Search Results - "Tsouderos, Yannis"
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Health economics in the field of osteoarthritis: An Expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Published in Seminars in arthritis and rheumatism (01-12-2013)“…Abstract Objectives There is an important need to evaluate therapeutic approaches for osteoarthritis (OA) in terms of cost-effectiveness as well as efficacy…”
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Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia
Published in Aging clinical and experimental research (01-02-2016)“…Purpose Sarcopenia is an age-related muscle condition which is frequently a precursor of frailty, mobility disability and premature death. It has a high…”
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In vitro effects of S12911-2 on osteoclast function and bone marrow macrophage differentiation
Published in European journal of pharmacology (16-08-2002)“…In order to determine whether 5-[bis(carboxymethyl) amino]-2-carboxy4-cyano-3-thiopheneacetic acid distrontium salt (S12911-2) inhibits bone resorption by…”
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Can We Identify Patients with High Risk of Osteoarthritis Progression Who Will Respond to Treatment? A Focus on Biomarkers and Frailty
Published in Drugs & aging (01-07-2015)“…Osteoarthritis (OA), a disease affecting different patient phenotypes, appears as an optimal candidate for personalized healthcare. The aim of the discussions…”
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Assessment of health claims in the field of bone: a view of the Group for the Respect of Ethics and Excellence in Science (GREES)
Published in Osteoporosis international (01-01-2012)“…Summary Health claims for food products in Europe are permitted if the nutrient has been shown to have a beneficial nutritional or physiological effect. This…”
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An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen‐deficient rats
Published in Journal of bone and mineral research (01-05-1993)“…Trabecular bone loss in estrogen deficiency is associated with enhanced bone resorption with a smaller increase in bone formation. We previously reported that…”
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Quality of Life in Sarcopenia and Frailty
Published in Calcified tissue international (01-08-2013)“…The reduced muscle mass and impaired muscle performance that define sarcopenia in older individuals are associated with increased risk of physical limitation…”
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S 12911‐2 Inhibits Osteoclastic Bone Resorption In Vitro
Published in Journal of bone and mineral research (01-06-2003)“…The potential anti‐osteoporotic activity of the strontium compound, S12911, was tested on osteoclast‐like cells and on cultured fetal mouse long bones. From 1…”
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Mediator: who's to blame?
Published in The Lancet (British edition) (11-06-2011)Get full text
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Mediator: who's to blame?
Published in The Lancet (British edition) (2011)Get full text
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Mediator: who's to blame?
Published in The Lancet (British edition) (11-06-2011)“…[...] the "estimation" that 500-2000 deaths can be attributed to benfl uorex owing to valvulopathy is pure extrapolation using un justifi ed, hard-line…”
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Re: “Effect of long-term treatment with strontium ranelate on bone strontium content” by Bärenholdt et al. (Bone, 2009)
Published in Bone (New York, N.Y.) (01-11-2009)Get full text
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Strontium distribution and interactions with bone mineral in monkey iliac bone after strontium salt (S 12911) administration
Published in Journal of bone and mineral research (01-09-1996)“…The analysis of the interaction of strontium (Sr) with bone mineral is of interest because a new agent containing Sr (S 12911) has shown positive effects on…”
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Recommendations for an update of 2003 European regulatory requirements for registration of drugs to be used in the treatment of RA
Published in Current medical research and opinion (01-02-2011)“…Abstract Since 2003, the European Medicines Agency (EMA) document, 'Points to consider on clinical investigation of medicinal products other than NSAIDs…”
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Efficacy and acceptability of intranasal 17 β-oestradiol for menopausal symptoms: randomised dose-response study
Published in The Lancet (British edition) (08-05-1999)“…The benefit of oestrogen therapy for menopause symptoms is well recognised. However, the means of delivery currently available have disadvantages, including…”
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Total joint replacement of hip or knee as an outcome measure for structure modifying trials in osteoarthritis
Published in Osteoarthritis and cartilage (2005)“…The Group for the Respect of Ethics and Excellence in Science (GREES) organized a working group to assess the value of time to joint surgery as a potential…”
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Health claims assessment in the field of joint and cartilage: a consensus viewpoint of the Group for the Respect of Ethics and Excellence in Science
Published in Current medical research and opinion (01-04-2012)“…Abstract Introduction:In 2006, the European Parliament and Council issued a regulation (No. 1924/2006) for the nutrition and health claims made on foods,…”
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An Uncoupling Agent Containing Strontium Prevents Bone Loss by Depressing Bone Resorption and Maintaining Bone Formation in Estrogen‐Deficient Rats
Published in Journal of bone and mineral research (01-06-2005)“…Trabecular bone loss in estrogen deficiency is associated with enhanced bone resorption with a smaller increase in bone formation. We previously reported that…”
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Effects of Intranasal 17β-Estradiol on Bone Turnover and Serum Insulin-Like Growth Factor I in Postmenopausal Women
Published in The journal of clinical endocrinology and metabolism (01-07-1999)“…Estrogen therapy, using either oral or transdermal routes, decreases bone turnover and prevents postmenopausal bone loss. It has been suggested that oral and…”
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Models for assessing the cost-effectiveness of the treatment and prevention of osteoporosis
Published in Osteoporosis international (01-11-2002)Get full text
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