Search Results - "Tsujishita, Y."

Specificity Determinants in Phosphoinositide Dephosphorylation: Crystal Structure of an Archetypal Inositol Polyphosphate 5-Phosphatase by Tsujishita, Yosuke, Guo, Shuling, Stolz, Leslie E., York, John D., Hurley, James H.

“…Inositol polyphosphate 5-phosphatases are central to intracellular processes ranging from membrane trafficking to Ca 2+ signaling, and defects in this activity…”
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Floundering about at cell membranes: a structural view of phospholipid signaling by H Hurley, James, Tsujishita, Yosuke, Pearson, MatthewA

“…Structures are now available for the majority of the enzyme families involved in the phosphorylation, dephosphorylation and hydrolysis of signaling…”
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Regulation of phospholipase A2 in human leukemia cell lines: its implication for intracellular signaling by Tsujishita, Y, Asaoka, Y, Nishizuka, Y

“…Permeabilized human leukemia HL-60 and U-937 cells suspended in an acidic or alkaline medium release various unsaturated fatty acids, most abundantly oleic and…”
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Structure and lipid transport mechanism of a StAR-related domain by Hurley, James H, Tsujishita, Yosuke

“…The steroidogenic acute regulatory protein (StAR) regulates acute steroidogenesis in the adrenal cortex and gonads by promoting the translocation of…”
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Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells by Shigemitsu, K, Tsujishita, Y, Hara, K, Nanahoshi, M, Avruch, J, Yonezawa, K

“…Amino acid deprivation of Chinese hamster ovary cells overexpressing human insulin receptors results in deactivation of p70 S6 kinase (p70) and…”
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Molecular Cloning and Characterization of a Novel p70 S6 Kinase, p70 S6 Kinase β Containing a Proline-rich Region by Gout, Ivan, Minami, Taichi, Hara, Kenta, Tsujishita, Yosuke, Filonenko, Valery, Waterfield, Michael D., Yonezawa, Kazuyoshi

“…A novel ribosomal S6 kinase, termed p70 S6 kinase β (p70β), which has a highly conserved amino acid sequence compared with that of p70/p85 S6 kinase (p70α)…”
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Structural genomics of lipid signaling domains by Tsujishita, Yosuke

“…Signaling domains have been identified by the analysis of data derived from biochemical studies, molecular cloning, or genetic studies. With the availability…”
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Comparative Mechanistic and Substrate Specificity Study of Inositol Polyphosphate 5-Phosphatase Schizosaccharomyces pombe Synaptojanin and SHIP2 by Chi, Yuling, Zhou, Bo, Wang, Wei-Qing, Chung, Sung-Kee, Kwon, Yong-Uk, Ahn, Young-Hoon, Chang, Young-Tae, Tsujishita, Yosuke, Hurley, James H, Zhang, Zhong-Yin

“…Inositol-5-phosphatases are important enzymes involved in the regulation of diverse cellular processes from synaptic vesicle recycling to insulin signaling. We…”
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Structural requirement of leucine for activation of p70 S6 kinase by Shigemitsu, Kaori, Tsujishita, Yosuke, Miyake, Hiroshi, Hidayat, Sujuti, Tanaka, Noriaki, Hara, Kenta, Yonezawa, Kazuyoshi

“…The addition of leucine induced activation of p70 S6k in amino acid-depleted H4IIE cells. Whereas the activation of p70 S6k by leucine was transient, the…”
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Alpha4 protein as a common regulator of type 2A-related serine/threonine protein phosphatases by Nanahoshi, Masakazu, Tsujishita, Yosuke, Tokunaga, Chiharu, Inui, Seiji, Sakaguchi, Nobuo, Hara, Kenta, Yonezawa, Kazuyoshi

“…The catalytic activity of the C subunit of serine/threonine phosphatase 2A is regulated by the association with A (PR65) and B subunits. It has been reported…”
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Regulation of Protein Phosphatase 2A Catalytic Activity by alpha4 Protein and Its Yeast Homolog Tap42 by Nanahoshi, Masakazu, Nishiuma, Teruaki, Tsujishita, Yosuke, Hara, Kenta, Inui, Seiji, Sakaguchi, Nobuo, Yonezawa, Kazuyoshi

