Search Results - "Trzaskowski, Maciej"
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Causal associations between risk factors and common diseases inferred from GWAS summary data
Published in Nature communications (15-01-2018)“…Health risk factors such as body mass index (BMI) and serum cholesterol are associated with many common diseases. It often remains unclear whether the risk…”
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Attention-Deficit/Hyperactivity Disorder Is the Extreme and Impairing Tail of a Continuum
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01-04-2015)“…Family, twin, and adoption studies converge to show that attention-deficit/hyperactivity disorder (ADHD) is a familial disorder influenced by genetic factors…”
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3
Study on Saccharide–Glucose Receptor Interactions with the Use of Surface Plasmon Resonance
Published in International journal of molecular sciences (01-11-2023)“…The aim of this study was to investigate the process of attachment of saccharide particles differing in degree of complexity to cell receptors responsible for…”
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4
high heritability of educational achievement reflects many genetically influenced traits, not just intelligence
Published in Proceedings of the National Academy of Sciences - PNAS (21-10-2014)“…Significance Differences among children in educational achievement are highly heritable from the early school years until the end of compulsory education at…”
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5
Verifying explainability of a deep learning tissue classifier trained on RNA-seq data
Published in Scientific reports (29-01-2021)“…For complex machine learning (ML) algorithms to gain widespread acceptance in decision making, we must be able to identify the features driving the…”
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Global genetic differentiation of complex traits shaped by natural selection in humans
Published in Nature communications (14-05-2018)“…There are mean differences in complex traits among global human populations. We hypothesize that part of the phenotypic differentiation is due to natural…”
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Improving genetic prediction by leveraging genetic correlations among human diseases and traits
Published in Nature communications (07-03-2018)“…Genomic prediction has the potential to contribute to precision medicine. However, to date, the utility of such predictors is limited due to low accuracy for…”
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No Genetic Influence for Childhood Behavior Problems From DNA Analysis
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01-10-2013)“…Objective Twin studies of behavior problems in childhood point to substantial genetic influence. It is now possible to estimate genetic influence using DNA…”
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Socioeconomic status (SES) and children's intelligence (IQ): in a UK-representative sample SES moderates the environmental, not genetic, effect on IQ
Published in PloS one (01-02-2012)“…The environment can moderate the effect of genes - a phenomenon called gene-environment (GxE) interaction. Several studies have found that socioeconomic status…”
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Comparative Evaluation of Different Surface Coatings of Fe3O4-Based Magnetic Nano Sorbent for Applications in the Nucleic Acids Extraction
Published in International journal of molecular sciences (09-08-2022)“…Nucleic acid extraction and purification are crucial steps in sample preparation for multiple diagnostic procedures. Routine methodologies of DNA isolation…”
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Physicochemical and Biological Properties of Graphene-Oxide-Coated Metallic Materials
Published in Materials (01-10-2021)“…In this article, we present graphene oxide (produced by a modified Hummers' method) coatings obtained using two different methods: electrophoretic deposition…”
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MicroRNA Delivery by Graphene-Based Complexes into Glioblastoma Cells
Published in Molecules (Basel, Switzerland) (25-09-2021)“…Glioblastoma (GBM) is the most common primary and aggressive tumour in brain cancer. Novel therapies, despite achievements in chemotherapy, radiation and…”
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Discontinuity in the genetic and environmental causes of the intellectual disability spectrum
Published in Proceedings of the National Academy of Sciences - PNAS (26-01-2016)“…Intellectual disability (ID) occurs in almost 3% of newborns. Despite substantial research, a fundamental question about its origin and links to intelligence…”
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Strong genetic influence on a UK nationwide test of educational achievement at the end of compulsory education at age 16
Published in PloS one (11-12-2013)“…We have previously shown that individual differences in educational achievement are highly heritable in the early and middle school years in the UK. The…”
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A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms in Population-Based Paediatric Cohorts
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01-10-2016)“…Abstract Objective To elucidate the influence of common genetic variants on childhood attention-deficit/hyperactivity disorder (ADHD) symptoms, to identify…”
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Exploring Extracellular Vesicles of Probiotic Yeast as Carriers of Biologically Active Molecules Transferred to Human Intestinal Cells
Published in International journal of molecular sciences (01-07-2023)“…Extracellular vesicles (EVs) are nanoparticles containing various bioactive cargos-e.g., proteins, RNAs, and lipids-that are released into the environment by…”
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Portable Surface Plasmon Resonance Detector for COVID-19 Infection
Published in Sensors (Basel, Switzerland) (01-04-2023)“…Methods based on nucleic acid detection are currently the most commonly used technique in COVID-19 diagnostics. Although generally considered adequate, these…”
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Genetic influence on social outcomes during and after the Soviet era in Estonia
Published in Nature human behaviour (01-04-2018)“…The aetiology of individual differences in educational attainment and occupational status includes genetic as well as environmental factors 1 – 5 and can…”
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Protein-Mediated Transformations of Superparamagnetic Nanoparticles Evidenced by Single-Particle Inductively Coupled Plasma Tandem Mass Spectrometry: A Disaggregation Phenomenon
Published in International journal of molecular sciences (19-01-2022)“…Progress toward translating superparamagnetic iron oxide nanoparticles (SPIONs) with specific diagnostic and therapeutic properties for clinical applications…”
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The Influence of Decontamination Procedures on the Surface of Two Polymeric Liners Used in Prosthodontics
Published in Polymers (11-12-2021)“…Polymeric liners are materials commonly used in prosthodontics to reshape denture surfaces contacting the soft tissues of the oral cavity. The aim of the study…”
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