Search Results - "Tsai, Julia"

Microglia limit the expansion of β-amyloid plaques in a mouse model of Alzheimer's disease by Zhao, Ruohe, Hu, Wanling, Tsai, Julia, Li, Wei, Gan, Wen-Biao

“…Microglia are known as resident immune cells in the brain. β-amyloid (Aβ) plaques in the brain of Alzheimer's disease (AD) are surrounded by microglia, but…”
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Hem1 inborn errors of immunity: waving goodbye to coordinated immunity in mice and humans by Christodoulou, Alexandra, Tsai, Julia Y, Suwankitwat, Nutthakarn, Anderson, Andreas, Iritani, Brian M

“…Inborn errors of immunity (IEI) are a group of diseases in humans that typically present as increased susceptibility to infections, autoimmunity,…”
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Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches by Gan, Wen-Biao, Tsai, Julia, Grutzendler, Jaime, Duff, Karen

“…Amyloid plaques are a hallmark of Alzheimer disease, but their importance in its pathogenesis is controversial. By neuronal labeling and transcranial…”
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Acute and Chronic Outcomes of Gas-Bubble Disease in a Colony of African Clawed Frogs (Xenopus laevis) by Tsai, Julia Y, Felt, Stephen A, Bouley, Donna M, Green, Sherril L

“…Gas-bubble disease occurs in aquatic species that are exposed to water that is supersaturated with gases. In February 2007, municipal water supersaturated with…”
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Malaria parasite infection compromises colonization resistance to an enteric pathogen by reducing gastric acidity by Walker, Gregory T, Yang, Guiyan, Tsai, Julia Y, Rodriguez, Jorge L, English, Bevin C, Faber, Franziska, Souvannaseng, Lattha, Butler, Brian P, Tsolis, Renée M

“…Malaria parasite infection weakens colonization resistance against serovar ( ) Typhimurium. Typhimurium is a member of the Enterobacterales, a taxon that…”
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Endoplasmic Reticulum and Trans-Golgi Network Generate Distinct Populations of Alzheimer β -Amyloid Peptides by Greenfield, Jeffrey P., Tsai, Julia, Gouras, Gunnar K., Hai, Bing, Thinakaran, Gopal, Checler, Frederic, Sisodia, Sangram S., Greengard, Paul, Xu, Huaxi

“…The excessive generation and accumulation of 40- and 42-aa β -amyloid peptides (Aβ40/Aβ42) in selectively vulnerable brain regions is a major neuropathological…”
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Patterns of Fluorescent Protein Expression in Scleractinian Corals by Gruber, David F., Kao, Hung-Teh, Janoschka, Stephen, Tsai, Julia, Pieribone, Vincent A.

“…Biofluorescence exists in only a few classes of organisms, with Anthozoa possessing the majority of species known to express fluorescent proteins. Most species…”
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Flexible and Robust Implementations of Multivariate Adaptive Regression Splines Within a Wastewater Treatment Stochastic Dynamic Program by Tsai, Julia C. C., Chen, Victoria C. P.

“…This paper presents an automatic and more robust implementation of multivariate adaptive regression splines (MARS) within the orthogonal array (OA)/MARS…”
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Dynamic Regulation of Fluorescent Proteins from a Single Species of Coral by Kao, Hung-Teh, Sturgis, Shelby, DeSalle, Rob, Tsai, Julia, Davis, Douglas, Gruber, David F, Pieribone, Vincent A

“…To gain a better understanding of the natural function of fluorescent proteins, we have undertaken quantitative analyses of these proteins in a single species…”
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Stochastic Dynamic Programming Formulation for a Wastewater Treatment Decision-Making Framework by Tsai, Julia C.C., Chen, Victoria C.P., Beck, M. Bruce, Chen, Jining

“…In this paper, a decision-making framework (DMF) based on stochastic dynamic programming (SDP) is presented for a wastewater treatment system, consisting of a…”
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Randomized, double‐blind, placebo‐controlled phase 2 study of ganaxolone as add‐on therapy in adults with uncontrolled partial‐onset seizures by Sperling, Michael R., Klein, Pavel, Tsai, Julia

