Search Results - "Tseng, Jack L"

The BACE1 inhibitor verubecestat (MK-8931) reduces CNS β-amyloid in animal models and in Alzheimer's disease patients by Kennedy, Matthew E, Stamford, Andrew W, Chen, Xia, Cox, Kathleen, Cumming, Jared N, Dockendorf, Marissa F, Egan, Michael, Ereshefsky, Larry, Hodgson, Robert A, Hyde, Lynn A, Jhee, Stanford, Kleijn, Huub J, Kuvelkar, Reshma, Li, Wei, Mattson, Britta A, Mei, Hong, Palcza, John, Scott, Jack D, Tanen, Michael, Troyer, Matthew D, Tseng, Jack L, Stone, Julie A, Parker, Eric M, Forman, Mark S

“…β-Amyloid (Aβ) peptides are thought to be critically involved in the etiology of Alzheimer's disease (AD). The aspartyl protease β-site amyloid precursor…”
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Lentiviral Vectors as a Gene Delivery System in the Mouse Midbrain: Cellular and Behavioral Improvements in a 6-OHDA Model of Parkinson's Disease Using GDNF by Bensadoun, Jean-Charles, Déglon, Nicole, Tseng, Jack L., Ridet, Jean-Luc, Zurn, Anne D., Aebischer, Patrick

“…Local delivery of therapeutic molecules represents one of the limiting factors for the treatment of neurodegenerative disorders. In vivo gene transfer using…”
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GDNF Reduces Drug-Induced Rotational Behavior after Medial Forebrain Bundle Transection by a Mechanism Not Involving Striatal Dopamine by Tseng, Jack L, Baetge, E. Edward, Zurn, Anne D, Aebischer, Patrick

“…Parkinson's disease (PD) is characterized by the progressive loss of the substantia nigra (SN) dopaminergic neurons projecting to the striatum. Neurotrophic…”
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Comparative study of GDNF delivery systems for the CNS: polymer rods, encapsulated cells, and lentiviral vectors by Bensadoun, Jean-Charles, Pereira de Almeida, Luis, Fine, Eric G, Tseng, Jack L, Déglon, Nicole, Aebischer, Patrick

“…Glial cell line-derived neurotrophic factor (GDNF) holds great promise for the treatment of Parkinson’s disease. In humans, its intracerebroventricular…”
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468 ASSESSMENT OF KAN-101 IN CED AND IMMUNE TOLERANCE (ACED-IT) STUDY, PH1B DATA WITH HIGHER DOSE LEVELS OF KAN-101, A NOVEL IMMUNE TOLERANCE THERAPY FOR CELIAC DISEASE by Tseng, Jack L., Morgan, Stephanie, Wassaf, Dina, Ramakrishna, Jyoti, Karanam, Ashwin, Hassanein, Mohamed, Treem, William, Thornley, Tom, Grebe, Kristie M.

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Neurturin protects dopaminergic neurons following medial forebrain bundle axotomy by Tseng, Jack L, Bruhn, Suzanne L, Zurn, Anne D, Aebischer, Patrick

“…TO determine whether neurturin (NTN), a recently identified homologue of glial cell line-derived neurotrophic factor (GDNF), is able to preserve tyrosine…”
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Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease by Déglon, N, Tseng, J L, Bensadoun, J C, Zurn, A D, Arsenijevic, Y, Pereira de Almeida, L, Zufferey, R, Trono, D, Aebischer, P

“…Glial cell line-derived neurotrophic factor (GDNF) is able to protect dopaminergic neurons against various insults and constitutes therefore a promising…”
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Seizure Suppression in Kindled Rats by Intraventricular Grafting of an Adenosine Releasing Synthetic Polymer by Boison, Detlev, Scheurer, Louis, Tseng, Jack L., Aebischer, Patrick, Mohler, Hanns

“…Adenosine, an endogenous inhibitory neuromodulator in the central nervous system, exerts anticonvulsant activity that is largely based on the inhibition of the…”
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Encapsulated neural transplants by Tseng, J L, Aebischer, P

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A STUDY OF RESIDENT PARTICIPATION IN COMMUNITY DEVELOPMENT PROGRAMS IN TAIWAN by LI, TSENG-LU JACK

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