Search Results - "Tsuboi, Masahiro"

Comparison of pulmonary segmentectomy and lobectomy: Safety results of a randomized trial by Suzuki, Kenji, Saji, Hisashi, Aokage, Keiju, Watanabe, Shun-ichi, Okada, Morihito, Mizusawa, Junki, Nakajima, Ryu, Tsuboi, Masahiro, Nakamura, Shinichiro, Nakamura, Kenichi, Mitsudomi, Tetsuya, Asamura, Hisao

“…No definitive comparisons of surgical morbidity between segmentectomy and lobectomy for non–small cell lung cancer have been reported. We conducted a…”
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Osimertinib in Resected EGFR-Mutated Non–Small-Cell Lung Cancer by Wu, Yi-Long, Tsuboi, Masahiro, He, Jie, John, Thomas, Grohe, Christian, Majem, Margarita, Goldman, Jonathan W, Laktionov, Konstantin, Kim, Sang-We, Kato, Terufumi, Vu, Huu-Vinh, Lu, Shun, Lee, Kye-Young, Akewanlop, Charuwan, Yu, Chong-Jen, de Marinis, Filippo, Bonanno, Laura, Domine, Manuel, Shepherd, Frances A, Zeng, Lingmin, Hodge, Rachel, Atasoy, Ajlan, Rukazenkov, Yuri, Herbst, Roy S

“…The incidence of recurrence after curative resection among patients with stage IB, II, or IIIA non–small-cell lung cancer is high and is only slightly lower…”
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A single-arm study of sublobar resection for ground-glass opacity dominant peripheral lung cancer by Suzuki, Kenji, Watanabe, Shun-ichi, Wakabayashi, Masashi, Saji, Hisashi, Aokage, Keiju, Moriya, Yasumitsu, Yoshino, Ichiro, Tsuboi, Masahiro, Nakamura, Shinichiro, Nakamura, Kenichi, Mitsudomi, Tetsuya, Asamura, Hisao

“…The optimal mode of surgery for ground-glass opacity dominant peripheral lung cancer defined with thoracic thin-section computed tomography remains unknown. We…”
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The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies by Kumagai, Shogo, Togashi, Yosuke, Kamada, Takahiro, Sugiyama, Eri, Nishinakamura, Hitomi, Takeuchi, Yoshiko, Vitaly, Kochin, Itahashi, Kota, Maeda, Yuka, Matsui, Shigeyuki, Shibahara, Takuma, Yamashita, Yasuho, Irie, Takuma, Tsuge, Ayaka, Fukuoka, Shota, Kawazoe, Akihito, Udagawa, Hibiki, Kirita, Keisuke, Aokage, Keiju, Ishii, Genichiro, Kuwata, Takeshi, Nakama, Kenta, Kawazu, Masahito, Ueno, Toshihide, Yamazaki, Naoya, Goto, Koichi, Tsuboi, Masahiro, Mano, Hiroyuki, Doi, Toshihiko, Shitara, Kohei, Nishikawa, Hiroyoshi

“…Immune checkpoint blockade has provided a paradigm shift in cancer therapy, but the success of this approach is very variable; therefore, biomarkers predictive…”
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Genomic Profiling of Large-Cell Neuroendocrine Carcinoma of the Lung by Miyoshi, Tomohiro, Umemura, Shigeki, Matsumura, Yuki, Mimaki, Sachiyo, Tada, Satoshi, Makinoshima, Hideki, Ishii, Genichiro, Udagawa, Hibiki, Matsumoto, Shingo, Yoh, Kiyotaka, Niho, Seiji, Ohmatsu, Hironobu, Aokage, Keiju, Hishida, Tomoyuki, Yoshida, Junji, Nagai, Kanji, Goto, Koichi, Tsuboi, Masahiro, Tsuchihara, Katsuya

“…Although large-cell neuroendocrine carcinoma (LCNEC) of the lung shares many clinical characteristics with small-cell lung cancer (SCLC), little is known about…”
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Radiographically determined noninvasive adenocarcinoma of the lung: Survival outcomes of Japan Clinical Oncology Group 0201 by Asamura, Hisao, MD, Hishida, Tomoyuki, MD, Suzuki, Kenji, MD, Koike, Teruaki, MD, Nakamura, Kenichi, MD, Kusumoto, Masahiko, MD, Nagai, Kanji, MD, Tada, Hirohito, MD, Mitsudomi, Tetsuya, MD, Tsuboi, Masahiro, MD, Shibata, Taro, MSc, Fukuda, Haruhiko, MD

