, Hirasawa, Noriyasu, Hiratsuka, Masahiro

“…Genetic variations in cytochrome P450 4A11 (CYP4A11) contributes to inter-individual variability in the metabolism of fatty acids such as arachidonic acid…”
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