Search Results - "Tsezou, A."

Osteoarthritis Year in Review 2014: genetics and genomics by Tsezou, A

“…Summary Recent developments in genetics/genomics of osteoarthritis (OA) are discussed to improve our understanding of OA pathophysiology. The discovery of a…”
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Genetics/genomics in osteoarthritis by Tsezou, A

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Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes by Ntoumou, E, Tzetis, M, Braoudaki, M, Lambrou, G, Poulou, M, Malizos, K, Stefanou, N, Anastasopoulou, L, Tsezou, A

“…MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In this study, we aimed to identify a circulating miRNA signature for osteoarthritis…”
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Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention by Iliopoulos, D, Malizos, K N, Tsezou, A

“…Objective:To investigate whether epigenetic mechanisms can regulate leptin’s expression and affect its downstream targets as metalloproteinases 3,9,13 in…”
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Differential expression of leptin and leptin's receptor isoform (Ob-Rb) mRNA between advanced and minimally affected osteoarthritic cartilage; effect on cartilage metabolism by Simopoulou, T., M.D, Malizos, K.N., M.D., Ph.D, Iliopoulos, D., Ph.D, Stefanou, N., B.Sc, Papatheodorou, L., M.D, Ioannou, M., M.D., Ph.D, Tsezou, A., Ph.D

“…Summary Objective To investigate leptin's effect on cartilage metabolism and the pathophysiology of osteoarthritis (OA). Methods Messenger RNA (mRNA)…”
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Articular cartilage status 2 years after arthroscopic ACL reconstruction in patients with or without concomitant meniscal surgery: evaluation with 3.0T MR imaging by Michalitsis, S., Hantes, M., Thriskos, P., Tsezou, A., Malizos, K. N., Fezoulidis, I., Vlychou, M.

“…Purpose To assess articular cartilage changes in the knee joint as detected on 3.0T MR imaging after 2-year follow-up in patients who underwent arthroscopic…”
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Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes by Rodriguez-Lopez, J., M.Sc, Pombo-Suarez, M., M.D, Loughlin, J., Ph.D, Tsezou, A., Ph.D, Blanco, F.J., M.D., Ph.D, Meulenbelt, I., Ph.D, Slagboom, P.E., Ph.D, Valdes, A.M., Ph.D, Spector, T.D., M.D., M.Sc., FRCP, Gomez-Reino, J.J., M.D., Ph.D, Gonzalez, A., Ph.D., M.D

“…Summary Objective To investigate the effect in OA (Osteoarthritis) susceptibility of putative damaging changes in ADAM (A Disintegrin And Metalloprotease) and…”
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MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux related genes in osteoarthritic chondrocytes by Kostopoulou, F, Malizos, K.N, Papathanasiou, I, Tsezou, A

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Asporin and knee osteoarthritis in patients of Greek origin by Kaliakatsos, M., Tzetis, M., Kanavakis, E., Fytili, P., Chouliaras, G., Karachalios, Th, Malizos, K., Tsezou, A.

“…Ostearthritis (OA) is characterized by focal areas of loss of the articular cartilage in synovial joints, associated with varying degrees of osteophyte…”
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Chorionic villi derived mesenchymal like stem cells and expression of embryonic stem cells markers during long-term culturing by Katsiani, E., Garas, A., Skentou, C., Tsezou, A., Messini, C. I., Dafopoulos, K., Daponte, A., Messinis, I. E.

