Search Results - "Tsuchiya, Norihiko"

Molecular‐targeted therapy in advanced renal cell carcinoma based on pharmacokinetics, pharmacodynamics and pharmacogenetics: A proposed strategy by Tsuchiya, Norihiko

“…In advanced renal cell carcinoma, a transition of drug therapies from cytokines to molecular‐targeted drugs and immune‐oncology drugs provides more clinical…”
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Avelumab Maintenance Therapy for Advanced or Metastatic Urothelial Carcinoma by Powles, Thomas, Park, Se Hoon, Voog, Eric, Caserta, Claudia, Valderrama, Begoña P, Gurney, Howard, Kalofonos, Haralabos, Radulović, Siniša, Demey, Wim, Ullén, Anders, Loriot, Yohann, Sridhar, Srikala S, Tsuchiya, Norihiko, Kopyltsov, Evgeny, Sternberg, Cora N, Bellmunt, Joaquim, Aragon-Ching, Jeanny B, Petrylak, Daniel P, Laliberte, Robert, Wang, Jing, Huang, Bo, Davis, Craig, Fowst, Camilla, Costa, Nuno, Blake-Haskins, John A, di Pietro, Alessandra, Grivas, Petros

“…Patients with advanced or metastatic urothelial cancer who had had a response to platinum-based chemotherapy were randomly assigned to best supportive care…”
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Surgical and focal treatment for metastatic renal cell carcinoma: A literature review by Naito, Sei, Kato, Tomoyuki, Tsuchiya, Norihiko

“…Accompanied by the development of systemic therapy for metastatic renal cell carcinoma, the concept of focal treatment, including surgical treatment, has been…”
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Avelumab first-line maintenance plus best supportive care (BSC) vs BSC alone for advanced urothelial carcinoma: JAVELIN Bladder 100 Japanese subgroup analysis by Tomita, Yoshihiko, Yamamoto, Yoshiaki, Tsuchiya, Norihiko, Kanayama, Hiroomi, Eto, Masatoshi, Miyake, Hideaki, Powles, Thomas, Yoshida, Mizuki, Koide, Yuichiro, Umeyama, Yoshiko, di Pietro, Alessandra, Uemura, Hirotsugu

“…Background The phase 3 JAVELIN Bladder 100 trial showed significantly prolonged overall survival (OS) with avelumab as first-line (1L) maintenance therapy +…”
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Effect of general self-efficacy on promoting health-related quality of life during recovery from radical prostatectomy: a 1-year prospective study by Kawaguchi, Kansuke, Kawazoe, Hisashi, Sakurai, Toshihiko, Nishida, Hayato, Kanno, Hidenori, Naito, Sei, Kato, Tomoyuki, Konta, Tsuneo, Tsuchiya, Norihiko, Sato, Wakako

“…Background The decline of health-related quality-of-life (QOL) during the year after radical prostatectomy is severe. General self-efficacy (GSE) is an…”
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Fibroblast growth factor receptor type 4 as a potential therapeutic target in clear cell renal cell carcinoma by Narisawa, Takafumi, Naito, Sei, Ito, Hiromi, Ichiyanagi, Osamu, Sakurai, Toshihiko, Kato, Tomoyuki, Tsuchiya, Norihiko

“…Several clear cell renal cell carcinoma (ccRCC) cases harbour fibroblast growth factor receptor 4 (FGFR4) gene copy number (CN) gains. In this study, we…”
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Machine learning diagnosis by immunoglobulin N‐glycan signatures for precision diagnosis of urological diseases by Iwamura, Hiromichi, Mizuno, Kei, Akamatsu, Shusuke, Hatakeyama, Shingo, Tobisawa, Yuki, Narita, Shintaro, Narita, Takuma, Yamashita, Shinichi, Kawamura, Sadafumi, Sakurai, Toshihiko, Fujita, Naoki, Kodama, Hirotake, Noro, Daisuke, Kakizaki, Ikuko, Nakaji, Shigeyuki, Itoh, Ken, Tsuchiya, Norihiko, Ito, Akihiro, Habuchi, Tomonori, Ohyama, Chikara, Yoneyama, Tohru

