Search Results - "Tsang, Jessica Oi Ling"

Clinical characteristics of unvaccinated or incompletely vaccinated children with neurological manifestations due to SARS‐CoV‐2 Omicron infection by Tso, Winnie Wan‐Yee, Kwan, Mike Yat‐Wah, Kwok, Janette Siu‐Yin, Tsang, Jessica Oi‐Ling, Yip, Cyril Chik‐Yan, Leung, Lok‐Kan, Li, Cuixin, Wang, Yuliang, Chow, Mathew Siu‐Chun, Tsang, Anita Man‐Ching, Chim, Stella, Chow, Chin‐Ying, Ho, Alvin Chi‐Chung, Chan, Sophelia Hoi‐Shan, Tai, Shuk‐Mui, Lee, Wing‐Cheong, Chan, Victor Chi‐Man, Yau, Eric Kin‐Cheong, Sun, Jacquelyne Ka‐Li, Chow, Hei‐Man, Lau, Yu‐Lung, Ip, Patrick, Chan, Jasper Fuk‐Woo

“…Omicron generally causes milder disease than previous strains of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), especially in fully vaccinated…”
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Improved detection of Zika virus RNA in human and animal specimens by a novel, highly sensitive and specific real‐time RT‐PCR assay targeting the 5′‐untranslated region of Zika virus by Chan, Jasper Fuk‐Woo, Yip, Cyril Chik‐Yan, Tee, Kah‐Meng, Zhu, Zheng, Tsang, Jessica Oi‐Ling, Chik, Kenn Ka‐Heng, Tsang, Terance Gi‐Wai, Chan, Chris Chung‐Sing, Poon, Vincent Kwok‐Man, Sridhar, Siddharth, Yin, Feifei, Hung, Ivan Fan‐Ngai, Chau, Sandy Ka‐Yee, Zhang, Anna Jinxia, Chan, Kwok‐Hung, Yuen, Kwok‐Yung

“…Objective and Method We developed and evaluated five novel real‐time RT‐PCR assays targeting conserved regions in the 5′‐untranslated region (5′‐UTR), envelope…”
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Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters by Yuan, Shuofeng, Ye, Zi-Wei, Liang, Ronghui, Tang, Kaiming, Zhang, Anna Jinxia, Lu, Gang, Ong, Chon Phin, Man Poon, Vincent Kwok, Chan, Chris Chung-Sing, Mok, Bobo Wing-Yee, Qin, Zhenzhi, Xie, Yubin, Chu, Allen Wing-Ho, Chan, Wan-Mui, Ip, Jonathan Daniel, Sun, Haoran, Tsang, Jessica Oi-Ling, Yuen, Terrence Tsz-Tai, Chik, Kenn Ka-Heng, Chan, Chris Chun-Yiu, Cai, Jian-Piao, Luo, Cuiting, Lu, Lu, Yip, Cyril Chik-Yan, Chu, Hin, To, Kelvin Kai-Wang, Chen, Honglin, Jin, Dong-Yan, Yuen, Kwok-Yung, Chan, Jasper Fuk-Woo

“…The in vivo pathogenicity, transmissibility, and fitness of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron (B.1.1.529) variant are…”
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Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study by Chu, Hin, Chan, Jasper Fuk-Woo, Yuen, Terrence Tsz-Tai, Shuai, Huiping, Yuan, Shuofeng, Wang, Yixin, Hu, Bingjie, Yip, Cyril Chik-Yan, Tsang, Jessica Oi-Ling, Huang, Xiner, Chai, Yue, Yang, Dong, Hou, Yuxin, Chik, Kenn Ka-Heng, Zhang, Xi, Fung, Agnes Yim-Fong, Tsoi, Hoi-Wah, Cai, Jian-Piao, Chan, Wan-Mui, Ip, Jonathan Daniel, Chu, Allen Wing-Ho, Zhou, Jie, Lung, David Christopher, Kok, Kin-Hang, To, Kelvin Kai-Wang, Tsang, Owen Tak-Yin, Chan, Kwok-Hung, Yuen, Kwok-Yung