“…Objective The study objective was to evaluate the long-term survival of patients with radiographically determined noninvasive lung adenocarcinomas. Methods A…”
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Ground-Glass Opacity Is a Strong Prognosticator for Pathologic Stage IA Lung Adenocarcinoma by Miyoshi, Tomohiro, Aokage, Keiju, Katsumata, Shinya, Tane, Kenta, Ishii, Genichiro, Tsuboi, Masahiro

“…A ground-glass opacity (GGO) component on chest computed tomography (CT) pathologically corresponds to lepidic adenocarcinoma. However, the precise…”
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Randomized Phase III Study of Pemetrexed Plus Cisplatin Versus Vinorelbine Plus Cisplatin for Completely Resected Stage II to IIIA Nonsquamous Non-Small-Cell Lung Cancer by Kenmotsu, Hirotsugu, Yamamoto, Nobuyuki, Yamanaka, Takeharu, Yoshiya, Katsuo, Takahashi, Toshiaki, Ueno, Tsuyoshi, Goto, Koichi, Daga, Haruko, Ikeda, Norihiko, Sugio, Kenji, Seto, Takashi, Toyooka, Shinichi, Date, Hiroshi, Mitsudomi, Tetsuya, Okamoto, Isamu, Yokoi, Kohei, Saka, Hideo, Okamoto, Hiroaki, Takiguchi, Yuichi, Tsuboi, Masahiro

“…To evaluate the efficacy of pemetrexed plus cisplatin versus vinorelbine plus cisplatin as postoperative adjuvant chemotherapy in patients with pathologic…”
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Cancer-associated fibroblasts and the tumor microenvironment in non-small cell lung cancer by Suzuki, Jun, Tsuboi, Masahiro, Ishii, Genichiro

“…Non-small cell lung cancer (NSCLC) has a markedly poor prognosis as it progresses, and the prognosis is still unsatisfactory even with modern treatments…”
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Limited resection for early-stage non-small cell lung cancer as function-preserving radical surgery: a review by Aokage, Keiju, Yoshida, Junji, Hishida, Tomoyuki, Tsuboi, Masahiro, Saji, Hisashi, Okada, Morihito, Suzuki, Kenji, Watanabe, Syunichi, Asamura, Hisao

“…Since 'radical lobectomy' was reported by Cahan in 1960, the standard surgical care for lung cancer has been lobectomy, in which units of the lobe are excised…”
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Postoperative Chemotherapy Use and Outcomes From ADAURA: Osimertinib as Adjuvant Therapy for Resected EGFR-Mutated NSCLC by Wu, Yi-Long, John, Thomas, Grohe, Christian, Majem, Margarita, Goldman, Jonathan W, Kim, Sang-We, Kato, Terufumi, Laktionov, Konstantin, Vu, Huu Vinh, Wang, Zhijie, Lu, Shun, Lee, Kye Young, Akewanlop, Charuwan, Yu, Chong-Jen, de Marinis, Filippo, Bonanno, Laura, Domine, Manuel, Shepherd, Frances A, Zeng, Lingmin, Atasoy, Ajlan, Herbst, Roy S, Tsuboi, Masahiro

“…Adjuvant chemotherapy is recommended in patients with resected stages II to IIIA (and select IB) NSCLC; however, recurrence rates are high. In the phase 3…”
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Multicentre prospective observational study for pulmonary vein stump thrombus after anatomical lung resections by Hattori, Aritoshi, Takamochi, Kazuya, Shiono, Satoshi, Tsuboi, Masahiro, Maniwa, Yoshimasa, Suzuki, Kazuhiro, Suzuki, Kenji

“…Abstract   OBJECTIVES Our goal was to evaluate the incidence and frequent sites of pulmonary vein stump thrombus (PVST) formation after pulmonary resection…”
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Collagen type I induces EGFR‐TKI resistance in EGFR‐mutated cancer cells by mTOR activation through Akt‐independent pathway by Yamazaki, Shota, Higuchi, Youichi, Ishibashi, Masayuki, Hashimoto, Hiroko, Yasunaga, Masahiro, Matsumura, Yasuhiro, Tsuchihara, Katsuya, Tsuboi, Masahiro, Goto, Koichi, Ochiai, Atsushi, Ishii, Genichiro

