Search Results - "Tsoukatos, D C"

Highly constrained cyclic (S,S) ‐CXaaC‐ peptides as inhibitors of fibrinogen binding to platelets by KOUKI, A., MITSIOS, J. V., SAKARELLOS‐DAITSIOTIS, M., SAKARELLOS, C., TSELEPIS, A. D., TSIKARIS, V., TSOUKATOS, D. C.

“…The Arg‐Gly‐Asp RGD motif of adhesive proteins is recognized by the activated platelet integrin αIIbβ3. Binding of fibrinogen (Fg) to activated αIIbβ3 causes…”
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Platelet-activating factor acetylhydrolase and transacetylase activities in human plasma low-density lipoprotein by Tsoukatos, D C, Liapikos, T A, Tselepis, A D, Chapman, M J, Ninio, E

“…In this study, we demonstrate the presence of a transacetylase activity in human plasma low-density lipoprotein (LDL) that transfers short-chain fatty acids…”
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Platelet-activating factor formation during oxidative modification of low-density lipoprotein when PAF-acetylhydrolase has been inactivated by Liapikos, T A, Antonopoulou, S, Karabina, S P, Tsoukatos, D C, Demopoulos, C A, Tselepis, A D

“…A PAF aggregating activity corresponding to 427 +/- 91, 668 +/- 111 and 1319 +/- 217 pg/mg protein was detected when LDL was preincubated at pH 3.5 or with 4…”
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Copper-Catalyzed Oxidation Mediates PAF Formation in Human LDL Subspecies: Protective Role of PAF: Acetylhydrolase in Dense LDL by Tsoukatos, Demokritos C, Arborati, Muriel, Liapikos, Theodoros, Clay, Keith L, Murphy, Robert C, Chapman, M. John, Ninio, Ewa

“…Free radical-mediated oxidation of cholesterol-rich LDL plays a key role in atherogenesis and involves the formation of oxidized phospholipids with…”
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Platelet aggregatory response to platelet activating factor (PAF), ex vivo, and PAF-acetylhydrolase activity in patients with unstable angina : effect of c7E3 Fab (abciximab) therapy by TSELEPIS, A. D, GOUDEVENOS, J. A, TAMBAKI, A. P, MICHALIS, L, STROUMBIS, C. S, TSOUKATOS, D. C, ELISAF, M, SIDERIS, D. A

“…Platelet activation and aggregation is a dominant feature in the pathophysiology of unstable angina. The final step of platelet aggregation is mediated through…”
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Platelet-associated and secreted PAF-acetylhydrolase activity in patients with stable angina: sequential changes of the enzyme activity after angioplasty by Goudevenos, J., Tselepis, A. D., Vini, M. P., Michalis, L., Tsoukatos, D. C., Elisaf, M., Ninio, E., Sideris, D. A.

“…Background Platelet‐activating factor (PAF), the lipid mediator of inflammation and potent platelet agonist, can be hydrolysed and inactivated by…”
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LDL subfractions in patients with myocardial infarction: effect of smoking and beta-blocker treatment by Theodoraki, T G, Tsoukatos, D C, Karabina, S A, Rallidis, L S, Papageorgakis, N H, Tselepsis, A D

“…The aim of the present case-control study was to estimate, by density gradient ultracentrifugation, LDL heterogeneity in myocardial infarction, and to evaluate…”
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Isolation, Chemical Characterization, and Subcellular Distribution of 1-O-Alkyl-2-Acetyl-sn-Glycerol in Tetrahymena pyriformis Cells by Tellis, Constantinos, Tsoukatos, Demokritos C., Lekka, Marilena E.

“…1-O-Hexadecyl-2-acetyl-sn-glycerol, the immediate precursor of platelet-activating factor (PAF) in itsde novo formation,was detected in the protozoon…”
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Study of the glycogenolytic action of platelet activating factor in Tetrahymena pyriformis by Tsangaris, G T, Demopoulos, C A, Tsoukatos, D C, Kapoulas, V M

“…1. A novel action of AGEPC on non-inflammatory cells was revealed, namely the ability to stimulate glycogenolysis in Tetrahymena pyriformis cells. 2. The…”
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Involvement of phospholipids in apolipoprotein B modification during low density lipoprotein oxidation by Karakatsani, Angeliki I., Liapikos, Theodoros A., Troganis, Anastasios N., Tsoukatos, Demokritos C.

“…An increased amount of phospholipids remained attached on delipidated apolipoprotein B originated from oxidized low density lipoprotein (LDL). 31P nuclear…”
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Ion transport and regulation of Tetrahymena pyriformis in isotonic and hypotonic media by TSOUKATOS, D. C, KAPOULAS, V. M

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Semisynthetic Preparation of 1-O-hexadecyl-2-acetyl-sn-glyceryl-3- phosphorylcholine (Platelet Activating Factor) by Lekka, Marilena E., Tsoukatos, Demokritos C., Tselepis, Alexandras D., Kapoulas, Vassilios M.

“…1-O-hexadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (platelet activating factor, PAF), (1.9 μmol) was prepared from the total lipid extract of the protozoan…”
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Molecular and mechanistic characterization of platelet-activating factor-like bioactivity produced upon LDL oxidation by Androulakis, Nicolaos, Durand, Herve, Ninio, Ewa, Tsoukatos, Demokritos C

“…Oxidation of LDL is thought to be involved in both initiating and sustaining atherogenesis through the formation of proinflammatory lipids and the covalent…”
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Platelet-associated and secreted PAF-acetylhydrolase activity in patients with stable angina : Sequential changes of the enzyme activity after angioplasty. Editorial commentary by PETERS, R. J. G, MOONS, A. H. M, GOUDEVENOS, J, TSELEPIS, A. D, VINI, M. P, MICHALIS, L, TSOUKATOS, D. C, ELISAF, M, NINIO, E, SIDERIS, D. A

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Non-enzymatic platelet-activating factor formation by acetylated proteins by Thanou, Paraskevi G., Tsoukatos, Demokritos C.

“…Substantial amounts of platelet-activating factor (PAF 1- O-alkyl-2-acyl-sn-glycero-3-phosphocholine), the potent phospholipid mediator of allergic and…”
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Studies on the subcellular distribution of 1-O-alkyl-2-acetyl-sn-glycero phosphocholine (PAF) and on the enzymic activities involved in its biosynthesis within the ciliate Tetrahymena pyriformis by Tsoukatos, D C, Tselepis, A D, Lekka, M E

“…The ciliated protozoan Tetrahymena pyriformis contains platelet-activating factor (PAF) as a physiological minor lipid. Its subcellular localization was found…”
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