Search Results - "Tsai, Emily J"
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The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability
Published in Nature (London) (04-05-2017)“…Mitochondrial calcium ( m Ca 2+ ) has a central role in both metabolic regulation and cell death signalling, however its role in homeostatic function and…”
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Nucleostemin Rejuvenates Cardiac Progenitor Cells and Antagonizes Myocardial Aging
Published in Journal of the American College of Cardiology (20-01-2015)“…Abstract Background Functional decline in stem cell–mediated regeneration contributes to aging associated with cellular senescence in c-kit+ cardiac progenitor…”
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3
Pressure-Overload–Induced Subcellular Relocalization/Oxidation of Soluble Guanylyl Cyclase in the Heart Modulates Enzyme Stimulation
Published in Circulation research (20-01-2012)“…RATIONALE:Soluble guanylyl cyclase (sGC) generates cyclic guanosine monophophate (cGMP) upon activation by nitric oxide (NO). Cardiac NO–sGC-cGMP signaling…”
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Increased Vasopressin 1A Receptor Expression in Failing Human Hearts
Published in Journal of the American College of Cardiology (04-02-2014)“…[...]little is known about the regulation of the V1A-R in the failing heart. [...]the present study was undertaken to evaluate the expression of the V1A-R in…”
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Initial Right Ventricular Dysfunction Severity Identifies Severe Peripartum Cardiomyopathy Phenotype With Worse Early and Overall Outcomes: A 24‐Year Cohort Study
Published in Journal of the American Heart Association (01-05-2018)“…Background Outcomes in peripartum cardiomyopathy (PPCM) vary. We sought to determine whether severity of left or right ventricular dysfunction (RVD) at PPCM…”
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6
COVID-19 and Cardiovascular Disease: From Bench to Bedside
Published in Circulation research (16-04-2021)“…A pandemic of historic impact, coronavirus disease 2019 (COVID-19) has potential consequences on the cardiovascular health of millions of people who survive…”
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Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics
Published in Pharmacology & therapeutics (Oxford) (01-06-2009)“…Cyclic guanosine 3',5'-monophosphate (cGMP) mediates a wide spectrum of physiologic processes in multiple cell types within the cardiovascular system…”
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Cell-Specific Mechanisms in the Heart of COVID-19 Patients
Published in Circulation research (12-05-2023)“…From the onset of the pandemic, evidence of cardiac involvement in acute COVID-19 abounded. Cardiac presentations ranged from arrhythmias to ischemia,…”
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2013 ACCF/AHA Guideline for the Management of Heart Failure: Executive Summary: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Published in Circulation (15-10-2013)Get full text
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10
Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies
Published in The New England journal of medicine (21-01-2016)“…Peripartum cardiomyopathy shares clinical features with idiopathic dilated cardiomyopathy, a disorder associated with mutations in more than 40 genes. This…”
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2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines
Published in Circulation (15-10-2013)Get full text
Journal Article Conference Proceeding -
12
Cardiac Fibroblast Glycogen Synthase Kinase-3β Regulates Ventricular Remodeling and Dysfunction in Ischemic Heart
Published in Circulation (New York, N.Y.) (29-07-2014)“…Myocardial infarction-induced remodeling includes chamber dilatation, contractile dysfunction, and fibrosis. Of these, fibrosis is the least understood. After…”
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13
How Does COVID-19 Affect the Heart?
Published in Current cardiology reports (01-03-2023)“…Purpose of Review Cardiac consequences occur in both acute COVID-19 and post-acute sequelae of COVID-19 (PASC). Here, we highlight the current understanding…”
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Differential microRNA-21 and microRNA-221 Upregulation in the Biventricular Failing Heart Reveals Distinct Stress Responses of Right Versus Left Ventricular Fibroblasts
Published in Circulation. Heart failure (01-01-2020)“…The failing right ventricle (RV) does not respond like the left ventricle (LV) to guideline-directed medical therapy of heart failure, perhaps due to…”
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United network for organ sharing outcomes after heart transplantation for al compared to ATTR cardiac amyloidosis
Published in Clinical transplantation (01-10-2020)“…Light‐chain (AL) cardiac amyloidosis (CA) has a worse prognosis than transthyretin (ATTR) CA. In this single‐center study, we compared post‐heart transplant…”
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Progression Toward Decompensated Right Ventricular Failure in the Ovine Pulmonary Hypertension Model
Published in ASAIO journal (1992) (01-02-2022)“…Decompensated right ventricular failure (RVF) in patients with pulmonary hypertension (PH) is fatal, with limited treatment options. Novel mechanical…”
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Author Correction: A molecular single-cell lung atlas of lethal COVID-19
Published in Nature (London) (28-10-2021)Get full text
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2013 ACCF/AHA Guideline for the Management of Heart Failure: Executive Summary
Published in Journal of the American College of Cardiology (15-10-2013)“…An organized and directed approach to a thorough review of evidence has resulted in the production of clinical practice guidelines that assist clinicians in…”
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A Large Animal Model for Pulmonary Hypertension and Right Ventricular Failure: Left Pulmonary Artery Ligation and Progressive Main Pulmonary Artery Banding in Sheep
Published in Journal of visualized experiments (15-07-2021)“…Decompensated right ventricular failure (RVF) in pulmonary hypertension (PH) is fatal, with limited medical treatment options. Developing and testing novel…”
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Chronic β1-adrenergic blockade enhances myocardial β3-adrenergic coupling with nitric oxide-cGMP signaling in a canine model of chronic volume overload: new insight into mechanisms of cardiac benefit with selective β1-blocker therapy
Published in Basic research in cardiology (01-01-2015)“…The β 1 -adrenergic antagonist metoprolol improves cardiac function in animals and patients with chronic heart failure, isolated mitral regurgitation (MR), and…”
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