“…Summary Objective To evaluate the efficacy and safety of ganaxolone as adjunctive therapy in adults with uncontrolled partial‐onset seizures despite taking up…”
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Intravenous Administration of Ganaxolone Attenuates Electroencephalographic Seizures in a Diazepam Resistant Model of Status Epilepticus (P4.212) by Saporito, Michael, Tsai, Julia, Patroneva, Albena

“…Abstract only…”
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A Multicenter, Double-Blind, Randomized, Placebo-Controlled Phase 3 Trial to Determine the Efficacy and Safety of Ganaxolone as Adjunctive Therapy for Adults with Drug-Resistant Focal-Onset Seizures (P5.237) by Lappalainen, Jaakko, Tsai, Julia, Amerine, William, Patroneva, Albena

“…Abstract only…”
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Considerations for determining the efficacy of new antiseizure medications in children age 1 month to younger than 2years by French, Jacqueline A, Cleary, Elena, Dlugos, Dennis, Farfel, Gail, Farrell, Kathleen, Gidal, Barry, Grzeskowiak, Caitlin L, Gurrell, Rachel, Harden, Cynthia, Stalvey, Tracy J, Tsai, Julia, Wirrell, Elaine C, Blum, David, Fountain, Nathan

“…ObjectivesDrug treatment for children with epilepsy should, ideally, be governed by evidence from adequate and well‐controlled clinical studies. However, these…”
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Various Dendritic Abnormalities Are Associated with Fibrillar Amyloid Deposits in Alzheimer's Disease by GRUTZENDLER, JAIME, HELMIN, KATHRYN, TSAI, JULIA, GAN, WEN-BIAO

“…:  Dystrophic neurites are associated with fibrillar amyloid deposition in Alzheimer's disease (AD), but the frequency and types of changes in synaptic…”
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Considerations for determining the efficacy of new antiseizure medications in children age 1 month to younger than 2 years by French, Jacqueline A., Cleary, Elena, Dlugos, Dennis, Farfel, Gail, Farrell, Kathleen, Gidal, Barry, Grzeskowiak, Caitlin L., Gurrell, Rachel, Harden, Cynthia, Stalvey, Tracy J., Tsai, Julia, Wirrell, Elaine C., Blum, David, Fountain, Nathan

“…Objectives Drug treatment for children with epilepsy should, ideally, be governed by evidence from adequate and well‐controlled clinical studies. However,…”
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A randomized controlled trial of ganaxolone in posttraumatic stress disorder by Rasmusson, Ann M., Marx, Christine E., Jain, Sonia, Farfel, Gail M., Tsai, Julia, Sun, Xiaoying, Geracioti, Thomas D., Hamner, Mark B., Lohr, James, Rosse, Richard, Summerall, Lanier, Naylor, Jennifer C., Cusin, Cristine, Lang, Ariel J., Raman, Rema, Stein, Murray B.

“…Preclinical and clinical research supports a role for neuroactive steroids in the pathophysiology of posttraumatic stress disorder (PTSD). We investigated…”
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An Investigation of Consumer Brand Choice Behavior Across Different Retail Formats by Wang, Hui-Ming Deanna, Bezawada, Ram, Tsai, Julia C. C.

“…There has been a blurring with respect to the retail formats because of competition and proliferation of different types of formats. In this research, we use a…”
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Ganaxolone Administered Intravenously Prevents Behavioral Seizures and Promotes Survival in the Rat Lithium-Pilocarpine Model of Status Epilepticus (P2.020) by Saporito, Michael, Tsai, Julia, Patroneva, Albena, White, Steve, Metcalf, Cameron, Barker-Haliski, Melissa L.

“…Abstract only…”
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Ganaxolone Administered Intravenously Prevents Behavioral Seizures and Promotes Survival in the Rat Lithium-Pilocarpine Model of Status Epilepticus (I11.003) by Saporito, Michael, Tsai, Julia, Patroneva, Albena, White, Steve, Metcalf, Cameron, Barker-Haliski, Melissa L.

“…Abstract only…”
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