Search Results - "Tsai, Y.L."

In search of nonribosomal nucleolar protein function and regulation by Pederson, Thoru, Tsai, Robert Y.L

“…The life of the nucleolus has proven to be more colorful and multifaceted than had been envisioned a decade ago. A large number of proteins found in this…”
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OC-0167: Advanced left-side breast cancer: does VMAT allow doses of organs at risk to be reduced? by Yu, P.C, Nien, H.H, Wu, C.J, Tsai, Y.L

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multistep, GTP-driven mechanism controlling the dynamic cycling of nucleostemin by Tsai, Robert Y.L, McKay, Ronald D.G

“…Nucleostemin (NS) was identified as a stem cell- and cancer cell-enriched nucleolar protein that controls the proliferation of these cells. Here, we report the…”
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GNL3L stabilizes the TRF1 complex and promotes mitotic transition by Zhu, Qubo, Meng, Lingjun, Hsu, Joseph K, Lin, Tao, Teishima, Jun, Tsai, Robert Y.L

“…Telomeric repeat binding factor 1 (TRF1) is a component of the multiprotein complex "shelterin," which organizes the telomere into a high-order structure. TRF1…”
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EP-1736: The quantitative measurement of liver motion in CT during respiration by Tsai, Y.L, Yu, P.C, Chang, H.C, Chang, C.Y, Fu, P.W, Lin, C.W, Chiu, Y.C, Chi, S.N, Wu, C.J

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A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells by Tsai, Robert Y L, McKay, Ronald D G

“…The unique property of stem cells to self-renew suggests specific mechanisms that regulate their cell-cycle progression. In the present study, we identify a…”
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Nucleostemin prevents telomere damage by promoting PML-IV recruitment to SUMOylated TRF1 by Hsu, Joseph K, Lin, Tao, Tsai, Robert Y L

“…Continuously dividing cells must be protected from telomeric and nontelomeric DNA damage in order to maintain their proliferative potential. Here, we report a…”
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A novel role of nucleostemin in maintaining the genome integrity of dividing hepatocytes during mouse liver development and regeneration by Lin, Tao, Ibrahim, Wessam, Peng, Cheng‐Yuan, Finegold, Milton J., Tsai, Robert Y.L.

“…During liver development and regeneration, hepatocytes undergo rapid cell division and face an increased risk of DNA damage associated with active DNA…”
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Nucleolar modulation of TRF1: A dynamic way to regulate telomere and cell cycle by nucleostemin and GNL3L by Tsai, Robert Y.L.

“…Chromosomal ends are protected by a high-order structure called telomere.  Maintenance of correct telomere length and structure is critically important for the…”
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Tumor-Initiating Function of Nucleostemin-Enriched Mammary Tumor Cells by TAO LIN, LINGJUN MENG, YI LI, TSAI, Robert Y. L

“…Nucleostemin (NS) is highly expressed in normal stem cells and tumors and is upregulated by estradiol in MCF7 breast cancer cells. To investigate the role of…”
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Creating a graft-friendly environment for stem cells in diseased brains by Tsai, Robert Yl

“…Most of the adult CNS lacks regenerative activity in terms of both neuron birth and neurite outgrowth. While this regeneration-unfriendly environment of the…”
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Expression of the iron transporter ferroportin in synaptic vesicles and the blood–brain barrier by Wu, Laura Jui-chen, Leenders, A.G.Miriam, Cooperman, Sharon, Meyron-Holtz, Esther, Smith, Sophia, Land, William, Tsai, Robert Y.L., Berger, Urs V., Sheng, Zu-Hang, Rouault, Tracey A.

“…Iron homeostasis in the mammalian brain is an important and poorly understood subject. Transferrin-bound iron enters the endothelial cells of the blood–brain…”
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Nucleoplasmic mobilization of nucleostemin stabilizes MDM2 and promotes G2-M progression and cell survival by Meng, Lingjun, Lin, Tao, Tsai, Robert Y.L

“…Nucleolar disassembly occurs during mitosis and nucleolar stress, releasing several MDM2-interactive proteins residing in the nucleolus that share the common…”
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GNL3L depletion destabilizes MDM2 and induces p53-dependent G2 M arrest by Meng, L, Hsu, J K, Tsai, R Y L

“…Guanine nucleotide binding protein-like 3-like (GNL3L) is a nucleolar protein and the vertebrate paralogue of nucleostemin (NS). We previously reported that…”
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Multiple controls regulate nucleostemin partitioning between nucleolus and nucleoplasm by Meng, Lingjun, Yasumoto, Hiroaki, Tsai, Robert Y.L

“…Nucleostemin plays an essential role in maintaining the continuous proliferation of stem cells and cancer cells. The movement of nucleostemin between the…”
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A molecular view of stem cell and cancer cell self-renewal by Tsai, Robert Y.L

“…With the recent advances in cell biology and molecular genetics, scientists were able to isolate and culture tissue-specific stem cells from various sources…”
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BAC transgenic expression efficiency: bicistronic versus ATG-fusion strategies by Lin, Tao, Yasumoto, Hiroaki, Tsai, Robert Y.L.

“…Bacterial artificial chromosome (BAC)‐based transgene can be expressed bicistronically with the target gene or fused to its translation start codon. To compare…”
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GNL3L inhibits activity of estrogen-related receptor γ by competing for coactivator binding by Yasumoto, Hiroaki, Meng, Lingjun, Lin, Tao, Zhu, Qubo, Tsai, Robert Y.L

“…Guanine nucleotide binding protein-like 3 (GNL3L) is the closest homologue of a stem cell-enriched factor nucleostemin in vertebrates. They share the same…”
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Plasticity, Niches, and the Use of Stem Cells by Tsai, Robert Y.L, Kittappa, Raja, McKay, Ronald D.G

“…Stem cells possess the ability to self-renew and generate multiple cell types of the tissues in which they reside. Several studies have reported…”
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Fractal fracture of single crystal silicon by Tsai, Y.L., Mecholsky, J.J.

“…The quantitative description of surfaces that are created during the fracture process is one of the fundamental issues in materials science. In this study,…”
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