Search Results - "Tse, T. E"
-
1
Deletion of a single mevalonate kinase (Mvk) allele yields a murine model of hyper-IgD syndrome
Published in Journal of inherited metabolic disease (01-11-2007)“…In the current study our objective was to develop a murine model of human hyper-IgD syndrome (HIDS) and severe mevalonic aciduria (MA), autoinflammatory…”
Get full text
Journal Article -
2
A Uniform Extracellular Stimulus Triggers Distinct cAMP Signals in Different Compartments of a Simple Cell
Published in Proceedings of the National Academy of Sciences - PNAS (06-11-2001)“…cAMP, the classical second messenger, regulates many diverse cellular functions. The primary effector of cAMP signals, protein kinase A, differentially…”
Get full text
Journal Article -
3
Evening dosing versus morning dosing of antihypertensive medications for nocturnal hypertension: a systematic review and meta-analysis of 107 randomized controlled trials
Published in Journal of hypertension (01-10-2024)“…Since the effects of once-daily antihypertensive (HT) medications are more pronounced within the first few hours of ingestion, evening administration of…”
Get full text
Journal Article -
4
Change in framingham cardiovascular disease risk between 2003 and 2014 in the hong kong population health survey
Published in European heart journal (12-10-2021)“…Abstract Background The Framingham Risk model estimates a person's 10-year cardiovascular disease (CVD) risk. Purpose We aimed to calculate the change in…”
Get full text
Journal Article -
5
Changes in cardiovascular disease risk predicted by the Framingham risk model in the Hong Kong population between 2003-2005 and 2014-2015: data from Population Health Surveys
Published in Hong Kong medical journal = Xianggang yi xue za zhi (01-06-2024)“…The Framingham risk model estimates a person's 10-year cardiovascular disease (CVD) risk. This study used this model to calculate the changes in sex- and…”
Get full text
Journal Article -
6
Abstract P2-06-15: Rational combination of Wee1 and BCL-2 inhibition in preclinical models of triple-negative breast cancer
Published in Cancer research (Chicago, Ill.) (15-02-2019)“…Abstract Background: Triple-negative breast cancer (TNBC) is an aggressive subtype distinguished by its lack of expression of receptors for estrogen,…”
Get full text
Journal Article -
7
In vivo assessment of local phosphodiesterase activity using tailored cyclic nucleotide-gated channels as cAMP sensors
Published in The Journal of general physiology (01-07-2001)“…Phosphodiesterases (PDEs) catalyze the hydrolysis of the second messengers cAMP and cGMP. However, little is known about how PDE activity regulates cyclic…”
Get full text
Journal Article -
8
Long-Term K+ Channel-Mediated Dampening of Dopamine Neuron Excitability by the Antipsychotic Drug Haloperidol
Published in The Journal of neuroscience (26-11-2003)“…Antipsychotic drugs require days of treatment to begin to produce therapeutic effects. We report that in vivo treatment with the antipsychotic drug haloperidol…”
Get full text
Journal Article -
9
Laparoscopic nephrectomy: the learning-curve experience
Published in Canadian Journal of Surgery (01-04-1994)“…To report the learning-curve experience with laparoscopic nephrectomy. Case series. A tertiary-care referral centre serving southern Saskatchewan. Sixteen…”
Get full text
Journal Article -
10
Parameter identification criteria for salt brine dispersion from desalination plant ocean outfalls
Published in IEEE 1971 Conference on Engineering in the Ocean Environment (1971)“…Simulation of large-scale pollution problems is most often subject to identification of important physical constants. Moreover, the inherent randomness of the…”
Get full text
Conference Proceeding -
11
Hyperfine and Nuclear Quadrupole Interactions in Copper-Doped Ti O 2
Published in Physical review (01-12-1969)Get full text
Journal Article