Search Results - "Tsai, Sarah"

Whole-genome sequencing for identification of Mendelian disorders in critically ill infants: a retrospective analysis of diagnostic and clinical findings by Willig, Laurel K, MD, Petrikin, Josh E, MD, Smith, Laurie D, MD, Saunders, Carol J, PhD, Thiffault, Isabelle, PhD, Miller, Neil A, BA, Soden, Sarah E, MD, Cakici, Julie A, BSN, Herd, Suzanne M, CCRC, Twist, Greyson, MS, Noll, Aaron, MS, Creed, Mitchell, MA, Alba, Patria M, MD, Carpenter, Shannon L, MD, Clements, Mark A, MD, Fischer, Ryan T, MD, Hays, J Allyson, MD, Kilbride, Howard, Prof, McDonough, Ryan J, DO, Rosterman, Jamie L, DO, Tsai, Sarah L, MD, Zellmer, Lee, MS, Farrow, Emily G, PhD, Kingsmore, Stephen F, Prof

“…Summary Background Genetic disorders and congenital anomalies are the leading causes of infant mortality. Diagnosis of most genetic diseases in neonatal and…”
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Variations in Morning Serum Cortisol Levels Based on Sex and Pubertal Status by Jacob, Sarah A, Williams, David D, Boyd, Jennifer, Dileepan, Kavitha, Tsai, Sarah L

“…Patients with suspected adrenal insufficiency undergo screening with a serum morning cortisol level and confirmatory testing with an adrenocorticotropic…”
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SNARE-ing the Reason for Post-Cardiac Surgery Critical Illness-Related Corticosteroid Insufficiency by Diehl, Nicholas, Kibiryeva, Natalia, Marshall, Jennifer, Tsai, Sarah L, Farias, Juan S, Silva-Gburek, Jaime, Erickson, Lori A

“…Critical illness-related corticosteroid insufficiency (CIRCI) can cause hemodynamic instability in neonates after congenital heart surgery with manifestations…”
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Hyperinsulinemic Hypoglycemia and Growth Hormone Deficiency Secondary to 20p11 Deletion by Wee, Erica, Herriges, John, Dileepan, Kavitha, Tsai, Sarah L., Alaimo, Joseph T., Paprocki, Emily

“…Hypoglycemia is concerning for neurological complications in infants and children. Determining the cause of hypoglycemia is essential in providing appropriate…”
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Pharmacokinetic Study of Rucaparib in Patients With Advanced Solid Tumors by Shapiro, Geoffrey I., Kristeleit, Rebecca S., Burris, Howard A., LoRusso, Patricia, Patel, Manish R., Drew, Yvette, Giordano, Heidi, Maloney, Lara, Watkins, Simon, Goble, Sandra, Jaw‐Tsai, Sarah, Xiao, Jim J.

“…The phase 1‐2 study CO‐338‐010 (Study 10; NCT01482715) is evaluating single‐agent rucaparib, a poly(ADP‐ribose) polymerase inhibitor, administered orally to…”
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Design and characterization of a surfactant‐conjugated, long‐acting, balanced GLP‐1/glucagon receptor dual agonist by Nestor, John J., Zhang, Xiaoming, Jaw‐Tsai, Sarah, Parkes, David G., Becker, Cyrus K.

“…Existing candidates for treating non‐alcoholic steatohepatitis (NASH), including glucagon‐like peptide‐1 (GLP‐1) analogs and previous GLP‐1/glucagon receptor…”
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Primary Adrenocortical Insufficiency Case Series: Genetic Etiologies More Common than Expected by Tsai, Sarah L, Green, Jane, Metherell, Lou A, Curtis, Fiona, Fernandez, Bridget, Healey, Ara, Curtis, Joseph

“…Primary adrenal insufficiency (AI) is an important cause of morbidity in children. Our objectives were: (1) to describe the clinical presentation of children…”
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A retrospective review of pituitary MRI findings in children on growth hormone therapy by Tsai, Sarah L., Laffan, Eoghan, Lawrence, Sarah

“…Background Patients with congenital hypopituitarism might have the classic triad of pituitary stalk interruption syndrome, which consists of: (1) an…”
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Evaluation of in vitro absorption, distribution, metabolism, and excretion and assessment of drug-drug interaction of rucaparib, an orally potent poly(ADP-ribose) polymerase inhibitor by Liao, Mingxiang, Jaw-Tsai, Sarah, Beltman, Jeri, Simmons, Andrew D., Harding, Thomas C., Xiao, Jim J.

