Search Results - "Tsoi, Sandra T F"

Dorzagliatin, a Dual-Acting Glucokinase Activator, Increases Insulin Secretion and Glucose Sensitivity in Glucokinase Maturity-Onset Diabetes of the Young and Recent-Onset Type 2 Diabetes by Chow, Elaine, Wang, Ke, Lim, Cadmon K P, Tsoi, Sandra T F, Fan, Baoqi, Poon, Emily, Luk, Andrea O Y, Ma, Ronald C W, Ferrannini, Ele, Mari, Andrea, Chen, Li, Chan, Juliana C N

“…Glucokinase (GK, gene symbol GCK) maturity-onset diabetes of the young (MODY) is caused by heterozygous inactivating mutations in GK and impaired glucose…”
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Comparison of β-Cell Function and Insulin Sensitivity Between Normal-Weight and Obese Chinese With Young-Onset Type 2 Diabetes by Fan, Yingnan, Chow, Elaine, Lim, Cadmon K P, Hou, Yong, Tsoi, Sandra T F, Fan, Baoqi, Lau, Eric S H, Kong, Alice P S, Ma, Ronald C W, Wu, Hongjiang, Chan, Juliana C N, Luk, Andrea O Y

“…Normal-weight individuals with usual-onset type 2 diabetes have reduced β-cell function and greater insulin sensitivity compared with their obese counterparts…”
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Precision Medicine to Redefine Insulin Secretion and Monogenic Diabetes-Randomized Controlled Trial (PRISM-RCT) in Chinese patients with young-onset diabetes: design, methods and baseline characteristics by O, Chun Kwan, Fan, Ying Nan, Fan, Baoqi, Lim, Cadmon, Lau, Eric S H, Tsoi, Sandra T F, Wan, Raymond, Lai, Wai Yin, Poon, Emily WM, Ho, Jane, Ho, Cherry Cheuk Yee, Fung, Chloe, Lee, Eric KP, Wong, Samuel YS, Wang, Maggie, Ozaki, Risa, Cheung, Elaine, Ma, Ronald Ching Wan, Chow, Elaine, Kong, Alice Pik Shan, Luk, Andrea, Chan, Juliana C N

“…IntroductionWe designed and implemented a patient-centered, data-driven, holistic care model with evaluation of its impacts on clinical outcomes in patients…”
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Monogenic diabetes in a Chinese population with young‐onset diabetes: A 17‐year prospective follow‐up study in Hong Kong by Tsoi, Sandra T. F., Lim, Cadmon, Ma, Ronald C. W., Lau, Eric S. H., Fan, Baoqi, Chow, Elaine, Kong, Alice P. S., Chan, Juliana C. N., Luk, Andrea O. Y.

“…Aims Asians have a high prevalence of young‐onset diabetes, but the pattern of monogenic diabetes is unknown. We aimed to determine the prevalence of monogenic…”
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1477-P: Polygenic Risk Score (PRS) Derived from Common Variants of Monogenic Diabetes Genes (MDG) Predicts Young Onset Diabetes (YOD) and Cardiovascular(CV)-Kidney Complications by O, Chun Kwan, Fan, Baoqi, Tsoi, Sandra TF, Tam, Claudia H, Wan, Raymond, Lau, Eric SH, Shi, Mai, Lim, Cadmon KP, Chow, Elaine, Kong, Alice P, Ma, Ronald C, Luk, Andrea, Chan, Juliana C

“…Introduction & Objectives: Monogenic diabetes are caused by rare mutations in genes usually implicated in β-cell reserve/function. Whether their common…”
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1829-PUB: Precision Medicine to Redefine Insulin Secretion and Monogenic Diabetes Randomised Controlled Trial (PRISM-RCT) in Chinese Patients with Young-Onset Diabetes—Study Design and Baseline Profile by LUK, ANDREA, FAN, YINGNAN, FAN, BAOQI, LIM, CADMON K.P., LAU, ERIC S.H., POON, EMILY W.M., TSOI, SANDRA T.F., OZAKI, RISA, MA, RONALD C., CHOW, ELAINE, KONG, ALICE P., CHAN, JULIANA C.

“…Background: Young-onset diabetes (YOD) is heterogenous in aetiologies and clinical phenotypes. The PRISM study is a 3-year randomised controlled trial to…”
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