Search Results - "Tsuji, Toshiyuki"

Decoding disease-causing mechanisms of missense mutations from supramolecular structures by Hijikata, Atsushi, Tsuji, Toshiyuki, Shionyu, Masafumi, Shirai, Tsuyoshi

“…The inheritance modes of pathogenic missense mutations are known to be highly associated with protein structures; recessive mutations are mainly observed in…”
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Vascular ADAM17 as a Novel Therapeutic Target in Mediating Cardiovascular Hypertrophy and Perivascular Fibrosis Induced by Angiotensin II by Takayanagi, Takehiko, Forrester, Steven J, Kawai, Tatsuo, Obama, Takashi, Tsuji, Toshiyuki, Elliott, Katherine J, Nuti, Elisa, Rossello, Armando, Kwok, Hang Fai, Scalia, Rosario, Rizzo, Victor, Eguchi, Satoru

“…Angiotensin II (AngII) has been strongly implicated in hypertension and its complications. Evidence suggests the mechanisms by which AngII elevates blood…”
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Role of Epidermal Growth Factor Receptor and Endoplasmic Reticulum Stress in Vascular Remodeling Induced by Angiotensin II by Takayanagi, Takehiko, Kawai, Tatsuo, Forrester, Steven J, Obama, Takashi, Tsuji, Toshiyuki, Fukuda, Yamato, Elliott, Katherine J, Tilley, Douglas G, Davisson, Robin L, Park, Joon-Young, Eguchi, Satoru

“…The mechanisms by which angiotensin II (AngII) elevates blood pressure and enhances end-organ damage seem to be distinct. However, the signal transduction…”
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Structure of the EndoMS-DNA Complex as Mismatch Restriction Endonuclease by Nakae, Setsu, Hijikata, Atsushi, Tsuji, Toshiyuki, Yonezawa, Kouki, Kouyama, Ken-ichi, Mayanagi, Kouta, Ishino, Sonoko, Ishino, Yoshizumi, Shirai, Tsuyoshi

“…Archaeal NucS nuclease was thought to degrade the single-stranded region of branched DNA, which contains flapped and splayed DNA. However, recent findings…”
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Epidermal growth factor receptor inhibitor protects against abdominal aortic aneurysm in a mouse model by Obama, Takashi, Tsuji, Toshiyuki, Kobayashi, Tomonori, Fukuda, Yamato, Takayanagi, Takehiko, Taro, Yoshinori, Kawai, Tatsuo, Forrester, Steven J, Elliott, Katherine J, Choi, Eric, Daugherty, Alan, Rizzo, Victor, Eguchi, Satoru

“…Angiotensin II (Ang II) has been implicated in the development of abdominal aortic aneurysm (AAA). In vascular smooth muscle cells (VSMC), Ang II activates…”
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Cortical microcirculatory disturbance in the super acute phase of subarachnoid hemorrhage - In vivo analysis using two-photon laser scanning microscopy by Ishikawa, Mami, Kajimura, Mayumi, Morikawa, Takayuki, Tsukada, Kosuke, Tsuji, Toshiyuki, Kusaka, Gen, Tanaka, Yuichi, Suematsu, Makoto

“…Abstract Objective Subarachnoid hemorrhage (SAH) causes cerebral ischemia and drastically worsens the clinical status at onset. However, the arterial flow is…”
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Caveolin 1 is critical for abdominal aortic aneurysm formation induced by angiotensin II and inhibition of lysyl oxidase by Takayanagi, Takehiko, Crawford, Kevin J, Kobayashi, Tomonori, Obama, Takashi, Tsuji, Toshiyuki, Elliott, Katherine J, Hashimoto, Tomoki, Rizzo, Victor, Eguchi, Satoru

“…Although AngII (angiotensin II) and its receptor AT1R (AngII type 1 receptor) have been implicated in AAA (abdominal aortic aneurysm) formation, the proximal…”
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Leukocyte plugging and cortical capillary flow after subarachnoid hemorrhage by Ishikawa, Mami, Kajimura, Mayumi, Morikawa, Takayuki, Tsukada, Kosuke, Tsuji, Toshiyuki, Kusaka, Gen, Tanaka, Yuichi, Suematsu, Makoto

“…Background It is believed that increased intracranial pressure immediately after subarachnoid hemorrhage (SAH) causes extensive brain ischemia and results in…”
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SOSUI-GramN: high performance prediction for sub-cellular localization of proteins in gram-negative bacteria by Imai, Kenichiro, Asakawa, Naoyuki, Tsuji, Toshiyuki, Akazawa, Fumitsugu, Ino, Ayano, Sonoyama, Masashi, Mitaku, Shigeki

