Search Results - "Tsruya, Rachel"
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Rhomboid cleaves Star to regulate the levels of secreted Spitz
Published in The EMBO journal (07-03-2007)“…Intracellular trafficking of the precursor of Spitz (Spi), the major Drosophila EGF receptor (EGFR) ligand, is facilitated by the chaperone Star, a type II…”
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Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz
Published in Genes & development (15-01-2002)“…Spitz (Spi) is a TGFalpha homolog that is a cardinal ligand for the Drosophila EGF receptor throughout development. Cleavage of the ubiquitously expressed…”
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Unidirectional Notch signaling depends on continuous cleavage of Delta
Published in Development (Cambridge) (01-01-2005)“…Unidirectional signaling from cells expressing Delta (Dl) to cells expressing Notch is a key feature of many developmental processes. We demonstrate that the…”
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TMF ARA160 is a BC-box-containing protein that mediates the degradation of Stat3
Published in Oncogene (25-11-2004)“…TMF/ARA160 is a Golgi resident protein whose cellular functions have not been conclusively revealed. Herein we show that TMF/ARA160 can direct the proteasomal…”
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