Search Results - "Tschirhart, E J"

STIM1 but not STIM2 is an essential regulator of Ca2+ influx-mediated NADPH oxidase activity in neutrophil-like HL-60 cells by Bréchard, S., Plançon, S., Melchior, C., Tschirhart, E.J.

“…STIM1, not STIM2, regulates Ca2+ influx-mediated NADPH oxidase activity in neutrophil-like HL-60 cells. Extracellular Ca2+ entry, primarily mediated through…”
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Store-operated Ca2+ channels formed by TRPC1, TRPC6 and Orai1 and non-store-operated channels formed by TRPC3 are involved in the regulation of NADPH oxidase in HL-60 granulocytes by Bréchard, S, Melchior, C, Plançon, S, Schenten, V, Tschirhart, E.J

“…Summary Ca2+ influx has been shown to be essential for NADPH oxidase activity which is involved in the inflammatory process. Ca2+ conditions underlying the…”
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Pertussis toxin-sensitive G(i)-proteins and intracellular calcium sensitivity of vasoconstriction in the intact rat tail artery by Spitzbarth-Régrigny, E, Petitcolin, M A, Bueb, J L, Tschirhart, E J, Atkinson, J, Capdeville-Atkinson, C

“…1. We studied the involvement of pertussis toxin (PTX)-sensitive G-proteins in the sensitivity of arterial constriction to intracellular calcium ([Ca(2+)](i))…”
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Human umbilical cord blood monocyte-derived eosinophils produce superoxide but not nitric oxide by Zardini, D M, Tschirhart, E J

“…To investigate whether in vitro derived eosinophils release nitric oxide (NO), whose role in the pathogenesis of asthma is under intense debate. Human…”
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Endothelins: functional and autoradiographic studies in guinea pig trachea by Tschirhart, E J, Drijfhout, J W, Pelton, J T, Miller, R C, Jones, C R

“…The presence of binding sites for [125I]endothelin-1 and the contractile activities of endothelins (ETs) and sarafotoxin S6b and the endothelin fragment…”
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Interleukin-8 primes oxidative burst in neutrophil-like HL-60 through changes in cytosolic calcium by Bréchard, S., Bueb, J.-L., Tschirhart, E.J.

“…In response to a variety of stimuli, neutrophils release large amount of reactive oxygen species (ROS) generated by NADPH oxidase. This process known as the…”
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Receptor-independent effects of natural cannabinoids in rat peritoneal mast cells in vitro by Bueb, Jean-Luc, Lambert, Didier M., Tschirhart, Eric J.

“…Cannabinoids can activate CB 1 and CB 2 receptors. Since a CB 2 mRNA has been described in rat peritoneal mast cells (RPMC), we investigated a series of…”
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Modulation by cADPr of Ca2+ mobilization and oxidative response in dimethylsulfoxide- or retinoic acid-differentiated HL-60 cells by Bréchard, S, Brunello, A, Bueb, J-L, Tschirhart, E J

“…In human phagocytic cells, reactive oxygen species (ROS) generation in response to N-formyl-L-Methionyl-L-Leucyl-L-Phenylalanine (fMLF) is largely dependent on…”
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Release of O2–by human umbilical cord blood-derived eosinophils: role of intra- and extracellular calcium by Zardini, D.M., Bueb, J.-L., Tschirhart, E.J.

“…The aim of our study was to investigate the physiologic mechanisms involved in eosinophil activation as an essential prerequisite to disrupting the biochemical…”
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Pertussis toxin‐sensitive Gi‐proteins and intracellular calcium sensitivity of vasoconstriction in the intact rat tail artery by Spitzbarth‐Régrigny, E, Petitcolin, M ‐A, Bueb, J ‐L, Tschirhart, E J, Atkinson, J, Capdeville‐Atkinson, C

“…We studied the involvement of pertussis toxin (PTX)‐sensitive G‐proteins in the sensitivity of arterial constriction to intracellular calcium ([Ca2+]i)…”
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OAG induces an additional PKC-, PI3K-, and Rac2-mediated signaling pathway up-regulating NOX2 activity, independently of Ca super(2+) entry by Brechard, S, Salsmann, A, Tschirhart, E J

