Search Results - "Tsen, M F"

IL-1 Receptor-Associated Kinase Modulates Host Responsiveness to Endotoxin by Swantek, Jennifer L, Tsen, May F, Cobb, Melanie H, Thomas, James A

“…Endotoxin triggers many of the inflammatory, hemodynamic, and hematological derangements of Gram-negative septic shock. Recent genetic studies in mice have…”
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Abnormally short serum half-lives of IgG in beta 2-microglobulin-deficient mice by Ghetie, V, Hubbard, J G, Kim, J K, Tsen, M F, Lee, Y, Ward, E S

“…The MHC class I-related receptor, FcRn, mediates the transfer of maternal gamma globulin (IgG) to young rodents, primarily via intestinal transcytosis, and…”
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IL-1 Receptor-Associated Kinase 1 Regulates Susceptibility to Organ-Specific Autoimmunity by Deng, Caishu, Radu, Caius, Diab, Asim, Tsen, May F, Hussain, Rehana, Cowdery, John S, Racke, Michael K, Thomas, James A

“…Infections often precede the development of autoimmunity. Correlation between infection with a specific pathogen and a particular autoimmune disease ranges…”
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Localization of the site of the murine IgG1 molecule that is involved in binding to the murine intestinal Fc receptor by Kim, J K, Tsen, M F, Ghetie, V, Ward, E S

“…Site-directed mutagenesis of a recombinant Fc hinge fragment has recently been used to localize the site of the murine IgG1 molecule that is involved in the…”
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Identifying amino acid residues that influence plasma clearance of murine IgG1 fragments by site-directed mutagenesis by Kim, J K, Tsen, M F, Ghetie, V, Ward, E S

“…Site-directed mutagenesis has been used to change amino acid residues of a recombinant Fc-hinge fragment derived from the murine immunoglobulin (Ig)G1…”
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Catabolism of the murine IgG1 molecule: evidence that both CH2-CH3 domain interfaces are required for persistence of IgG1 in the circulation of mice by Kim, J K, Tsen, M F, Ghetie, V, Ward, E S

“…Site-directed mutagenesis of a recombinant Fc-hinge fragment has previously been used to identify a region of the murine IgG1 molecule that controls…”
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Evidence that the hinge region plays a role in maintaining serum levels of the murine IgG1 molecule by Kim, Jin-Kyoo, Tsen, May-Fang, Ghetie, Victor, Sally Ward, E.

“…The site of the murine IgG1 molecule that regulates catabolism has recently been shown to encompass amino acids that are located at the CH2CH3 domain…”
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IRAK1 deletion disrupts cardiac Toll/IL-1 signaling and protects against contractile dysfunction by Thomas, James A, Haudek, Sandra B, Koroglu, Tolga, Tsen, May F, Bryant, Debora D, White, D Jean, Kusewitt, Donna F, Horton, Jureta W, Giroir, Brett P

“…Myocardial contractile dysfunction accompanies both systemic and cardiac insults. Septic shock and burn trauma can lead to reversible contractile deficits,…”
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Bone marrow-derived cells contribute to contractile dysfunction in endotoxic shock by Binck, Brian W, Tsen, May F, Islas, Miguel, White, D Jean, Schultz, Roger A, Willis, Monte S, Garcia, J Victor, Horton, Jureta W, Thomas, James A

“…How infection precipitates depressed contractility is incompletely understood but may involve the immune, nervous, and endocrine systems as well as the heart…”
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TLR4 inactivation and rBPI(21) block burn-induced myocardial contractile dysfunction by Thomas, James A, Tsen, May F, White, D Jean, Horton, Jureta W

“…Both large burns and severe gram-negative sepsis are associated with acute myocardial contractile dysfunction. Because others have reported that burn injury…”
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IRAK contributes to burn-triggered myocardial contractile dysfunction by Thomas, James A, Tsen, May F, White, D Jean, Horton, Jureta W

“…Major burn injury causes myocardial contractile dysfunction, but the molecular basis of this physiological response is incompletely understood. Previous…”
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