Search Results - "Tsen, Fred"
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Secreted heat shock protein-90 (Hsp90) in wound healing and cancer
Published in Biochimica et biophysica acta (01-03-2012)“…Extracellular Hsp90 proteins, including “membrane-bound”, “released” and “secreted”, were first reported more than two decades ago. Only studies of the past…”
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Journal Article -
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Extracellular Heat Shock Protein 90 Signals through Subdomain II and the NPVY Motif of LRP-1 Receptor to Akt1 and Akt2: a Circuit Essential for Promoting Skin Cell Migration In Vitro and Wound Healing In Vivo
Published in Molecular and Cellular Biology (01-12-2013)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Journal Article -
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Identification of the critical therapeutic entity in secreted Hsp90α that promotes wound healing in newly re-standardized healthy and diabetic pig models
Published in PloS one (02-12-2014)“…Chronic and non-healing skin wounds represent a significant clinical, economic and social problem worldwide. Currently, there are few effective treatments…”
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Journal Article -
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Extracellular Hsp90 (eHsp90) as the actual target in clinical trials: intentionally or unintentionally
Published in International review of cell and molecular biology (2013)“…Despite extensive investigative studies and clinical trials over the past two decades, we still do not understand why cancer cells are more sensitive to the…”
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Journal Article -
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A fragment of secreted Hsp90α carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice
Published in The Journal of clinical investigation (01-11-2011)“…Wounds that fail to heal in a timely manner, for example, diabetic foot ulcers, pose a health, economic, and social problem worldwide. For decades,…”
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Journal Article -
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Identification of the Critical Therapeutic Entity in Secreted Hsp90[alpha] That Promotes Wound Healing in Newly Re-Standardized Healthy and Diabetic Pig Models
Published in PloS one (02-12-2014)“…Chronic and non-healing skin wounds represent a significant clinical, economic and social problem worldwide. Currently, there are few effective treatments…”
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Journal Article -
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A potentially common peptide target in secreted heat shock protein-90α for hypoxia-inducible factor-1α-positive tumors
Published in Molecular biology of the cell (15-02-2012)“…Deregulated accumulation of hypoxia-inducible factor-1α (HIF-1α) is a hallmark of many solid tumors. Directly targeting HIF-1α for therapeutics is challenging…”
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Journal Article -
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A fragment of secreted Hsp90[alpha] carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice
Published in The Journal of clinical investigation (01-11-2011)“…Wounds that fail to heal in a timely manner, for example, diabetic foot ulcers, pose a health, economic, and social problem worldwide. For decades,…”
Get full text
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Gene expression in the tuberculous granuloma: analysis by laser capture microdissection and real‐time PCR
Published in Cellular microbiology (01-07-2003)“…Summary We have assessed the kinetics of host gene expression in granulomas of mice infected with virulent Mycobacterium tuberculosis, using an approach that…”
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Journal Article -
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Extracellular Hsp90 (eHsp90) as the Actual Target in Clinical Trials
Published in International Review of Cell and Molecular Biology (2013)“…Despite extensive investigative studies and clinical trials over the past two decades, we still do not understand why cancer cells are more sensitive to the…”
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Book Chapter -
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The mechanism by which extracellular Hsp90α Promotes cell migration: Implications in wound healing and cancer progression
Published 01-01-2013“…Extracellular heat shock protein-90 (eHsp90) proteins, which include the membrane-bound, released and secreted forms were first cited in scientific literature…”
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Dissertation