“…Early diagnosis of urological diseases is often difficult due to the lack of specific biomarkers. More powerful and less invasive biomarkers that can be used…”
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Significance of upfront cytoreductive nephrectomy stratified by IMDC risk for metastatic renal cell carcinoma in targeted therapy era – a multi-institutional retrospective study by Kato, Renpei, Naito, Sei, Numakura, Kazuyuki, Hatakeyama, Shingo, Koguchi, Tomoyuki, Kojima, Takahiro, Kawasaki, Yoshihide, Kandori, Shuya, Kawamura, Sadafumi, Arai, Yoichi, Ito, Akihiro, Nishiyama, Hiroyuki, Kojima, Yoshiyuki, Ohyama, Chikara, Habuchi, Tomonori, Tsuchiya, Norihiko, Obara, Wataru

“…Background This retrospective multicenter study aimed to evaluate the survival benefit of upfront cytoreductive nephrectomy (CN) in metastatic renal cell…”
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Body composition changes following chemotherapy for testicular germ cell tumor: obesity is the long-term problem by Takai, Yuki, Naito, Sei, Kanno, Hidenori, Yamagishi, Atsushi, Yagi, Mayu, Sakurai, Toshihiko, Nishida, Hayato, Yamanobe, Takuya, Kato, Tomoyuki, Tsuchiya, Norihiko

“…Metabolic syndrome is a long-term complication of systemic chemotherapy for testicular germ cell tumor (TGCT). It is believed to be caused by secondary…”
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Clinical outcomes and prognostic factors in patients with newly diagnosed metastatic prostate cancer initially treated with androgen deprivation therapy: a retrospective multicenter study in Japan by Narita, Shintaro, Hatakeyama, Shingo, Takahashi, Masahiro, Sakurai, Toshihiko, Kawamura, Sadafumi, Hoshi, Senji, Ishida, Masanori, Kawaguchi, Toshiaki, Ishidoya, Shigeto, Shimoda, Jiro, Sato, Hiromi, Koizumi, Atsushi, Mitsuzuka, Koji, Tochigi, Tatsuo, Tsuchiya, Norihiko, Ohyama, Chikara, Arai, Yoichi, Nomura, Kyoko, Habuchi, Tomonori

“…Purpose Clinical outcomes of patients with newly diagnosed metastatic hormone-naïve prostate cancer (mHNPC) and initially treated with androgen deprivation…”
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Effect of Extracellular Signal-Regulated Protein Kinase 5 Inhibition in Clear Cell Renal Cell Carcinoma by Kanno, Hidenori, Naito, Sei, Obara, Yutaro, Ito, Hiromi, Ichiyanagi, Osamu, Narisawa, Takafumi, Kato, Tomoyuki, Nagaoka, Akira, Tsuchiya, Norihiko

“…(1) Background: Extracellular signal-regulating kinase 5 (ERK5) has been implicated in many cellular functions, including survival, proliferation, and…”
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Efficacy and safety of nivolumab for renal cell carcinoma in patients over 75 years old from multiple Japanese institutes by Numakura, Kazuyuki, Kobayashi, Mizuki, Hatakeyama, Shingo, Naito, Sei, Horikawa, Yohei, Tanaka, Toshikazu, Kamada, Sachiko, Muto, Yumina, Yamamoto, Ryohei, Koizumi, Atsushi, Nara, Taketoshi, Kanda, Sohei, Saito, Mitsuru, Narita, Shintaro, Inoue, Takamitsu, Shimoda, Naotake, Tsuchiya, Norihiko, Ohyama, Chikara, Habuchi, Tomonori

“…Purpose Despite nivolumab being increasingly used for treating metastatic renal cell carcinoma (mRCC), differing findings have been reported about its efficacy…”
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GPI-80 Augments NF-κB Activation in Tumor Cells by Takeda, Yuji, Kurota, Yuta, Kato, Tomoyuki, Ito, Hiromi, Araki, Akemi, Nara, Hidetoshi, Saitoh, Shinichi, Tanaka, Nobuyuki, Tsuchiya, Norihiko, Asao, Hironobu

“…Recent studies have discovered a relationship between glycosylphosphatidylinositol (GPI)-anchored protein 80 (GPI-80)/VNN2 (80 kDa GPI-anchored protein) and…”
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Incidence and location of positive surgical margin among open, laparoscopic and robot-assisted radical prostatectomy in prostate cancer patients: a single institutional analysis by Koizumi, Atsushi, Narita, Shintaro, Nara, Taketoshi, Takayama, Koichiro, Kanda, Sohei, Numakura, Kazuyuki, Tsuruta, Hiroshi, Maeno, Atsushi, Huang, Mingguo, Saito, Mitsuru, Inoue, Takamitsu, Tsuchiya, Norihiko, Satoh, Shigeru, Nanjo, Hiroshi, Habuchi, Tomonori

