Search Results - "Tsikas, D."

Phenotyping and outcome on contemporary management in a German cohort of patients with peripartum cardiomyopathy by Haghikia, A, Podewski, E, Libhaber, E, Labidi, S, Fischer, D, Roentgen, P, Tsikas, D, Jordan, J, Lichtinghagen, R, von Kaisenberg, C. S, Struman, Ingrid, Bovy, Nicolas, Sliwa, K, Bauersachs, J, Hilfiker-Kleiner, Denise

“…Peripartum cardiomyopathy (PPCM) is a life-threatening heart disease developing towards the end of pregnancy or in the months following delivery in previously…”
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Asymmetric dimethylarginine, arginine and homoarginine at 11–13 weeks’ gestation and preeclampsia: a case–control study by Khalil, A A, Tsikas, D, Akolekar, R, Jordan, J, Nicolaides, K H

“…The aim of this study was to investigate whether the nitric oxide (NO) pathway is altered in pregnancies that develop preeclampsia (PE). This was a nested…”
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Recent methodological advances in the mass spectrometric analysis of free and protein-associated 3-nitrotyrosine in human plasma by Tsikas, Dimitrios, Caidahl, Kenneth

“…l-Tyrosine and l-tyrosine residues in proteins are attacked by various reactive-nitrogen species (RNS) including peroxynitrite to form 3-nitrotyrosine (NO…”
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Endopeptidase inhibition attenuates the contraction induced by big endothelin‐1 of isolated human penile erectile tissue by Shahin, P., Rahardjo, H. E., Bannowsky, A., Tsikas, D., Sohn, M., Kuczyk, M. A., Ückert, S.

“…Summary Peptides, such as C‐type natriuretic peptide (CNP), vasoactive intestinal polypeptide (VIP) and endothelin 1 (ET‐1), are involved in the control of…”
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Bone marrow molecular alterations after myocardial infarction : Impact on endothelial progenitor cells by THUM, Thomas, FRACCAROLLO, Daniela, GALUPPO, Paolo, TSIKAS, Dimitrios, FRANTZ, Stefan, ERTL, Georg, BAUERSACHS, Johann

“…Standard drugs post-myocardial infarction (MI) such as angiotensin converting enzyme (ACE) and 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase…”
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Allergen Challenge Increases Anandamide in Bronchoalveolar Fluid of Patients With Allergic Asthma by Zoerner, A A, Stichtenoth, D O, Engeli, S, Batkai, S, Winkler, C, Schaumann, F, Janke, J, Holz, O, Krug, N, Tsikas, D, Jordan, J, Hohlfeld, J M

“…Preclinical studies suggest that the endocannabinoid anandamide restrains allergic airway obstruction and inflammation. Therefore, we applied saline or…”
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Early Renal Ischemia‐Reperfusion Injury in Humans Is Dominated by IL‐6 Release from the Allograft by De Vries, D. K., Lindeman, J. H. N., Tsikas, D., De Heer, E., Roos, A., De Fijter, J. W., Baranski, A. G., Van Pelt, J., Schaapherder, A. F. M.

“…The pathophysiology of ischemia/reperfusion (I/R) injury is complex, and current knowledge of I/R injury in humans is incomplete. In the present study, human…”
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Redox‐generated isoprostanes are associated with residual platelet activity in aspirin‐treated patients with stable coronary heart disease by SCHWEDHELM, E., BIEREND, A., MAAS, R., TRINKS, R., KOM, G. D., TSIKAS, D., BÖGER, R. H.

“…Aim: Insufficient platelet inhibition by low‐dose aspirin is associated with poor prognosis in patients with coronary heart disease (CHD). We sought to…”
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Quantitative determination of circulating and urinary asymmetric dimethylarginine (ADMA) in humans by gas chromatography–tandem mass spectrometry as methyl ester tri( N-pentafluoropropionyl) derivative by Tsikas, Dimitrios, Schubert, Bibiana, Gutzki, Frank-Mathias, Sandmann, Jörg, Frölich, Jürgen C

“…Asymmetric dimethylarginine (ADMA; N G, N G-dimethyl- l-arginine) is the most important endogenous inhibitor of nitric oxide synthase and a potential risk…”
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Incorrect and inconsistent use of homocysteine's nomenclature: a potential source of misunderstandings by Tsikas, D.

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Influence of dietary fat ingestion on asymmetrical dimethylarginine in lean and obese human subjects by Engeli, S, Tsikas, D, Lehmann, A.C, Böhnke, J, Haas, V, Strauß, A, Janke, J, Gorzelniak, K, Luft, F.C, Jordan, J

“…Abstract Background and Aims Asymmetrical dimethylarginine (ADMA) may contribute to hypertension and cardiovascular disease by decreasing NO formation. In…”
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Nebivolol decreases systemic oxidative stress in healthy volunteers by Troost, R., Schwedhelm, E., Rojczyk, S., Tsikas, D., Frölich, J. C.

“…Aims Nebivolol is a selective, vasodilatory β1‐adrenergic receptor antagonist which has been suggested to possess additional antioxidative properties. The aim…”
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Effects of normalization of plasma testosterone levels in hypogonadal men on plasma levels and urinary excretion of asymmetric dimethylarginine (ADMA) by Leifke, E, Kinzel, M, Tsikas, D, Gooren, L, Frölich, J C, Brabant, G

“…Elevated plasma levels of asymmetric dimethylarginine (ADMA) inhibit nitric oxide formation and exert a proatherogenic action. Low testosterone (T) levels are…”
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Methods of quantitative analysis of the nitric oxide metabolites nitrite and nitrate in human biological fluids by Tsikas, Dimitrios

“…In human organism, the gaseous radical molecule nitric oxide (NO) is produced in various cells from L-arginine by the catalytic action of NO synthases (NOS)…”
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Summary of a recent workshop/conference report on validation and implementation of bioanalytical methods: Implications on manuscript review in the Journal of Chromatography B by Bischoff, R., Hopfgartner, G., Karnes, H.T., Lloyd, D.K., Phillips, T.M., Tsikas, D., Xu, G.

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L-arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects by Bode-Böger, S M, Böger, R H, Creutzig, A, Tsikas, D, Gutzki, F M, Alexander, K, Frölich, J C

“…1. L-Arginine is the physiological precursor of nitric oxide which induces vasodilatation and inhibits platelet aggregation by the formation of cyclic GMP. 2…”
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Nitric oxide inhibits the secretion of T-helper 1- and T-helper 2-associated cytokines in activated human T cells by Bauer, H, Jung, T, Tsikas, D, Stichtenoth, D O, Frölich, J C, Neumann, C

“…Mechanisms regulating the balance of T-helper 1 (Th1) and T-helper 2 (Th2) immune responses are of great interest as they may determine the outcome of allergic…”
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P308 Observation of NO pathway in homocystinuria and phenylketonuria (PKU) by Kanzelmeyer, N.K, Tsikas, D, Hartmann, H, Illsinger, S, Das, A.M, Lücke, T

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Vaso-occlusion in Schimke-immuno-osseous dysplasia: is the NO pathway involved? by Lücke, T, Tsikas, D, Kanzelmeyer, N K, Boerkoel, C F, Clewing, J M, Vaske, B, Ehrich, J H H, Das, A M

“…Schimke-immuno-osseous dysplasia (SIOD) is an autosomal recessive disorder with the main clinical findings of spondyloepiphyseal dysplasia, nephrotic syndrome,…”
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Are plasma S-nitrosothiol levels elevated in chronic renal failure? by Tsikas, Dimitrios, Frölich, Jürgen C.

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