Search Results - "Tsuchiya, Seishi"

Cationic liposomes induce apoptosis through p38 MAP kinase–caspase-8–Bid pathway in macrophage-like RAW264.7 cells by Iwaoka, Sayaka, Nakamura, Tomoko, Takano, Shuhei, Tsuchiya, Seishi, Aramaki, Yukihiko

“…We have demonstrated that cationic liposomes composed of stearylamine (SA‐liposomes) induce apoptosis in a variety of cells, but the mechanism responsible for…”
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Physicochemical properties of liposomes affecting apoptosis induced by cationic liposomes in macrophages by TAKANO, Shuhei, ARAMAKI, Yukihiko, TSUCHIYA, Seishi

“…Cationic liposomes are expected to be useful as nonviral vectors for gene delivery. Cationic liposomes showed cytotoxicity, and we proposed that the…”
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Induction of apoptosis in macrophages by cationic liposomes by Aramaki, Yukihiko, Takano, Shuhei, Tsuchiya, Seishi

“…The effects of liposomes on apoptosis in macrophages were evaluated from DNA content and DNA fragmentation. Cationic liposomes composed of different kinds of…”
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Phosphatidylserine-Specific Receptor Contributes to TGF-β Production in Macrophages through a MAP Kinase, ERK by Otsuka, Masaki, Goto, Kentaro, Tsuchiya, Seishi, Aramaki, Yukihiko

“…We explored the involvement of the phosphatidylserine (PS)-receptor in the production of TGF-β by macrophages treated with PS-liposomes. The binding of…”
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Induction of cancer cell-specific apoptosis by folate-labeled cationic liposomes by Yoshida, Tomomi, Oide, Naoko, Sakamoto, Takatoshi, Yotsumoto, Satoshi, Negishi, Yoichi, Tsuchiya, Seishi, Aramaki, Yukihiko

“…We have previously reported that cationic liposomes themselves can induce apoptosis in macrophages and lymphocytes. In this paper, we attempted the cancer…”
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Comparison of Inhibitory Effects of Polyanions on Nitric Oxide Production by Macrophages Stimulated with LPS by Otsuka, Masaki, Tsuchiya, Seishi, Aramaki, Yukihiko

“…In this paper, we investigated the inhibitory mechanism of the production of nitric oxide (NO) by polyanions and liposomes composed of phosphatidylserine…”
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Cationic Liposomes Induce Macrophage Apoptosis through Mitochondrial Pathway by Aramaki, Yukihiko, Takano, Shuhei, Tsuchiya, Seishi

“…To clarify the mechanism of apoptosis of the macrophage-like cell line RAW264.7 induced by cationic liposomes, we focused on the mitochondria and investigated…”
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Changes in Immune Responses to Mite Antigen Sensitized through Barrier-Disrupted Skin with CpG-Oligodeoxynucleotide in Mice by Inoue, Joe, Yotsumoto, Satoshi, Sakamoto, Takatoshi, Tsuchiya, Seishi, Aramaki, Yukihiko

“…CpG-oligodeoxynucleotide (CpG-ODN) plays a critical role in immunity via the augmentation of Th1 and suppression of Th2 responses. We examined here the effect…”
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Superoxide production from nonenzymatically glycated protein by Sakurai, Tamiko, Tsuchiya, Seishi

“…Nonenzymatically glycated human serum albumin and glycated poly-lysine(Lys) in vitro brought about the reduction of nitroblue tetrazolium and ferricytochrome c…”
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Induction of apoptosis in WEHI 231 cells by cationic liposomes by ARAMAKI, Y, TAKANO, S, ARIMA, H, TSUCHIYA, S

“…Liposomes are of considerable interest as drug carriers and immunoadjuvants. However, few investigators have studied the changes exerted by liposomes in the…”
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Intradermal Delivery of Antisense Oligonucleotides by the Pulse Depolarization Iontophoretic System by Aramaki, Yukihiko, Arima, Hidetoshi, Takahashi, Mamiko, Miyazaki, Eriko, Sakamoto, Takatoshi, Tsuchiya, Seishi