“…Recent studies have revealed that the alpha4 protein, a mammalian homolog of yeast Tap42, is associated with the protein phosphatase 2A catalytic subunit…”
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Arachidonic Acid as a Messenger for the Expression of Long-Term Potentiation by Nishizaki, Tomoyuki, Nomura, Tamotsu, Matsuoka, Toshiyuki, Tsujishita, Yosuke

“…Arachidonic acid is suggested to play a role in the expression of long-term potentiation (LTP), a synaptic analog of memory and learning. However, it is…”
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Structural genomics and signaling domains by Hurley, James H, Anderson, D.Eric, Beach, Bridgette, Canagarajah, Bertram, Jonathan Ho, Yew Seng, Jones, Eudora, Miller, Greg, Misra, Saurav, Pearson, Matt, Saidi, Layla, Suer, Silke, Trievel, Ray, Tsujishita, Yosuke

“…Many novel signal transduction domains are being identified in the wake of genome sequencing projects and improved sensitivity in homology-detection…”
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Characterization of the Phosphoproteins and Protein Kinase Activity in mTOR Immunoprecipitates by Nishiuma, Teruaki, Hara, Kenta, Tsujishita, Yosuke, Kaneko, Kazue, Shii, Kozui, Yonezawa, Kazuyoshi

“…The mammalian target of rapamycin, mTOR, has been shown to be an upstream regulator of translational effectors. In the present study, in order to detect…”
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Regulation of phospholipase A(2) in human leukemia cell lines: Its implication for intracellular signaling by Tsujishita, Yosuke, Asaoka, Yoshinori, Nishizuka, Yasutomi

“…Permeabilized human leukemia HL-60 and U-937 cells suspended in an acidic or alkaline medium release various unsaturated fatty acids. Results of a study imply…”
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Ca2+‐independent cytosolic phospholipase A in HL‐60 cells differentiating to granulocytes by Hullin-Matsuda, Françoise, Tsujishita, Yosuke, Nishizuka, Yasutomi

“…The release of various fatty acids (FAs) from permeabilized HL‐60 cells, predominantly oleic acid (OA) rather than arachidonic acid, was greatly enhanced by…”
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Regulation of phospholipase A sub(2) in human leukemia cell lines: Its implication for intracellular signaling by Tsujishita, Y, Asaoka, Y, Nishizuka, Y

“…Permeabilized human leukemia HL-60 and U-937 cells suspended in an acidic or alkaline medium release various unsaturated fatty acids, most abundantly oleic and…”
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Characterization of Tyrosine-Phosphorylated   Isoform of Protein Kinase C Isolated from Chinese Hamster Ovary Cells by Kadotani, M., Nishiuma, T., Nanahoshi, M., Tsujishita, Y., Ogita, K., Nakamura, S.-i., Kikkawa, U., Asaoka, Y.

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Isolation and properties of a novel phospholipase A from rat brain that hydrolyses fatty acids at sn-1 and sn-2 positions by Yoshida, H, Tsujishita, Y, Hullin, F, Yoshida, K, Nakamura, S, Kikkawa, U, Asaoka, Y

“…A Ca(2+)-independent phospholipase A that releases various fatty acids from sn-1 and sn-2 positions was partially purified from rat brain soluble fraction. The…”
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Characterization of Tyrosine-Phosphorylated δ Isoform of Protein Kinase C Isolated from Chinese Hamster Ovary Cells by Kadotani, Makoto, Nishiuma, Teruaki, Nanahoshi, Masakazu, Tsujishita, Yosuke, Ogita, Kouji, Nakamura, Shun-ichi, Kikkawa, Ushio, Asaoka, Yoshinori

“…Phorbol ester treatment of Chinese hamster ovary cells stably overexpressing the δ isoform of protein kinase C induced the association of the isoform with the…”
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