Search Results - "Tsang, Valerie"

Advanced process monitoring and feedback control to enhance cell culture process production and robustness by Zhang, An, Tsang, Valerie Liu, Moore, Brandon, Shen, Vivian, Huang, Yao-Ming, Kshirsagar, Rashmi, Ryll, Thomas

“…ABSTRACT It is a common practice in biotherapeutic manufacturing to define a fixed‐volume feed strategy for nutrient feeds, based on historical cell demand…”
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Fabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels by Tsang, Valerie Liu, Chen, Alice A, Cho, Lisa M, Jadin, Kyle D, Sah, Robert L, DeLong, Solitaire, West, Jennifer L, Bhatia, Sangeeta N

“…We have fabricated a hepatic tissue construct using a multilayer photopatterning platform for embedding cells in hydrogels of complex architecture. We first…”
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Three-dimensional tissue fabrication by Liu Tsang, Valerie, Bhatia, Sangeeta N.

“…In recent years, advances in fabrication technologies have brought a new dimension to the field of tissue engineering. Using manufacturing-based methods and…”
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Development of a scale down cell culture model using multivariate analysis as a qualification tool by Tsang, Valerie Liu, Wang, Angela X., Yusuf-Makagiansar, Helena, Ryll, Thomas

“…In characterizing a cell culture process to support regulatory activities such as process validation and Quality by Design, developing a representative scale…”
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Effects of pH probe lag on bioreactor mixing time estimation by Zhang, An, Tsang, Valerie Liu, Korke-Kshirsagar, Rashmi, Ryll, Thomas

“…•pH probe response time was investigated to correct empirical mixing time measurement.•The corrected mixing time validated bioreactor CFD models.•The impact of…”
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Identifying the differences in mechanisms of mycophenolic acid controlling fucose content of glycoproteins expressed in different CHO cell lines by Zhang, An, Tsang, Valerie Liu, Markely, Lam R., Kurt, Lutfiye, Huang, Yao-Ming, Prajapati, Shashi, Kshirsagar, Rashmi

“…ABSTRACT In the biopharmaceutical industry, glycosylation is a critical quality attribute that can modulate the efficacy of a therapeutic glycoprotein…”
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Photo- and electropatterning of hydrogel-encapsulated living cell arrays by Albrecht, Dirk R, Tsang, Valerie Liu, Sah, Robert L, Bhatia, Sangeeta N

“…Living cells have the potential to serve as sensors, naturally integrating the response to stimuli to generate predictions about cell fate (e.g.,…”
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Omega-3 fatty acids modulate neonatal cytokine response to endotoxin by Espiritu, Michael M, Lin, Hong, Foley, Elizabeth, Tsang, Valerie, Rhee, Eunice, Perlman, Jeffrey, Cunningham-Rundles, Susanna

“…Neonatal immune response is characterized by an uncompensated pro-inflammatory response that can lead to inflammation-related morbidity and increased…”
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Cognitive status and profile validity on the Personality Assessment Inventory (PAI) in offenders with serious mental illness by Matlasz, Tatiana M, Brylski, Jamie L, Leidenfrost, Corey M, Scalco, Matt, Sinclair, Samuel J, Schoelerman, Ronald M, Tsang, Valerie, Antonius, Daniel

“…Cognitive impairment among seriously mentally ill offenders has implications for legal matters (e.g., competency to stand trial), as well as clinical treatment…”
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Fabrication of three-dimensional tissues by Tsang, Valerie Liu, Bhatia, Sangeeta N

“…The goal of tissue engineering is to restore or replace the lost functions of diseased or damaged organs. Ideally, engineered tissues should provide nutrient…”
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Three-dimensional tissue fabrication: Intelligent therapeutics: biomimetic systems and nanotechnology in drug delivery by TSANG, Valerie Liu, BHATIA, Sangeeta N

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Three-dimensional photopatterning of hydrogels containing living cells for hepatic tissue engineering by Tsang, Valerie Liu

“…Tissue engineering seeks to repair, replace or restore tissue function, typically by combining biomaterials and living cells. Techniques for building…”
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A generic growth test method for improving quality control of disposables in industrial cell culture by Horvath, Brian, Tsang, Valerie Liu, Lin, Weimin, Dai, Xiao-Ping, Kunas, Kurt, Frank, Greg

“…Disposable bags are widely used in the biotechnology industry. The two main purposes are to store cell-culture media and to grow cells for inoculum or…”
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