“…The intradermal delivery of an antisense oligonucleotide was examined by iontophoresis. In this experiment, the antisense sequence of [32P]-labeled…”
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NADPH–Oxidase may Contribute to IL-12 Production in Macrophages Stimulated with CpG Phosphorothioate Oligodeoxynucleotides by Aramaki, Yukihiko, Yotsumoto, Satoshi, Watanabe, Hiroyuki, Tsuchiya, Seishi

“…CpG oligodeoxynucleotides (CpG-ODN) could be expectes to act as an adjuvant for humoral and cellular immunities. The aim of this study was to clarify the…”
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Efficient Gene Transfer to Hepatoblastoma Cells through Asialoglycoprotein Receptor and Expression under the Control of the Cyclin A Promoter by Aramaki, Yukihiko, Lee, Insugi, Arima, Hidetoshi, Sakamoto, Takatoshi, Magami, Yasushi, Yoshimoto, Takayuki, Moriyasu, Fuminori, Mizuguchi, Junichiro, Koyanagi, Yasuhisa, Nikaido, Toshio, Tsuchiya, Seishi

“…Specific gene delivery into hepatoma cells by liposomes and specific gene expression under the control of the cyclin A promoter were examined in HepG2 cells, a…”
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Comparison of Inhibitory Effects of Polyanions On Nitric Oxide Production by Macrophages Stimulated With LPS by Masaki OTSUKA, Seishi TSUCHIYA, Yukihiko ARAMAKI

“…In this paper, we investigated the inhibitory mechanism of the production of nitric oxide (NO) by polyanions and liposounes composed of phosphatidylserine…”
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Inhibitory Effects of Negatively Charged Liposomes on Nitric Oxide Production from Macrophages Stimulated by LPS by Aramaki, Yukihiko, Nitta, Fumie, Matsuno, Ryozou, Morimura, Yumiko, Tsuchiya, Seishi

“…The effects of liposomes on nitric oxide (NO) productions induced by lipopolysaccharide were investigated using thioglycollate-induced mouse peritoneal…”
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Scavenger Receptors May Regulate Nitric Oxide Production from Macrophages Stimulated by LPS by Matsuno, Ryozo, Aramaki, Yukihiko, Arima, Hidetoshi, Tsuchiya, Seishi

“…The effects of scavenger receptor (SR) ligands on nitric oxide (NO) production were investigated using mouse peritoneal macrophages stimulated by LPS…”
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Receptor-mediated transfer of pSV2CAT DNA to a human hepatoblastoma cell line HepG2 using asialofetuin-labeled cationic liposomes by Hara, T, Aramaki, Y, Takada, S, Koike, K, Tsuchiya, S

“…Asialofetuin-labeled liposomes (AF-lps) were developed as a vector for gene transfer to hepatocytes. Plasmid pSV2CAT DNA which encodes bacterial…”
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Changes in Immune Responses to Mite Antigen Sensitized through Barrier-Disrupted Skin With CpG-Oligodeoxynucleotide in Mice by Joe INOUE, Satoshi YOTSUMOTO, Takatoshi SAKAMOTO, Seishi TSUCHIYA, Yukihiko ARAMAKI

“…CpG-oligodeoxynucleotide (CpG-ODN) plays a critical role in immunity via the augmentation of Th1 and suppression of Th2 responses. We examined here the effect…”
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Efficient Gene Transfer to EGF Receptor Overexpressing Cancer Cells by Means of EGF-Labeled Cationic Liposomes by Kikuchi, Akira, Sugaya, Susumu, Ueda, Hiroyuki, Tanaka, Kenichi, Aramaki, Yukihiko, Hara, Toshifumi, Arima, Hidetoshi, Tsuchiya, Seishi, Fuwa, Toru

“…Epidermal growth factor (EGF)-labeled cationic liposomes (EGF-liposomes) were prepared for efficient gene transfer vector to EGF receptor expressing cells…”
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Recognition of charged liposomes by rat peritoneal and splenic macrophages: effects of fibronectin on the uptake of charged liposomes by Aramaki, Yukihiko, Akiyama, Katsuhiko, Hara, Toshifumi, Tsuchiya, Seishi

“…Different recognition systems for charged liposomes were found in rat peritoneal and splenic macrophages. In peritoneal macrophages, significant uptake was…”
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