New Bioactive Chalcones in Propolis from El Salvador

2′,3′-Dihydroxy-4,4′-dimethoxychalcone (1) and 2′,3′,4-trihydroxy-4′-methoxy-chalcone, two new chalcones, were isolated from propolis from El Salvador. The compounds showed significant antibacterial ana antifunfag activity and moderate toxicity to Artemia salina nauplii

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Bibliographic Details
Published in:	Zeitschrift für Naturforschung C. A journal of biosciences Vol. 56; no. 7; pp. 593 - 596
Main Authors:	Popova, Milena, Bankova, Vassya, Spassov, Stefan, Tsvetkova, Iva, Vides Silva, Mario, Tsartsarova, Maria, Naydenski, Christo
Format:	Journal Article
Language:	English
Published:	Germany Verlag der Zeitschrift für Naturforschung 01-07-2001
Subjects:	Animals Anti-Bacterial Agents Anti-Infective Agents - chemistry Anti-Infective Agents - isolation & purification Anti-Infective Agents - pharmacology Antibacterial and Antifungal Activity Antifungal Agents - chemistry Antifungal Agents - isolation & purification Antifungal Agents - pharmacology Artemia Caffeic Acids - toxicity Candida albicans - drug effects Chalcone - chemistry Chalcone - isolation & purification Chalcone - toxicity Chalcones Chromatography, Thin Layer El Salvador El Salvador Propolis Escherichia coli - drug effects Magnetic Resonance Spectroscopy Microbial Sensitivity Tests Models, Molecular Molecular Conformation Molecular Structure Propiophenones - chemistry Propiophenones - isolation & purification Propiophenones - toxicity Propolis - chemistry Staphylococcus aureus - drug effects El Salvador
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Description
Summary:	2′,3′-Dihydroxy-4,4′-dimethoxychalcone (1) and 2′,3′,4-trihydroxy-4′-methoxy-chalcone, two new chalcones, were isolated from propolis from El Salvador. The compounds showed significant antibacterial ana antifunfag activity and moderate toxicity to Artemia salina nauplii
ISSN:	0939-5075 1865-7125
DOI:	10.1515/znc-2001-7-819