Search Results - "Tsourkas, A"

Hybridization kinetics and thermodynamics of molecular beacons by Tsourkas, Andrew, Behlke, Mark A., Rose, Scott D., Bao, Gang

“…Molecular beacons are increasingly being used in many applications involving nucleic acid detection and quantification. The stem–loop structure of molecular…”
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Exploring silver as a contrast agent for contrast-enhanced dual-energy X-ray breast imaging by Karunamuni, R, Tsourkas, A, Maidment, A D A

“…Through prior monoenergetic modelling, we have identified silver as a potential alternative to iodine in dual-energy (DE) X-ray breast imaging. The purpose of…”
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Structure–function relationships of shared‐stem and conventional molecular beacons by Tsourkas, Andrew, Behlke, Mark A., Bao, Gang

“…Molecular beacons are oligonucleotide probes capable of forming a stem–loop hairpin structure with a reporter dye at one end and a quencher at the other end…”
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Efficient cytosolic delivery of molecular beacon conjugates and flow cytometric analysis of target RNA by Chen, Antony K, Behlke, Mark A, Tsourkas, Andrew

“…Fluorescent microscopy experiments show that when 2'-O-methyl-modified molecular beacons (MBs) are introduced into NIH/3T3 cells, they elicit a nonspecific…”
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Hybridization of 2′‐O‐methyl and 2′‐deoxy molecular beacons to RNA and DNA targets by Tsourkas, Andrew, Behlke, Mark A., Bao, Gang

“…Molecular beacons are stem–loop hairpin oligonucleotide probes labeled with a fluorescent dye at one end and a fluorescence quencher at the other end; they can…”
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Next Generation Nanoparticles for Enhanced Radiation Therapy and Diagnostic Imaging of Brain Tumors by Sun, L, Joh, D, Al-Zaki, A, Tsourkas, A, Kao, G, Dorsey, J

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A Novel ‘Theranostic’ Approach? Polymer-coated Gold Nanoparticles Show Durable Systemic Circulation, Are Readily Imaged, and Radiosensitize Human Cancer Cells and Tumors by Joh, D, Kao, G.D, Al Zaki, A, Murty, S, Tsourkas, A, Dorsey, J.F

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Selective Targeting of Brain Tumors With Nanoparticle-induced Radiosensitization and Contrast Enhancement by Sun, L., Joh, D., Stangl, M., Al-Zaki, A., Murty, S., Alonso-Basanta, M., Kao, G., Dorsey, J., Tsourkas, A.

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Imaging individual microRNAs in single mammalian cells in situ by Lu, Jing, Tsourkas, Andrew

“…MicroRNAs (miRNAs) are potent negative regulators of gene expression that have been implicated in most major cellular processes. Despite rapid advances in our…”
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Size, charge and concentration dependent uptake of iron oxide particles by non-phagocytic cells by Thorek, Daniel L.J, Tsourkas, Andrew

“…Abstract A promising new direction for contrast-enhanced magnetic resonance (MR) imaging involves tracking the migration and biodistribution of…”
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Superparamagnetic iron oxide nanoparticle probes for molecular imaging by Thorek, Daniel L J, Chen, Antony K, Czupryna, Julie, Tsourkas, Andrew

“…The field of molecular imaging has recently seen rapid advances in the development of novel contrast agents and the implementation of insightful approaches to…”
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04:12 PM Abstract No. 226 Glypican-3 optical molecular imaging enables in vivo detection and monitoring of response to adoptive immunotherapy by Habibollahi, P., Hui, J., Mercadante, M., Tsourkas, A., Nadolski, G., Hunt, S., Gade, T.

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03:00 PM Abstract No. 218 Novel anti-glypican-3 T-cell redirecting bispecific antibody for targeted adoptive immunotherapy of hepatocellular carcinoma by Habibollahi, P., Hui, J., Mercadante, M., Tsourkas, A., Nadolski, G., Hunt, S., Gade, T.

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Dual FRET molecular beacons for mRNA detection in living cells by Santangelo, Philip J., Nix, Brent, Tsourkas, Andrew, Bao, Gang

“…The ability to visualize in real‐time the expression level and localization of specific endogenous RNAs in living cells can offer tremendous opportunities for…”
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Targeting cartilage epidermal growth factor receptor signaling pathway for osteoarthritis treatment by Gui, T., Wei, Y., Luo, L., Yu, F., Yan, L., Yao, L., Zhong, L., Yu, W., Han, B., Patel, J., Beier, F., Shao, Z., Han, L., Mauck, R., Tsourkas, A., Ahn, J., Cheng, Z., Qin, L.

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Detection of Vascular Adhesion Molecule-1 Expression Using a Novel Multimodal Nanoparticle by Kelly, Kimberly A, Allport, Jennifer R, Tsourkas, Andrew, Shinde-Patil, Vivek R, Josephson, Lee, Weissleder, Ralph

“…Endothelial vascular adhesion molecule-1 (VCAM-1) is a critical component of the leukocyte–endothelial adhesion cascade, and its strict temporal and spatial…”
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Development of a novel bispecific antibody for targeted immunotherapy of hepatocellular carcinoma by Hui, J, Habibollahi, P, Noji, M, Tsourkas, A, Nadolski, G, Hunt, S, Gade, T

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Abstract No. 129 - Development of a novel bispecific antibody for targeted immunotherapy of hepatocellular carcinoma by Hui, J, Habibollahi, P, Noji, M, Tsourkas, A, Nadolski, G, Hunt, S, Gade, T

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Shedding light on health and disease using molecular beacons by Tsourkas, Andrew, Bao, Gang

“…The detection and identification of pathogens is often painstaking due to the low abundance of diseased cells in clinical samples. The genomic sequences of the…”
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Magnetic Relaxation Switch Immunosensors Detect Enantiomeric Impurities by Tsourkas, Andrew, Hofstetter, Oliver, Hofstetter, Heike, Weissleder, Ralph, Josephson, Lee

“…Purity check: The self‐assembly of magnetic nanoparticle sensors in the presence of stereoselective antibodies causes a decrease in the T2 relaxation time of…”
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