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported from China in January, 2020. SARS-CoV-2 is efficiently transmitted from person to…”
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SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters by Qiao, Wei, Lau, Hui En, Xie, Huizhi, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Chu, Hin, Yuan, Shuofeng, Yuen, Terrence Tsz-Tai, Chik, Kenn Ka-Heng, Tsang, Jessica Oi-Ling, Chan, Chris Chun-Yiu, Cai, Jian-Piao, Luo, Cuiting, Yuen, Kwok-Yung, Cheung, Kenneth Man-Chee, Chan, Jasper Fuk-Woo, Yeung, Kelvin Wai-Kwok

“…Extrapulmonary complications of different organ systems have been increasingly recognized in patients with severe or chronic Coronavirus Disease 2019…”
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Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B-NS3 protease inhibitor by Chan, Jasper Fuk-Woo, Chik, Kenn Ka-Heng, Yuan, Shuofeng, Yip, Cyril Chik-Yan, Zhu, Zheng, Tee, Kah-Meng, Tsang, Jessica Oi-Ling, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Lu, Gang, Zhang, Anna Jinxia, Lai, Kin-Kui, Chan, Kwok-Hung, Kao, Richard Yi-Tsun, Yuen, Kwok-Yung

“…Zika virus (ZIKV) infection is associated with congenital malformations in infected fetuses and severe neurological and other systemic complications in adults…”
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A broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge by Zhou, Biao, Zhou, Runhong, Tang, Bingjie, Chan, Jasper Fuk-Woo, Luo, Mengxiao, Peng, Qiaoli, Yuan, Shuofeng, Liu, Hang, Mok, Bobo Wing-Yee, Chen, Bohao, Wang, Pui, Poon, Vincent Kwok-Man, Chu, Hin, Chan, Chris Chung-Sing, Tsang, Jessica Oi-Ling, Chan, Chris Chun-Yiu, Au, Ka-Kit, Man, Hiu-On, Lu, Lu, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok-Yung, Dang, Shangyu, Chen, Zhiwei

“…The strikingly high transmissibility and antibody evasion of SARS-CoV-2 Omicron variants have posed great challenges to the efficacy of current vaccines and…”
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Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19) by Yuan, Shuofeng, Chan, Chris Chun-Yiu, Chik, Kenn Ka-Heng, Tsang, Jessica Oi-Ling, Liang, Ronghui, Cao, Jianli, Tang, Kaiming, Cai, Jian-Piao, Ye, Zi-Wei, Yin, Feifei, To, Kelvin Kai-Wang, Chu, Hin, Jin, Dong-Yan, Hung, Ivan Fan-Ngai, Yuen, Kwok-Yung, Chan, Jasper Fuk-Woo

“…The ongoing Coronavirus Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) signals an urgent need for an…”
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Lipidomic Profiling Reveals Significant Perturbations of Intracellular Lipid Homeostasis in Enterovirus-Infected Cells by Yan, Bingpeng, Zou, Zijiao, Chu, Hin, Chan, Gabriella, Tsang, Jessica Oi-Ling, Lai, Pok-Man, Yuan, Shuofeng, Yip, Cyril Chik-Yan, Yin, Feifei, Kao, Richard Yi-Tsun, Sze, Kong-Hung, Lau, Susanna Kar-Pui, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung

“…Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are the most common causes of hand, foot, and mouth disease. Severe EV-A71 and CV-A16 infections may…”
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In silico structure-based discovery of a SARS-CoV-2 main protease inhibitor by Wen, Lei, Tang, Kaiming, Chik, Kenn Ka-Heng, Chan, Chris Chun-Yiu, Tsang, Jessica Oi-Ling, Liang, Ronghui, Cao, Jianli, Huang, Yaoqiang, Luo, Cuiting, Cai, Jian-Piao, Ye, Zi-Wei, Yin, Feifei, Chu, Hin, Jin, Dong-Yan, Yuen, Kwok-Yung, Yuan, Shuofeng, Chan, Jasper Fuk-Woo