“…To evaluate the positive surgical margin rates and locations in radical prostatectomy among three surgical approaches, including open radical prostatectomy,…”
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Ureteroureterostomy With Near-Infrared Ray Catheter in a Kidney Transplant by Takai, Satoshi, Nishida, Hayato, Fukuhara, Hiroki, Kurokawa, Masayuki, Tsuchiya, Norihiko

“…Transplant ureteral stenosis (US) is a complication of kidney transplantation (KT) that sometimes adversely affects kidney function. Endoscopic treatment may…”
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Impact of germline HLA genotypes on clinical outcomes in patients with urothelial cancer treated with pembrolizumab by Takahashi, Shuhei, Narita, Shintaro, Fujiyama, Nobuhiro, Hatakeyama, Shingo, Kobayashi, Takashi, Kato, Renpei, Naito, Sei, Sakatani, Toru, Kashima, Soki, Koizumi, Atsushi, Yamamoto, Ryohei, Nara, Taketoshi, Kanda, Souhei, Numakura, Kazuyuki, Saito, Mitsuru, Obara, Wataru, Tsuchiya, Norihiko, Ohyama, Chikara, Ogawa, Osamu, Habuchi, Tomonori

“…Human leukocyte antigen class I (HLA‐I) genotypes are suggested to influence the cancer response to checkpoint blockade immunotherapy. This study assessed the…”
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The impact of obesity and adiponectin signaling in patients with renal cell carcinoma: A potential mechanism for the "obesity paradox" by Ito, Ryuichi, Narita, Shintaro, Huang, Mingguo, Nara, Taketoshi, Numakura, Kazuyuki, Takayama, Koichiro, Tsuruta, Hiroshi, Maeno, Atsushi, Saito, Mitsuru, Inoue, Takamitsu, Tsuchiya, Norihiko, Satoh, Shigeru, Habuchi, Tomonori

“…Although obesity increases the risk of renal cell carcinoma (RCC), obese patients with RCC experience longer survival than non-obese patients. However, the…”
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Genetic polymorphisms in prostate cancer by Tsuchiya, Norihiko

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Clinical Impact of Detecting Low-Frequency Variants in Cell-Free DNA on Treatment of Castration-Resistant Prostate Cancer by Mizuno, Kei, Sumiyoshi, Takayuki, Okegawa, Takatsugu, Terada, Naoki, Ishitoya, Satoshi, Miyazaki, Yu, Kojima, Takahiro, Katayama, Hiromichi, Fujimoto, Naohiro, Hatakeyama, Shingo, Shiota, Masaki, Yoshimura, Koji, Matsui, Yoshiyuki, Narita, Shintaro, Matsumoto, Hiroaki, Kurahashi, Ryoma, Kanno, Hidenori, Ito, Katsuhiro, Kimura, Hiroko, Kamiyama, Yuki, Sunada, Takuro, Goto, Takayuki, Kobayashi, Takashi, Yamada, Hitoshi, Tsuchiya, Norihiko, Kamba, Tomomi, Matsuyama, Hideyasu, Habuchi, Tomonori, Eto, Masatoshi, Ohyama, Chikara, Ito, Akihiro, Nishiyama, Hiroyuki, Okuno, Hiroshi, Kamoto, Toshiyuki, Fujimoto, Akihiro, Ogawa, Osamu, Akamatsu, Shusuke

“…Although cell-free DNA (cfDNA) testing is expected to drive cancer precision medicine, little is known about the significance of detecting low-frequency…”
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Humoral and cellular immune response and the safety of third SARS-CoV-2 mRNA vaccine with longer interval after the second vaccination in kidney transplant recipients by Takai, Satoshi, Nishida, Hayato, Ito, Hiromi, Fukuhara, Hiroki, Nawano, Takaaki, Narisawa, Takafumi, Kanno, Hidenori, Yagi, Mayu, Yamagishi, Atsushi, Sakurai, Toshihiko, Naito, Sei, Kato, Tomoyuki, Morikane, Keita, Tsuchiya, Norihiko

“…We evaluated the humoral and cellular immune responses and safety of the third severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine with a…”
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