“…Primary resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR‐TKIs) is a serious problem in lung adenocarcinoma patients harboring…”
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The International Association for the Study of Lung Cancer Global Survey on Molecular Testing in Lung Cancer by Smeltzer, Matthew P, Wynes, Murry W, Lantuejoul, Sylvie, Soo, Ross, Ramalingam, Suresh S, Varella-Garcia, Marileila, Meadows Taylor, Meghan, Richeimer, Kristin, Wood, Kelsey, Howell, Kristen E, Dalurzo, Mercedes Lilana, Felip, Enriqueta, Hollenbeck, Gina, Kerr, Keith, Kim, Edward S, Mathias, Clarissa, Pacheco, Jose, Postmus, Pieter, Powell, Charles, Tsuboi, Masahiro, Wistuba, Ignacio I, Wakelee, Heather A, Belani, Chandra P, Scagliotti, Giorgio V, Hirsch, Fred R

“…Access to targeted therapies for lung cancer depends on the accurate identification of patients' biomarkers through molecular testing. The International…”
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A prospective radiological study of thin-section computed tomography to predict pathological noninvasiveness in peripheral clinical IA lung cancer (Japan Clinical Oncology Group 0201) by Suzuki, Kenji, Koike, Teruaki, Asakawa, Takashi, Kusumoto, Masahiko, Asamura, Hisao, Nagai, Kanji, Tada, Hirohito, Mitsudomi, Tetsuya, Tsuboi, Masahiro, Shibata, Taro, Fukuda, Haruhiko, Kato, Harubumi

“…Pathological noninvasiveness needs to be precisely predicted in preoperative radiological examinations of patients with early lung cancer for the application…”
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Refractory Hepatic Lymphorrhea: Percutaneous Transhepatic Lymphangiography and Embolization with n-Butyl-2-Cyanoacrylate Glue by Hasegawa, Tetsuya, Tsuboi, Masahiro, Fukushima, Keisuke, Yukawa, Tomoki

“…Hepatic lymphorrhea is a leakage from the liver’s lymphatic ducts into the abdominal cavity and an extremely rare complication associated with injury of the…”
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Relationship between podoplanin-expressing cancer-associated fibroblasts and the immune microenvironment of early lung squamous cell carcinoma by Suzuki, Jun, Aokage, Keiju, Neri, Shinya, Sakai, Takashi, Hashimoto, Hiroko, Su, Yinghan, Yamazaki, Shota, Nakamura, Hiroshi, Tane, Kenta, Miyoshi, Tomohiro, Sugano, Masato, Kojima, Motohiro, Fujii, Satoshi, Kuwata, Takeshi, Ochiai, Atsushi, Tsuboi, Masahiro, Ishii, Genichiro

“…•Podoplanin (PDPN)+ cancer associated fibroblasts (CAFs) promotes cancer progression in non-small cell lung cancer.•PDPN+ CAFs showed higher expression of…”
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ADAURA: Phase III, Double-blind, Randomized Study of Osimertinib Versus Placebo in EGFR Mutation-positive Early-stage NSCLC After Complete Surgical Resection by Wu, Yi-Long, Herbst, Roy S., Mann, Helen, Rukazenkov, Yuri, Marotti, Marcelo, Tsuboi, Masahiro

“…Currently, the role of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors as adjuvant therapy for early-stage non–small-cell lung cancer after…”
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Uptake of collagen type I via macropinocytosis cause mTOR activation and anti-cancer drug resistance by Yamazaki, Shota, Su, Yinghan, Maruyama, Ami, Makinoshima, Hideki, Suzuki, Jun, Tsuboi, Masahiro, Goto, Koichi, Ochiai, Atsushi, Ishii, Genichiro

“…Collagen type I (Col I) is one of the major extracellular matrix proteins in the cancer tissue. Previously, we have reported that Col I induces epidermal…”
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Analysis of Epidermal Growth Factor Receptor Gene Mutation in Patients with Non–Small Cell Lung Cancer and Acquired Resistance to Gefitinib by KOSAKA, Takayuki, YATABE, Yasushi, ENDOH, Hideki, YOSHIDA, Kimihide, HIDA, Toyoaki, TSUBOI, Masahiro, TADA, Hirohito, KUWANO, Hiroyuki, MITSUDOMI, Tetsuya

“…Purpose: Non–small cell lung cancers carrying activating mutations in the gene for the epidermal growth factor receptor (EGFR) are highly sensitive to…”
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