“…1. The absorption, distribution, metabolism, elimination, and drug-drug interaction (DDI) potential of the poly(ADP-ribose) polymerase (PARP) inhibitor…”
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Reflections on Incorporating a Behavioral Intervention into a Busy Pediatric Subspecialty Clinic by Tsai, Sarah L., MD, Clements, Mark A., MD, PhD, Apodaca, Timothy R., PhD

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Treatment with methimazole in a 3-year-old male with thyroid hormone resistance by Tsai, Sarah L, Ahmet, Alexandra

“…Thyroid hormone resistance syndromes are disorders in which there is decreased end-organ responsiveness to thyroid hormone. Patients typically present with…”
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AZD-3043: a novel, metabolically labile sedative-hypnotic agent with rapid and predictable emergence from hypnosis by Egan, Talmage D, Obara, Shinju, Jenkins, Thomas E, Jaw-Tsai, Sarah S, Amagasu, Shanti, Cook, Daniel R, Steffensen, Scott C, Beattie, David T

“…Propofol can be associated with delayed awakening after prolonged infusion. The aim of this study was to characterize the preclinical pharmacology of AZD-3043,…”
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Central Nervous System Vasculitis With Positive Antithyroid Antibodies in an Adolescent Boy by Tsai, Sarah L., MD, Lewis, Evan C., MD, Sell, Erick, MD, Whiting, Sharon, MD

“…Abstract Hashimoto’s encephalopathy is diagnosed when patients exhibit features of corticosteroid-responsive encephalopathy and positive antithyroid…”
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Morning cortisol levels affected by sex and pubertal status in children and young adults by Tsai, Sarah L, Seiler, Kelly J, Jacobson, Jill

“…Morning cortisol levels are frequently used as screening tests for adrenal insufficiency in both adults and children. Reports differ on the specificity of this…”
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Hyperglycemic hyperosmolar syndrome at the onset of type 2 diabetes mellitus in an adolescent male by Tsai, Sarah L, Hadjiyannakis, Stasia, Nakhla, Meranda

“…Hyperglycemic hyperosmolar state (HHS) is rare in the paediatric population. The diagnosis and management of HHS presents a challenge in paediatric patients…”
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Congenital Growth Hormone Deficiency - A Review with a Focus on Neuroimaging by Tsai, Sarah L, Laffan, Eoghan

“…Growth hormone deficiency is an important cause of short stature in childhood. It is characterised by low growth velocity in childhood and is diagnosed by…”
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Implementing motivational interviewing in a pediatric hospital by Apodaca, Timothy R, Tsai, Sarah L, Miller, Melissa K, Maddux, Michele H, Kennedy, Diane, Trowbridge, Kelly

“…Motivational Interviewing is a collaborative style of communication designed to strengthen a person's own motivation and commitment to change. We report on our…”
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1191-P: Glycemia Does Not Vary in Proximity to Self-Reported Menstrual Cycles in Adolescents with Type 1 Diabetes by McDonough, Ryan, Priebe, Anne-Marie, Hilyard, Tennille, Dileepan, Kavitha, Tsai, Sarah

“…Introduction & Objectives: Menstruation can change the glycemia and insulin needs of individuals living with T1D. Hormonally-induced insulin resistance is…”
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Pharmacokinetics and safety of TBAJ-876, a novel antimycobacterial diarylquinoline, in healthy subjects by Lombardi, Antonio, Pappas, Fran, Nedelman, Jerry, Hickman, Dean, Jaw-Tsai, Sarah, Olugbosi, Morounfolu, Bruinenberg, Paul, Beumont, Maria, Sun, Eugene

“…TBAJ-876, a second-generation diarylquinoline with greater antimycobacterial activity and a potentially better safety profile compared with bedaquiline, is…”
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CP-101,606, an NR2B subunit selective NMDA receptor antagonist, inhibits NMDA and injury induced c-fos expression and cortical spreading depression in rodents by Menniti, Frank S, Pagnozzi, Martin J, Butler, Paul, Chenard, Bertrand L, Jaw-Tsai, Sarah S, Frost White, W

“…(1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol (CP-101,606) is a noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors…”
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