Proton magnetic resonance study of the changes in blood lipids in malignant and benign neoplasms

High-resolution 1H-NMR spectrometry (360 MHz) was used in combination with thin layer chromatography to study changes in composition and molecular structure of inverted micelles of blood lipids from patients with breast and uterus cancer. Changes in relative intensity of NMR signals of lipids compar...

Full description

Saved in:

Bibliographic Details
Published in:	Biofizika Vol. 44; no. 4; p. 731
Main Authors:	Katrikadze, N G, Tsarpidze, M A, Dzhishkariani, O S, Sibel'dina, L A, Bochorishvili, I A
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-07-1999
Subjects:	Breast Neoplasms - blood Breast Neoplasms - classification Female Humans Lipids - blood Magnetic Resonance Spectroscopy Micelles Protons Uterine Neoplasms - blood Uterine Neoplasms - classification
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	High-resolution 1H-NMR spectrometry (360 MHz) was used in combination with thin layer chromatography to study changes in composition and molecular structure of inverted micelles of blood lipids from patients with breast and uterus cancer. Changes in relative intensity of NMR signals of lipids compared with norm were revealed. The changes in the lipid composition of blood components, in particular, in cholesterol content, determine the differences in structure and molecular mobility of these lipids, which probably explains the regularities observed in the NMR spectra.
ISSN:	0006-3029