“…The Coronavirus Disease 2019 (COVID-19) pandemic caused by the novel lineage B betacoroanvirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has…”
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Phosphatidic acid phosphatase 1 impairs SARS-CoV-2 replication by affecting the glycerophospholipid metabolism pathway by Yan, Bingpeng, Yuan, Shuofeng, Cao, Jianli, Fung, Kingchun, Lai, Pok-Man, Yin, Feifei, Sze, Kong-Hung, Qin, Zhenzhi, Xie, Yubin, Ye, Zi-Wei, Yuen, Terrence Tsz-Tai, Chik, Kenn Ka-Heng, Tsang, Jessica Oi-Ling, Zou, Zijiao, Chan, Chris Chun-Yiu, Luo, Cuiting, Cai, Jian-Piao, Chan, Kwok-Hung, Chung, Tom Wai-Hing, Tam, Anthony Raymond, Chu, Hin, Jin, Dong-Yan, Hung, Ivan Fan-Ngai, Yuen, Kwok-Yung, Kao, Richard Yi-Tsun, Chan, Jasper Fuk-Woo

“…Viruses exploit the host lipid metabolism machinery to achieve efficient replication. We herein characterize the lipids profile reprogramming in vitro and in…”
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Vemurafenib Inhibits Enterovirus A71 Genome Replication and Virus Assembly by Hu, Bodan, Chik, Kenn Ka-Heng, Chan, Jasper Fuk-Woo, Cai, Jian-Piao, Cao, Hehe, Tsang, Jessica Oi-Ling, Zou, Zijiao, Hung, Yin-Po, Tang, Kaiming, Jia, Lilong, Luo, Cuiting, Yin, Feifei, Ye, Zi-Wei, Chu, Hin, Yeung, Man-Lung, Yuan, Shuofeng

“…Enterovirus A71 (EV-A71) infection is a major cause of hand, foot, and mouth disease (HFMD), which may be occasionally associated with severe neurological…”
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Development of Three-Dimensional Human Intestinal Organoids as a Physiologically Relevant Model for Characterizing the Viral Replication Kinetics and Antiviral Susceptibility of Enteroviruses by Tsang, Jessica Oi-Ling, Zhou, Jie, Zhao, Xiaoyu, Li, Cun, Zou, Zijiao, Yin, Feifei, Yuan, Shuofeng, Yeung, Man-Lung, Chu, Hin, Chan, Jasper Fuk-Woo

“…Enteroviruses are important causes of hand, foot, and mouth disease, respiratory infections, and neurological infections in human. A major hurdle for the…”
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Metabolic Profiling Reveals Significant Perturbations of Intracellular Glucose Homeostasis in Enterovirus-Infected Cells by Zou, Zijiao, Tsang, Jessica Oi-Ling, Yan, Bingpeng, Chik, Kenn Ka-Heng, Chan, Chris Chun-Yiu, Cao, Jianli, Liang, Ronghui, Tang, Kaiming, Yin, Feifei, Ye, Zi-Wei, Chu, Hin, Chan, Jasper Fuk-Woo, Yuan, Shuofeng, Yuen, Kwok-Yung

“…Enterovirus A71 (EV-A71) is a common cause of hand, foot, and mouth disease. Severe EV-A71 infections may be associated with life-threatening neurological…”
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Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs by Chan, Jasper Fuk-Woo, Yip, Cyril Chik-Yan, Tsang, Jessica Oi-Ling, Tee, Kah-Meng, Cai, Jian-Piao, Chik, Kenn Ka-Heng, Zhu, Zheng, Chan, Chris Chung-Sing, Choi, Garnet Kwan-Yue, Sridhar, Siddharth, Zhang, Anna Jinxia, Lu, Gang, Chiu, Kin, Lo, Amy Cheuk-Yin, Tsao, Sai-Wah, Kok, Kin-Hang, Jin, Dong-Yan, Chan, Kwok-Hung, Yuen, Kwok-Yung