“…A predictive software system, SOSUI-GramN, was developed for assessing the subcellular localization of proteins in Gram-negative bacteria. The system does not…”
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Theoretical study on the excited states of heteroarene chromophores: Comparison of calculated and experimental values by Tsuji, Toshiyuki, Onoda, Maki, Otani, Yuko, Ohwada, Tomohiko, Nakajima, Takahito, Hirao, Kimihiko

“…The SAC-CI method (S) with the CIS-optimized structure (C) is generally superior to other approaches to calculate emission energies of heteroaromatic…”
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Amplitude contrast of a single gadolinium atom reconstructed by a wave field restoration method by Takai, Yoshizo, Tsuji, Toshiyuki, Chikada, Hidekazu, Taya, Masaki

“…Single gadolinium atoms in fullerenes encapsulated in a single-wall carbon nanotube were observed by a wave field restoration method based on three-dimensional…”
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Deciphering Supramolecular Structures with Protein-Protein Interaction Network Modeling by Tsuji, Toshiyuki, Yoda, Takao, Shirai, Tsuyoshi

“…Many biological molecules are assembled into supramolecules that are essential to perform complicated functions in the cell. However, experimental information…”
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Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile–Induced Abdominal Aortic Aneurysm by Kawai, Tatsuo, Takayanagi, Takehiko, Forrester, Steven J, Preston, Kyle J, Obama, Takashi, Tsuji, Toshiyuki, Kobayashi, Tomonori, Boyer, Michael J, Cooper, Hannah A, Kwok, Hang Fai, Hashimoto, Tomoki, Scalia, Rosario, Rizzo, Victor, Eguchi, Satoru

“…Angiotensin II (AngII)–activated epidermal growth factor receptor has been implicated in abdominal aortic aneurysm (AAA) development. In vascular smooth muscle…”
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Abstract 099: EGF Receptor Inhibitor Erlotinib Prevented Abdominal Aortic Aneurysm But Not Hypertension Induced By Angiotensin II Plus Beta-aminopropionitrile by Tsuji, Toshiyuki, Obama, Takashi, Fukuda, Yamato, Elliott, Katherine, Eguchi, Satoru

“…Enhancement of the renin angiotensin II (AngII) system has been implicated in the development of abdominal aortic aneurysm (AAA). However, detailed molecular…”
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Palladium-catalyzed cross-coupling reactions of triarylbismuthanes with terminal alkynes under aerobic conditions by Matsumura, Mio, Yamada, Mizuki, Tsuji, Toshiyuki, Murata, Yuki, Kakusawa, Naoki, Yasuike, Shuji

“…A simple Pd-catalyzed Sonogashira-type cross-coupling reaction using of triarylbismuthanes is described. The reaction of triarylbismuthanes with terminal…”
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Clinical significance of the coexistence of carotid artery plaque and white matter disease in patients with symptomatic cerebral infarction by Ishikawa, Mami, Sugawara, Hitoshi, Tsuji, Toshiyuki, Nagai, Mutsumi, Kusaka, Gen, Naritaka, Heiji

“…•The unique features of carotid artery plaque and white matter disease (WMD) in cerebral infarction (CI) were investigated.•The increased means of measures…”
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Classification of ligand molecules in PDB with graph match-based structural superposition by Shionyu-Mitsuyama, Clara, Hijikata, Atsushi, Tsuji, Toshiyuki, Shirai, Tsuyoshi

“…The fast heuristic graph match algorithm for small molecules, COMPLIG, was improved by adding a structural superposition process to verify the atom–atom…”
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Exonuclease processivity of archaeal replicative DNA polymerase in association with PCNA is expedited by mismatches in DNA by Yoda, Takuya, Tanabe, Maiko, Tsuji, Toshiyuki, Yoda, Takao, Ishino, Sonoko, Shirai, Tsuyoshi, Ishino, Yoshizumi, Takeyama, Haruko, Nishida, Hirokazu

“…Family B DNA polymerases comprise polymerase and 3′ −>5′ exonuclease domains, and detect a mismatch in a newly synthesized strand to remove it in cooperation…”
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Amphiphilicity index of polar amino acids as an aid in the characterization of amino acid preference at membrane–water interfaces by Mitaku, Shigeki, Hirokawa, Takatsugu, Tsuji, Toshiyuki

“…Motivation: An amphiphilicity index of amino acid residues was developed for improving the method of transmembrane helix prediction. Results: The transfer…”
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Abstract 019: Vascular Smooth Muscle ADAM17 Contributes To Angiotensin II-induced Abdominal Aortic Aneurysm Formation But Not Hypertension In Mice by Tsuji, Toshiyuki, Takayanagi, Takehiko, Elliott, Katherine, Obama, Takashi, Crawford, Kevin, Rizzo, Victor, Eguchi, Satoru

“…Enhancement of the renin angiotensin II (AngII) system has been implicated in the development of abdominal aortic aneurysm (AAA). However, detailed molecular…”
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