Search Results - "Tsang, Jason C.H."

Single Cell RNA-Sequencing of Pluripotent States Unlocks Modular Transcriptional Variation by Kolodziejczyk, Aleksandra A., Kim, Jong Kyoung, Tsang, Jason C.H., Ilicic, Tomislav, Henriksson, Johan, Natarajan, Kedar N., Tuck, Alex C., Gao, Xuefei, Bühler, Marc, Liu, Pentao, Marioni, John C., Teichmann, Sarah A.

“…Embryonic stem cell (ESC) culture conditions are important for maintaining long-term self-renewal, and they influence cellular pluripotency state. Here, we…”
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Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers by Gao, Xuefei, Tsang, Jason C H, Gaba, Fortis, Wu, Donghai, Lu, Liming, Liu, Pentao

“…The transcription activator-like effectors (TALEs) and the RNA-guided clustered regularly interspaced short palindromic repeat (CRISPR) associated protein…”
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Reprogramming to pluripotency using designer TALE transcription factors targeting enhancers by Gao, Xuefei, Yang, Jian, Tsang, Jason C H, Ooi, Jolene, Wu, Donghai, Liu, Pentao

“…The modular DNA recognition code of the transcription-activator-like effectors (TALEs) from plant pathogenic bacterial genus Xanthomonas provides a powerful…”
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Mass Spectrometry Based Detection of Hemoglobin E Mutation by Allele-Specific Base Extension Reaction by Tsang, Jason C.H, Charoenkwan, Pimlak, Chow, Katherine C.K, Jin, Yongjie, Wanapirak, Chanane, Sanguansermsri, Torpong, Lo, Y.M. Dennis, Chiu, Rossa W.K

“…The specific detection of a minor population of mutant DNA molecules requires methods of high specificity and sensitivity. While the single-allele base…”
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Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamics by Tsang, Jason C. H., Vong, Joaquim S. L., Ji, Lu, Poon, Liona C. Y., Jiang, Peiyong, Lui, Kathy O., Ni, Yun-Bi, To, Ka Fai, Cheng, Yvonne K. Y., Chiu, Rossa W. K., Lo, Yuk Ming Dennis

“…The human placenta is a dynamic and heterogeneous organ critical in the establishment of the fetomaternal interface and the maintenance of gestational…”
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Single-cell transcriptomic reconstruction reveals cell cycle and multi-lineage differentiation defects in Bcl11a-deficient hematopoietic stem cells by Tsang, Jason C H, Yu, Yong, Burke, Shannon, Buettner, Florian, Wang, Cui, Kolodziejczyk, Aleksandra A, Teichmann, Sarah A, Lu, Liming, Liu, Pentao

“…Hematopoietic stem cells (HSCs) are a rare cell type with the ability of long-term self-renewal and multipotency to reconstitute all blood lineages. HSCs are…”
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Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cells by Leung, Cherry S, Yang, Kevin Y, Li, Xisheng, Chan, Vicken W, Ku, Manching, Waldmann, Herman, Hori, Shohei, Tsang, Jason C H, Lo, Yuk Ming Dennis, Lui, Kathy O

“…We have previously reported an antigen-specific protocol to induce transplant tolerance and linked suppression to human embryonic stem cell (hESC)-derived…”
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Quality Materials for Quality Assurance in the Analysis of Liquid Biopsy Samples by Tsang, Jason C H, Chan, K C Allen

“…[...]the analysis of epidermal growth factor receptor (EGFR) mutations in the plasma ofcancer patients suffering from non-small cell lung cancers has been…”
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Glomus Tumor of Sella Turcica With Synaptophysin Expression Mimicking Pituitary Adenoma by Tsang, Jason C. H., Ng, C. S., Fung, C. F., Chan, John K. C., Cheuk, Wah

“…Glomus tumor can rarely arise in the central nervous system as a sella turcica mass. In this article, we report a case of sellar glomus tumor in a female…”
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Single-Stranded DNA Library Preparation Preferentially Enriches Short Maternal DNA in Maternal Plasma by Vong, Joaquim S L, Tsang, Jason C H, Jiang, Peiyong, Lee, Wing-Shan, Leung, Tak Yeung, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis

“…Recent studies have suggested that single-stranded DNA (ssDNA) library preparation can enrich short DNA species from the plasma of healthy individuals, cancer…”
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Circulating nucleic acids in plasma/serum by Tsang, Jason C.H., Dennis Lo, Y.M.

“…Since the discovery of circulating nucleic acids in plasma in 1948, many diagnostic applications have emerged. For example, diagnostic and prognostic…”
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Enrichment of fetal and maternal long cell‐free DNA fragments from maternal plasma following DNA repair by Vong, Joaquim S.L., Jiang, Peiyong, Cheng, Suk‐Hang, Lee, Wing‐Shan, Tsang, Jason C.H., Leung, Tak‐Yeung, Chan, K.C. Allen, Chiu, Rossa W.K., Lo, Y.M. Dennis

“…Objective Cell‐free DNA (cfDNA) fragments in maternal plasma contain DNA damage and may negatively impact the sensitivity of noninvasive prenatal testing…”
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Cellular reprogramming by transcription factor engineering by Tsang, Jason CH, Gao, Xuefei, Lu, Liming, Liu, Pentao

“…Graphical abstract Summary diagram showing the modulation of gene expression by designer transcription factors generated by different platforms. TALE:…”
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