“…Zika virus (ZIKV) is unique among human-pathogenic flaviviruses by its association with congenital anomalies and trans-placental and sexual human-to-human…”
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Low Environmental Temperature Exacerbates Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Golden Syrian Hamsters by Chan, Jasper Fuk Woo, Poon, Vincent Kwok Man, Chan, Chris Chung Sing, Chik, Kenn Ka Heng, Tsang, Jessica Oi Ling, Zou, Zijiao, Chan, Chris Chun Yiu, Lee, Andrew Chak Yiu, Li, Can, Liang, Ronghui, Cao, Jianli, Tang, Kaiming, Yuen, Terrence Tsz Tai, Hu, Bingjie, Huang, Xiner, Chai, Yue, Shuai, Huiping, Luo, Cuiting, Cai, Jian Piao, Chan, Kwok Hung, Sridhar, Siddharth, Yin, Feifei, Kok, Kin Hang, Chu, Hin, Zhang, Anna Jinxia, Yuan, Shuofeng, Yuen, Kwok Yung

“…Abstract Background The effect of low environmental temperature on viral shedding and disease severity of Coronavirus Disease 2019 (COVID-19) is uncertain…”
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Targeting papain-like protease for broad-spectrum coronavirus inhibition by Yuan, Shuofeng, Gao, Xiaopan, Tang, Kaiming, Cai, Jian-Piao, Hu, Menglong, Luo, Peng, Wen, Lei, Ye, Zi-Wei, Luo, Cuiting, Tsang, Jessica Oi-Ling, Chan, Chris Chun-Yiu, Huang, Yaoqiang, Cao, Jianli, Liang, Ronghui, Qin, Zhenzhi, Qin, Bo, Yin, Feifei, Chu, Hin, Jin, Dong-Yan, Sun, Ren, Chan, Jasper Fuk-Woo, Cui, Sheng, Yuen, Kwok-Yung

“…The emergence of SARS-CoV-2 variants of concern and repeated outbreaks of coronavirus epidemics in the past two decades emphasize the need for next-generation…”
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The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targeting treatment strategy by Chan, Jasper Fuk-Woo, Zhu, Zheng, Chu, Hin, Yuan, Shuofeng, Chik, Kenn Ka-Heng, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Yip, Cyril Chik-Yan, Zhang, Xi, Tsang, Jessica Oi-Ling, Zou, Zijiao, Tee, Kah-Meng, Shuai, Huiping, Lu, Gang, Yuen, Kwok-Yung

“…Zika virus (ZIKV) is a human-pathogenic flavivirus that has recently emerged as a global public health threat. ZIKV infection may be associated with congenital…”
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Author Correction: SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters by Qiao, Wei, Lau, Hui En, Xie, Huizhi, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Chu, Hin, Yuan, Shuofeng, Yuen, Terrence Tsz-Tai, Chik, Kenn Ka-Heng, Tsang, Jessica Oi-Ling, Chan, Chris Chun-Yiu, Cai, Jian-Piao, Luo, Cuiting, Yuen, Kwok-Yung, Cheung, Kenneth Man-Chee, Chan, Jasper Fuk-Woo, Yeung, Kelvin Wai-Kwok

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Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons by Chan, Jasper Fuk-Woo, Zhang, Anna Jinxia, Chan, Chris Chung-Sing, Yip, Cyril Chik-Yan, Mak, Winger Wing-Nga, Zhu, Houshun, Poon, Vincent Kwok-Man, Tee, Kah-Meng, Zhu, Zheng, Cai, Jian-Piao, Tsang, Jessica Oi-Ling, Chik, Kenn Ka-Heng, Yin, Feifei, Chan, Kwok-Hung, Kok, Kin-Hang, Jin, Dong-Yan, Au-Yeung, Rex Kwok-Him, Yuen, Kwok-Yung

“…Disseminated or fatal Zika virus (ZIKV) infections were reported in immunosuppressed patients. Existing interferon-signaling/receptor-deficient mouse models…”
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