Search Results - "Tsarfaty, I"
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Met-induced membrane blebbing leads to amoeboid cell motility and invasion
Published in Oncogene (03-04-2014)“…Met tyrosine kinase has been implicated in tumorigenesis and metastasis; its overexpression and deregulation is often observed in cancer. Although Met's…”
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2
Expression of inducible nitric oxide synthase by neurones following exposure to endotoxin and cytokine
Published in British journal of pharmacology (01-07-1994)“…In the CNS, nitric oxide (NO) has been implicated as both a mediator of neurotoxicity and a neuromodulator. The inducible NO synthase (iNOS), thought to…”
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3
Effect of Candida albicans metabolite(s) on cellular actin
Published in FEMS microbiology letters (24-09-2002)“…The present study describes experiments of the effect of Candida albicans metabolite(s) (arcsf) on cellular actin, and constitutes a continuation of our…”
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4
The met Proto-Oncogene Receptor and Lumen Formation
Published in Science (American Association for the Advancement of Science) (28-08-1992)“…The met proto-oncogene product (Met) and its ligand, hepatocyte growth factor/scatter factor (HGF/SF), have been implicated in cell mitogenic response, cell…”
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5
Cellular actin is affected by interaction with Candida albicans
Published in FEMS microbiology letters (01-08-2000)“…Abstract Attachment of Candida albicans, an important opportunistic pathogen, to host tissues is an initial step in the development of the infection. The…”
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6
Cellular actin is affected by interaction with Candida albicans
Published in FEMS microbiology letters (15-08-2000)“…Attachment of Candida albicans, an important opportunistic pathogen, to host tissues is an initial step in the development of the infection. The events…”
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7
Production and Characterization of Monoclonal Antibodies Identifying Breast Tumor-Associated Antigens
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-1989)“…We have generated a mouse monoclonal antibody (H23) against the retrovirus-like particles (human mammary tumor virus) released in vitro by the human breast…”
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8
Multiple protein forms of the human breast tumor-associated epithelial membrane antigen (EMA) are generated by alternative splicing and induced by hormonal stimulation
Published in Biochemical and biophysical research communications (16-08-1990)“…Cloning and sequencing of epithelial membrane antigen (EMA) has demonstrated the existence of a variable number of tandem repeats (VNTR) flanked by unique…”
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9
Nuclear Retention of ATM at Sites of DNA Double Strand Breaks
Published in The Journal of biological chemistry (12-10-2001)“…The ATM protein kinase mediates a rapid induction of cellular responses to DNA double strand breaks (DSBs). ATM kinase activity is enhanced immediately after…”
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10
Isolation and characterization of an expressed hypervariable gene coding for a breast-cancer-associated antigen
Published in Gene (14-09-1990)“…A human gene and cDNA coding for a breast-cancer-associated antigen (H23Ag) were isolated and characterized. The gene contains two exons and one intron. Part…”
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11
Met-HGF/SF: tumorigenesis, invasion and metastasis
Published in Ciba Foundation symposium (1997)“…Hepatocyte growth factor/scatter factor (HGF/SF) is synthesized by mesenchymal cells and is a paracrine effector of cells, predominantly epithelial, that…”
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12
In search of drug treatment for genetic defects in the DNA damage response: the example of ataxia-telangiectasia
Published in Seminars in cancer biology (01-08-2004)“…Most genetic disorders are severe diseases that cannot be treated. In the majority of them, enzyme and gene therapy can be significantly curtailed by technical…”
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13
In Vivo Direct Molecular Imaging of Early Tumorigenesis and Malignant Progression Induced by Transgenic Expression of GFP-Met
Published in Neoplasia (New York, N.Y.) (01-05-2006)“…The tyrosine kinase receptor Met and its ligand, hepatocyte growth factor/scatter factor (HGF/SF), play an important role in normal developmental processes, as…”
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14
Tumorigenesis induced by coexpression of human hepatocyte growth factor and the human met protooncogene leads to high levels of expression of the ligand and receptor
Published in Cell growth & differentiation (01-07-1993)“…We have previously shown that, in mouse NIH/3T3 cells, it is necessary to coexpress the gene for human hepatocyte growth factor/scatter factor (HGF/SFhu) with…”
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15
Inhibition of human B-cell lymphoma growth by CD40 stimulation
Published in Blood (15-05-1994)“…CD40 is a molecule present on B lymphocyte lineage cells that is important in B-cell differentiation and activation. Signaling through CD40 has been shown to…”
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16
The Met Proto-Oncogene Mesenchymal to Epithelial Cell Conversion
Published in Science (American Association for the Advancement of Science) (07-01-1994)“…Coexpression of the human Met receptor and its ligand, hepatocyte growth factor/scatter factor (HGF/SF), in NIH 3T3 fibroblasts causes the cells to become…”
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17
In vivo molecular imaging of Met tyrosine kinase growth factor receptor activity in normal organs and breast tumors
Published in Cancer research (Chicago, Ill.) (15-06-2001)“…Molecular imaging techniques allow visualization of specific gene products and their physiological processes in living tissues. In this study, we present a new…”
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18
Met expression and sarcoma tumorigenicity
Published in Cancer research (Chicago, Ill.) (15-11-1993)“…The met protooncogene tyrosine kinase receptor (Met) and its ligand, hepatocyte growth factor/scatter factor (HGF/SF), ordinarily constitute a paracrine…”
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19
Dominant negative Met reduces tumorigenicity-metastasis and increases tubule formation in mammary cells
Published in Oncogene (11-05-2000)“…Activation of the Met tyrosine kinase growth factor receptor by its ligand HGF/SF has been shown to increase in vitro invasiveness in epithelial cell lines. To…”
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20
HGF/SF Increases Tumor Blood Volume: A Novel Tool for the In Vivo Functional Molecular Imaging of Met
Published in Neoplasia (New York, N.Y.) (01-05-2006)“…Molecular functional and metabolic imaging allows visualization of disease-causing processes in living organisms. Here we present a new approach for the…”
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