“…The requirement of calcium ion (Ca super(2+)) entry for neutrophil NADPH oxidase (NOX2) regulation is clearly established. However, its role in the signaling…”
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STIM1 but not STIM2 is an essential regulator of Ca super(2+) influx-mediated NADPH oxidase activity in neutrophil-like HL-60 cells by Brechard, S, Plancon, S, Melchior, C, Tschirhart, E J

“…Extracellular Ca super(2+) entry, primarily mediated through store-operated Ca super(2+) entry (SOCE), is known to be a critical event for NADPH oxidase (NOX2)…”
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Pertussis toxin‐sensitive G i ‐proteins and intracellular calcium sensitivity of vasoconstriction in the intact rat tail artery by Spitzbarth‐Régrigny, E, Petitcolin, M ‐A, Bueb, J ‐L, Tschirhart, E J, Atkinson, J, Capdeville‐Atkinson, C

“…We studied the involvement of pertussis toxin (PTX)‐sensitive G‐proteins in the sensitivity of arterial constriction to intracellular calcium ([Ca 2+ ] i )…”
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Store-operated Ca super(2) super(+) channels formed by TRPC1, TRPC6 and Orai1 and non-store-operated channels formed by TRPC3 are involved in the regulation of NADPH oxidase in HL-60 granulocytes by Brechard, S, Melchior, C, Plancon, S, Schenten, V, Tschirhart, E J

“…Ca super(2) super(+) influx has been shown to be essential for NADPH oxidase activity which is involved in the inflammatory process. Ca super(2) super(+)…”
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Binding characteristics of [125I]endothelin-1 in guinea-pig trachea and its displacement by endothelin-1, endothelin-3 and endothelin (16-21) by Tschirhart, E J, Pelton, J T, Jones, C R

“…The presence of binding sites for endothelin-1 (ET-1) and endothelin-3 (ET-3) in airway epithelium, submucosa and smooth muscle of guinea-pig trachea was…”
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Release of 0 sub(2) super(-) by human umbilical cord blood-derived eosinophils: role of intra- and extracellular calcium by Zardini, D M, Bueb, J-L, Tschirhart, E J

“…The aim of our study was to investigate the physiologic mechanisms involved in eosinophil activation as an essential prerequisite to disrupting the biochemical…”
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Pertussis toxin-sensitive G sub(i)-proteins and intracellular calcium sensitivity of vasoconstriction in the intact rat tail artery by Spitzbarth-Regrigny, E, Petitcolin, M-A, Bueb, J-L, Tschirhart, E J, Atkinson, J, Capdeville-Atkinson, C

“…We studied the involvement of pertussis toxin (PTX)-sensitive G-proteins in the sensitivity of arterial constriction to intracellular calcium ([Ca super(2+)]…”
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Selective differentiation and proliferation of human eosinophils from umbilical cord blood: calcium fluxes and superoxide ion secretion by Zardini, D M, Tschirhart, E J

“…Investigation of the physiologic mechanisms involved in the activation of eosinophils is crucial to comprehend their role in the pathogenesis of allergic…”
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Analogues and homologues of N-palmitoylethanolamide, a putative endogenous CB2 cannabinoid, as potential ligands for the cannabinoid receptors by Lambert, Didier M, DiPaolo, Federica G, Sonveaux, Pierre, Kanyonyo, Martial, Govaerts, Sophie J, Hermans, Emmanuel, Bueb, Jean-Luc, Delzenne, Nathalie M, Tschirhart, Eric J

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Human umbilical cord blood-derived eosinophils cultured in the presence of IL-3 and IL-5 respond to fMLP with [Ca super(2+)] sub(i) variation and O sub(2) super(-) production by Zardini, D M, Heuschling, P, Gallois, A, Bueb, J-L, Tschirhart, E J

“…In the presence of interleukin-3 and interleukin-5, eosinophil precursors from human umbilical cord blood mononuclear cells were regularly differentiated into…”
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