“…Mesenchymal stem cells (MSCs) can be obtained from a variety of human tissues. MSCs derived from placental chorionic villi of the first trimester are likely to…”
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Deep sequencing of GDF5 reveals the absence of rare variants at this important osteoarthritis susceptibility locus by Dodd, A.W, Rodriguez-Fontenla, C, Calaza, M, Carr, A, Gomez-Reino, J.J, Tsezou, A, Reynard, L.N, Gonzalez, A, Loughlin, J

“…Summary Objective The common single nucleotide polymorphism (SNP) rs143383 in the 5′ untranslated region (5′UTR) of growth and differentiation factor 5 ( GDF5…”
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Involvement of tgf-a, rock1, dock2 and caveolin-1 in osteoarthritis pathogenesis by Papanikolaou, V, Gkretsi, V, Malizos, K, Chatziliadou, E, Dubos, S, Zervakis, M, Kafetzopoulos, D, Kalantzaki, K, Bei, A, Takacs, L, Zoumadakis, C, Tsezou, A

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New functional microsatellite associated with osteoarthritis susceptibility by Vidal-Bralo, L, Rodriguez-Fontela, C, Calaza, M, Oreiro, N, Blanco, F.J, Carr, A, Odriozola, A, Riancho, J, Gomez-Reino, J.J, Tsezou, A, Loughlin, J, Gonzalez, A

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Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1) expression in human articular chondrocytes by SIMOPOULOU, T, MALIZOS, K. N, TSEZOU, A

“…To investigate the involvement of oxidized low density lipoprotein (ox-LDL) and the expression of its receptor lectin-like oxidized low density lipoprotein…”
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189 IMPAIRED EXPRESSION OF GENES INVOLVED IN REVERSE CHOLESTEROL TRANSPORT IN HUMAN OSTEOARTHRITIC CHONDROCYTES: BENEFICIAL EFFECT OF LXR AGONIST TREATMENT by Simopoulou, T, Malizos, K.N, Kostopoulou, F, Tsezou, A

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Use of real-time PCR to detect human papillomavirus-16 viral loads in vaginal and urine self-sampled specimens by Daponte, A., Tsezou, A., Oikonomou, P., Hadjichristodoulou, C., Maniatis, A.N., Pournaras, S., Messinis, I.E.

“…Increasing the accuracy of self-sampling methods to detect oncogenic human papillomavirus (HPV) infection would contribute to the wider application of these…”
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Association of repeat polymorphisms in the estrogen receptors alpha, beta ( ESR1 , ESR2 ) and androgen receptor ( AR ) genes with the occurrence of breast cancer by Tsezou, A, Tzetis, M, Gennatas, C, Giannatou, E, Pampanos, A, Malamis, G, Kanavakis, E, Kitsiou, S

“…Abstract Genetic variation in genes involved in estrogen biosynthesis, metabolism and signal transduction have been suggested to play a role in breast cancer…”
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Contribution of the CFTR gene, the pancreatic secretory trypsin inhibitor gene (SPINK1) and the cationic trypsinogen gene (PRSS1) to the etiology of recurrent pancreatitis by Tzetis, M, Kaliakatsos, M, Fotoulaki, M, Papatheodorou, A, Doudounakis, S, Tsezou, A, Makrythanasis, P, Kanavakis, E, Nousia-Arvanitakis, S

“…Acute recurrent/chronic pancreatitis (CP) is a complex multigenic disease. This is a case–control study consisting of 25 Greek patients with CP and a control…”
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Clinical and molecular description of a fetus in prenatal diagnosis with a rare de novo ring 10 and deletions of 12.59 Mb in 10p15.3–p14 and 4.22 Mb in 10q26.3 by Christopoulou, G, Tzetis, M, Konstantinidou, A.E, Tsezou, A, Kanavakis, E, Kitsiou-Tzeli, S, Velissariou, V

“…Abstract Ring chromosomes are rare cytogenetic findings and are mostly associated with an abnormal phenotype. We report on the prenatal diagnosis of a ring…”
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Real-time quantification of human telomerase reverse transcriptase mRNA in liver tissues from patients with hepatocellular cancer and chronic viral hepatitis by Satra, M., Gatselis, N., Iliopoulos, D., Zacharoulis, D., Dalekos, G. N., Tsezou, A.

“…We determined, for the first time, the human telomerase reverse transcriptase (hTERT) mRNA expression, using real‐time quantitative PCR, in liver tissues from…”
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