Search Results - "Tsogoeva, Svetlana B"

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    Structural hybridization as a facile approach to new drug candidates by Sampath Kumar, Halmuthur M., Herrmann, Lars, Tsogoeva, Svetlana B.

    Published in Bioorganic & medicinal chemistry letters (01-12-2020)
    “…[Display omitted] Structural hybridization of preclinically and clinically validated pharmacologically active molecules has emerged as a promising tool to…”
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    Journal Article
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    Chiral BINOL-derived phosphoric acids: privileged Brønsted acid organocatalysts for C-C bond formation reactions by Zamfir, Alexandru, Schenker, Sebastian, Freund, Matthias, Tsogoeva, Svetlana B

    Published in Organic & biomolecular chemistry (07-12-2010)
    “…BINOL-derived phosphoric acids have emerged during the last five years as powerful chiral Brønsted acid catalysts in many enantioselective processes. The most…”
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    Journal Article
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    Recent progress in the development of synthetic hybrids of natural or unnatural bioactive compounds for medicinal chemistry by Tsogoeva, Svetlana B

    Published in Mini reviews in medicinal chemistry (01-08-2010)
    “…The present mini-review highlights the recent developments on different classes of synthetic hybrids of natural and/or unnatural bioactive compounds, the…”
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    Journal Article
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    Hückel and Möbius Aromaticity in Charged Sigma Complexes by Mauksch, Michael, Tsogoeva, Svetlana B.

    Published in Chemistry : a European journal (04-06-2019)
    “…In sigma complexes, intermediates in nucleophilic and electrophilic aromatic substitution and other reactions, delocalization in the aromatic ring is formally…”
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    Anti‐SARS‐CoV‐2 Inhibitory Profile of New Quinoline Compounds in Cell Culture‐Based Infection Models by Herrmann, Lars, Hahn, Friedrich, Wangen, Christina, Marschall, Manfred, Tsogoeva, Svetlana B.

    Published in Chemistry : a European journal (19-01-2022)
    “…The presently ongoing pandemic of human SARS‐CoV‐2 infections (COVID‐19) presents an enormous challenge in surveillance, vaccine and antiviral drug…”
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    Developments in Chiral Binaphthyl-Derived Brønsted/Lewis Acids and Hydrogen-Bond-Donor Organocatalysis by Schenker, Sebastian, Zamfir, Alexandru, Freund, Matthias, Tsogoeva, Svetlana B.

    Published in European Journal of Organic Chemistry (01-04-2011)
    “…In recent years, binaphthyl compounds have found frequent applications in the design of various asymmetric organocatalysts, because binaphthyl structures are…”
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    Book Review Journal Article
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    Demonstration of "Möbius" Aromaticity in Planar Metallacycles by Mauksch, Michael, Tsogoeva, SvetlanaB.

    Published in Chemistry : a European journal (12-07-2010)
    “…Möbius aromaticity, predicted by Edgar Heilbronner in 1964, is a stabilizing effect exhibited by 4 n electron fully conjugated cyclic molecules (or transition…”
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    Generation of Highly Enantioenriched Crystalline Products in Reversible Asymmetric Reactions with Racemic or Achiral Catalysts by Tsogoeva, Svetlana B, Wei, Shengwei, Freund, Matthias, Mauksch, Michael

    Published in Angewandte Chemie (International ed.) (01-01-2009)
    “…Backwards is better: By combining forward and backward reaction steps of a reversible chemical process (see scheme) with the physical processes of…”
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    Journal Article
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    Photoracemization‐Based Viedma Ripening of a BINOL Derivative by Belletti, Giuseppe, Tortora, Carola, Mellema, Indradevi D., Tinnemans, Paul, Meekes, Hugo, Rutjes, Floris P. J. T., Tsogoeva, Svetlana B., Vlieg, Elias

    Published in Chemistry : a European journal (16-01-2020)
    “…Viedma ripening is a deracemization process that has been used to deracemize a range of chiral molecules. The method has two major requirements: the compound…”
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    Journal Article
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    Chemical hybridization of sulfasalazine and dihydroartemisinin promotes brain tumor cell death by Ackermann, Annemarie, Çapcı, Aysun, Buchfelder, Michael, Tsogoeva, Svetlana B., Savaskan, Nicolai

    Published in Scientific reports (21-10-2021)
    “…Gliomas are primary brain tumors with still poor prognosis for the patients despite a combination of cytoreduction via surgery followed by a…”
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    (Iso)Quinoline–Artemisinin Hybrids Prepared through Click Chemistry: Highly Potent Agents against Viruses by Çapcı, Aysun, Lorion, Mélanie M., Mai, Christina, Hahn, Friedrich, Hodek, Jan, Wangen, Christina, Weber, Jan, Marschall, Manfred, Ackermann, Lutz, Tsogoeva, Svetlana B.

    Published in Chemistry : a European journal (16-09-2020)
    “…Viral infections cause life‐threatening diseases in millions of people worldwide every year and there is an urgent need for new, effective antiviral drugs…”
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    Enantioselective Cycloaddition Reactions Catalyzed by BINOL-Derived Phosphoric Acids and N-Triflyl Phosphoramides: Recent Advances by Held, Felix E, Grau, Dominik, Tsogoeva, Svetlana B

    Published in Molecules (03-09-2015)
    “…Over the last several years there has been a huge increase in the development and applications of new efficient organocatalysts for enantioselective pericyclic…”
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    Journal Article Book Review
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    Chiral Thiourea-Based Bifunctional Organocatalysts in the Asymmetric Nitro-Michael Addition: A Joint Experimental-Theoretical Study by Yalalov, Denis A., Tsogoeva, SvetlanaB., Schmatz, Stefan

    Published in Advanced synthesis & catalysis (01-05-2006)
    “…A highly enantioselective (84–92% ee) organocatalytic Michael addition of acetone to aromatic nitroolefins has been described. The transition state geometries…”
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    Treatment of Multidrug-Resistant Leukemia Cells by Novel Artemisinin-, Egonol-, and Thymoquinone-Derived Hybrid Compounds by Gruber, Lisa, Abdelfatah, Sara, Fröhlich, Tony, Reiter, Christoph, Klein, Volker, Tsogoeva, Svetlana B, Efferth, Thomas

    Published in Molecules (Basel, Switzerland) (06-04-2018)
    “…Two major obstacles for successful cancer treatment are the toxicity of cytostatics and the development of drug resistance in cancer cells during chemotherapy…”
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    Synthesis and in vitro Study of Artemisinin/Synthetic Peroxide‐Based Hybrid Compounds against SARS‐CoV‐2 and Cancer by Herrmann, Lars, Yaremenko, Ivan A., Çapcı, Aysun, Struwe, Julia, Tailor, Dhanir, Dheeraj, Arpit, Hodek, Jan, Belyakova, Yulia Yu, Radulov, Peter S., Weber, Jan, Malhotra, Sanjay V., Terent'ev, Alexander O., Ackermann, Lutz, Tsogoeva, Svetlana B.

    Published in ChemMedChem (04-05-2022)
    “…The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) cause life‐threatening diseases in millions of people worldwide, in particular,…”
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    Journal Article