Search Results - "Tsugita, Makoto"
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PPARβ/δ regulates the human SIRT1 gene transcription via Sp1
Published in Endocrine Journal (01-01-2010)“…NAD-dependent deacetylase SIRT1 is known to be activated by caloric restriction and is related to longevity. A natural polyphenolic compound resveratrol is…”
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Hormonal Regulation of Acetyl-CoA Carboxylase Isoenzyme Gene Transcription
Published in ENDOCRINE JOURNAL (2010)“…Both glucocorticoid and insulin are known to have an anabolic effect on lipogenesis. Acetyl-CoA, an intermediate product of glycolysis, is supplied for fatty…”
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3
Spondylodiscitis and Achilles tendonitis due to gout
Published in Modern rheumatology (01-11-2014)“…Abstract The patient, a 62-year-old man with a 3-year history of hyperuricemia, presented with severe neck pain, Achilles enthesopathy and polyarthralgia. He…”
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Is the metabolic syndrome an intracellular Cushing state? Effects of multiple humoral factors on the transcriptional activity of the hepatic glucocorticoid-activating enzyme (11β-hydroxysteroid dehydrogenase type 1) gene
Published in Molecular and cellular endocrinology (26-03-2008)“…Although glucocorticoid, as “gluco-” literally implies, plays an important role in maintaining the blood glucose level, excess of glucocorticoid…”
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5
Predominant role of 25OHD in the negative regulation of PTH expression: Clinical relevance for hypovitaminosis D
Published in Life sciences (1973) (26-03-2008)“…Although severe deficiency of bioactive vitamin D (1,25OH2D) causes rickets, mild insufficiency of the hormone, known as hypovitaminosis D, is responsible for…”
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Corticotropin-releasing hormone (CRH) transgenic mice display hyperphagia with increased Agouti-related protein mRNA in the hypothalamic arcuate nucleus
Published in Endocrine Journal (2011)“…Although glucocorticoid-induced hyperphagia is observed in the patients with glucocorticoid treatment or Cushing’s syndrome, its molecular mechanism is not…”
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Hormonal Regulation of Glycolytic Enzyme Gene and Pyruvate Dehydrogenase Kinase/Phosphatase Gene Transcription
Published in ENDOCRINE JOURNAL (2009)“…Both glucocorticoid and insulin are known to have an anabolic effect on lipogenesis. The glycolytic pathway is a part of the lipogenic pathway in the liver,…”
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Insulin Enhancement of Cytokine-Induced Coagulation/Inflammation-Related Gene Transcription in Hepatocytes
Published in ENDOCRINE JOURNAL (2008)“…Hyperinsulinemia is a known risk factor for cardiovascular events, but its molecular basis is not completely understood. In this study, we examined the effects…”
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9
Rathke's Cleft Cyst with Short-Term Size Changes in Response to Glucocorticoid Replacement
Published in Endocrine Journal (2008)“…An 81-year-old man was admitted to our hospital because of general fatigue. Hormonal examination showed that he had panhypopituitarism and central diabetes…”
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10
PPARbeta/delta regulates the human SIRT1 gene transcription via Sp1
Published in Endocrine journal (2010)“…NAD-dependent deacetylase SIRT1 is known to be activated by caloric restriction and is related to longevity. A natural polyphenolic compound resveratrol is…”
Get full text
Journal Article -
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Corticotropin-releasing hormone (CRH) transgenic mice display hyperphagia with increased Agouti-related protein mRNA in the hypothalamic arcuate nucleus
Published in ENDOCRINE JOURNAL (2011)“…Although glucocorticoid-induced hyperphagia is observed in the patients with glucocorticoid treatment or Cushing's syndrome, its molecular mechanism is not…”
Get full text
Journal Article -
13
Rathke's Cleft Cyst with Short-Term Size Changes in Response to Glucocorticoid Replacement
Published in ENDOCRINE JOURNAL (2008)“…Abstract. An 81-year-old man was admitted to our hospital because of general fatigue. Hormonal examination showed that he had panhypopituitarism and central…”
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14
Glucocorticoid Receptor-β and Receptor-γ Exert Dominant Negative Effect on Gene Repression But Not on Gene Induction
Published in Endocrinology (Philadelphia) (01-07-2010)“…Glucocorticoid has diverse biological effects through induction or repression of its target genes via glucocorticoid receptor (GR). In addition to the…”
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Liver X Receptor α Is Involved in the Transcriptional Regulation of the 6-Phosphofructo-2-Kinase/ Fructose-2,6-Bisphosphatase Gene
Published in Diabetes (New York, N.Y.) (01-05-2012)“…The activity of 6-phosphofructo-1-kinase is strictly controlled by fructose-2,6-bisphosphate, the level of which is regulated by another enzyme,…”
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Glucocorticoid receptor plays an indispensable role in mineralocorticoid receptor-dependent transcription in GR-deficient BE(2)C and T84 cells in vitro
Published in Molecular and cellular endocrinology (10-04-2009)“…The mineralocorticoid receptor (MR) plays an important functional role in the central nervous system; however, the molecular mechanism of MR-dependent gene…”
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Differential regulation of 11β-hydroxysteroid dehydrogenase type-1 and -2 gene transcription by proinflammatory cytokines in vascular smooth muscle cells
Published in Life sciences (1973) (12-09-2008)“…Glucocorticoid hormone is activated by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) mainly in glucocorticoid-target organs such as the liver and the…”
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Liver X receptor [alpha] is involved in the transcriptional regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene
Published in Diabetes (New York, N.Y.) (01-05-2012)“…The activity of 6-phosphofi-ucto-1-kinase is strictly controlled by fructose-2,6-bisphosphate, the level of which is regulated by another enzyme,…”
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Multisignal regulation of the rat NMDA1 receptor subunit gene — A pivotal role of glucocorticoid-dependent transcription
Published in Life sciences (1973) (06-06-2008)“…Although excess of glucocorticoid causes neuronal damage with cognitive disorders, the molecular mechanism for this remains unclear. In this study, we examined…”
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Clinical implication of 18F-fluorodeoxyglucose PET/CT in monitoring disease activity in spondyloarthritis
Published in Rheumatology (Oxford, England) (01-04-2010)Get full text
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