Search Results - "Tsui, Hing Wo"
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Functional Up-regulation of HERG K+ Channels in Neoplastic Hematopoietic Cells
Published in The Journal of biological chemistry (24-05-2002)“…Kv1.3 channels regulate proliferation of normal lymphocytes, but the role of voltage-gated potassium channels in transformed hematopoietic cells is not known…”
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2
Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene
Published in Nature genetics (01-06-1993)“…Mice with the recessive motheaten (me) or the allelic viable motheaten (mev) mutations express a severe autoimmune and immunodeficiency syndrome. We have shown…”
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3
Symptomatic Acute Reactive Arthritis After An Outbreak of Salmonella
Published in Journal of rheumatology (01-08-2008)“…Objective In 2005, 592 individuals in Ontario developed acute gastroenteritis, predominantly after consuming bean sprouts contaminated with Salmonella…”
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The role of LCN2 and LCN2-MMP9 in spondylitis radiographic development: gender and HLA-B27 status differences
Published in Arthritis research & therapy (08-07-2022)“…Background Male HLA-B27-positive radiographic-axial spondyloarthritis (r-axSpA) patients are prone to have severe spinal radiographic progression, but the…”
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Serial Lipocalin 2 and Oncostatin M levels reflect inflammation status and treatment response in axial spondyloarthritis
Published in Arthritis research & therapy (14-05-2021)“…Informative serum biomarkers for monitoring inflammatory activity and treatment responses in axial spondyloarthritis (axSpA) are lacking. We assessed whether…”
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Lipocalin 2 links inflammation and ankylosis in the clinical overlap of inflammatory bowel disease (IBD) and ankylosing spondylitis (AS)
Published in Arthritis research & therapy (18-03-2020)“…Little is known about the mechanisms underlying the clinical overlap between gut inflammation and joint ankylosis, as exemplified by the concurrence of…”
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7
Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis
Published in Annals of the rheumatic diseases (01-04-2010)“…To assess whether there is excess transmission of alleles from the ERAP1 ERAP2 locus in families with ankylosing spondylitis (AS). 199 multiplex families with…”
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Serum Cytokine Receptors in Ankylosing Spondylitis: Relationship to Inflammatory Markers and Endoplasmic Reticulum Aminopeptidase Polymorphisms
Published in Journal of rheumatology (01-09-2010)“…Endoplasmic reticulum aminopeptidase (ERAP)1 is associated with ankylosing spondylitis (AS) and is known to be involved in the clipping of the cytokine…”
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9
Retinol (vitamin A) and retinol-binding protein levels are decreased in ankylosing spondylitis: clinical and genetic analysis
Published in Journal of rheumatology (01-12-2007)“…OBJECTIVE: Retinol (vitamin A) plays an important role in bone structure and function. Treatment with retinoids has been associated with bone abnormalities…”
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The CPPDD-Associated ANKH M48T Mutation Interrupts the Interaction of ANKH with the Sodium/Phosphate Cotransporter PiT-1
Published in Journal of rheumatology (01-06-2009)“…Objective. Numerous dominant human homolog of progressive ankylosis ( ANKH ) mutations have been identified in familial calcium pyrophosphate dihydrate crystal…”
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Aberrant Chondrocyte Hypertrophy and Activation of β-Catenin Signaling Precede Joint Ankylosis in ank/ank Mice
Published in Journal of rheumatology (01-03-2012)“…We assessed the role of Ank in the maintenance of postnatal articular cartilage using the ank/ank mouse (mice homozygous for progressive ankylosis). We…”
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12
Toll‐like receptor 2 variants are associated with acute reactive arthritis
Published in Arthritis and rheumatism (01-11-2008)“…Objective We previously reported a recent outbreak of salmonellosis in which some individuals developed complications of the enteric infection. The objective…”
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13
B and T cells are not required for the viable motheaten phenotype
Published in The Journal of experimental medicine (01-02-1996)“…Hematopoietic cell phosphatase (HCP), encoded by the hcph gene, (also called PTP1C, SHP, SH-PTP1, and PTPN6) is deficient in motheaten (me/me), and the allelic…”
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14
Serum levels of novel noggin and sclerostin-immune complexes are elevated in ankylosing spondylitis
Published in Annals of the rheumatic diseases (01-10-2014)“…Unravelling the basis of joint inflammation and ankylosis represents a major challenge in ankylosing spondylitis (AS) research. As noggin (NOG) and sclerostin…”
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Lipocalin 2 links inflammation and ankylosis in the clinical overlap of inflammatory bowel disease
Published in Arthritis research & therapy (18-03-2020)Get full text
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Molecular mechanisms underlying SHP‐1 gene expression
Published in European journal of biochemistry (01-06-2002)“…SHP‐1, a protein‐tyrosine phosphatase with two src‐homology 2 domains, is expressed predominantly in hematopoietic and epithelial cells and has been implicated…”
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Murine SHP-1 Splice Variants with Altered Src Homology 2 (SH2) Domains
Published in The Journal of biological chemistry (30-07-1999)“…SHP-1 is a protein-tyrosine phosphatase with two Src homology 2 (SH2) domains. These SH2 domains determine which proteins SHP-1 associates with, but they also…”
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The genetic basis of ankylosing spondylitis: new insights into disease pathogenesis
Published in Application of clinical genetics (01-01-2014)“…Ankylosing spondylitis (AS) is a complex disease involving multiple risk factors, both genetic and environmental. AS patients are predominantly young men, and…”
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Aberrant Chondrocyte Hypertrophy and Activation of ß-Catenin Signaling Precede Joint Ankylosis in ank/ank Mice
Published in Journal of rheumatology (01-03-2012)Get full text
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Expression of cytokines and receptors in normal, immortalized, and malignant ovarian epithelial cell lines
Published in Anticancer research (01-07-2003)“…Ovarian carcinoma originates from the epithelial cells on the surface of the ovary. This study evaluates cytokine production by these cells. Normal human ovary…”
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