Search Results - "Tschank, Georg"

In vitro metabolic and mitogenic signaling of insulin glargine and its metabolites by Sommerfeld, Mark R, Müller, Günter, Tschank, Georg, Seipke, Gerhard, Habermann, Paul, Kurrle, Roland, Tennagels, Norbert

“…Insulin glargine (Lantus) is a long-acting basal insulin analog that demonstrates effective day-long glycemic control and a lower incidence of hypoglycemia…”
Get full text

Effect of insulin analogues on insulin/IGF1 hybrid receptors: increased activation by glargine but not by its metabolites M1 and M2 by Pierre-Eugene, Cécile, Pagesy, Patrick, Nguyen, Tuyet Thu, Neuillé, Marion, Tschank, Georg, Tennagels, Norbert, Hampe, Cornelia, Issad, Tarik

“…In diabetic patients, the pharmacokinetics of injected human insulin does not permit optimal control of glycemia. Fast and slow acting insulin analogues have…”
Get full text

1,1-Dioxo-5,6-dihydro-[4,1,2]oxathiazines, a novel class of 11ß-HSD1 inhibitors for the treatment of diabetes by Böhme, Thomas, Engel, Christian K., Farjot, Géraldine, Güssregen, Stefan, Haack, Torsten, Tschank, Georg, Ritter, Kurt

“…Racemic cis-1,1-dioxo-5,6-dihydro-[4,1,2]oxathiazine derivative 4a was isolated as an impurity in a sample of a hit from a HTS campaign on 11β-hydroxysteroid…”
Get full text

Selective inhibition of hepatic collagen accumulation in experimental liver fibrosis in rats by a new prolyl 4‐hydroxylase inhibitor by Bickel, Martin, Baringhaus, Karl‐Heinz, Gerl, Martin, Günzler, Volkmar, Kanta, Jiri, Schmidts, Ludwig, Stapf, Michael, Tschank, Georg, Weidmann, Klaus, Werner, Ulrich

“…Fibrosis and cirrhosis of the liver are often the result of chronic liver damage by a variety of different agents. Pathological accumulation of collagen,…”
Get full text

1,1-Dioxo-5,6-dihydro-[4,1,2]oxathiazines, a novel class of 11s-HSD1 inhibitors for the treatment of diabetes by Bohme, Thomas, Engel, Christian K, Farjot, Geraldine, Guessregen, Stefan, Haack, Torsten, Tschank, Georg, Ritter, Kurt

“…Racemic cis-1,1-dioxo-5,6-dihydro-[4,1,2]oxathiazine derivative 4a was isolated as an impurity in a sample of a hit from a HTS campaign on 11 beta…”
Get full text

Isolation and Characterization of a 60-70-kD Plasma Membrane Glycoprotein Involved in the Contact-Dependent Inhibition of Growth by Wieser, Raimund J., Schütz, Sonja, Tschank, Georg, Thomas, Helmut, Dienes, Hans-Peter, Oesch, Franz

“…Previous studies have shown that plasma membrane compounds are involved in the contact-dependent inhibition of growth of human diploid fibroblasts. The…”
Get full text

Iron-dependent uptake of ascorbate into isolated microsomes by Peterkofsky, B, Tschank, G, Luedke, C

“…A preliminary study (J.M. Mata, R. Assad, and B. Peterkofsky (1981) Arch. Biochem. Biophys. 206, 93-104) suggested that chick embryo limb bone microsomes took…”
Get more information

The effectiveness of inhibitors of soluble prolyl hydroxylase against the enzyme in the cisternae of isolated bone microsomes by Tschank, G, Hanauske-Abel, H M, Peterkofsky, B

“…Inhibitors of purified, soluble prolyl hydroxylase (K. Majamaa et al. (1984) Eur. J. Biochem. 138, 239-245; K. Majamaa et al. (1986) J. Biol. Chem. 261,…”
Get more information

Effects of hydrazyl group containing drugs on leucocyte functions: an immunoregulatory model for the hydralazine-induced lupus-like syndrome by Schopf, R E, Hanauske-Abel, H M, Tschank, G, Schulte-Wissermann, H, Günzler, V

“…Isoniazid (INH) and hydralazine (HYD) are transglutaminase (TGase, E.C.2.3.2.13.) substrates containing catalytically recruitable hydrazyl groups. Since they…”
Get more information