Search Results - "Trygg, Johan"

LIVECell—A large-scale dataset for label-free live cell segmentation by Edlund, Christoffer, Jackson, Timothy R., Khalid, Nabeel, Bevan, Nicola, Dale, Timothy, Dengel, Andreas, Ahmed, Sheraz, Trygg, Johan, Sjögren, Rickard

“…Light microscopy combined with well-established protocols of two-dimensional cell culture facilitates high-throughput quantitative imaging to study biological…”
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Chemometrics in metabolomics—A review in human disease diagnosis by Madsen, Rasmus, Lundstedt, Torbjörn, Trygg, Johan

“…Metabolomics is a post genomic research field concerned with developing methods for analysis of low molecular weight compounds in biological systems, such as…”
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CV-ANOVA for significance testing of PLS and OPLS® models by Eriksson, Lennart, Trygg, Johan, Wold, Svante

“…This report describes significance testing for PLS and OPLS® (orthogonal PLS) models. The testing is applicable to single‐Y cases and is based on ANOVA of the…”
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Variable influence on projection (VIP) for OPLS models and its applicability in multivariate time series analysis by Galindo-Prieto, Beatriz, Eriksson, Lennart, Trygg, Johan

“…Recently a new parameter to infer variable importance in orthogonal projections to latent structures (OPLS) was presented. Called OPLS-VIP (variable influence…”
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Haralick texture features from apparent diffusion coefficient (ADC) MRI images depend on imaging and pre-processing parameters by Brynolfsson, Patrik, Nilsson, David, Torheim, Turid, Asklund, Thomas, Karlsson, Camilla Thellenberg, Trygg, Johan, Nyholm, Tufve, Garpebring, Anders

“…In recent years, texture analysis of medical images has become increasingly popular in studies investigating diagnosis, classification and treatment response…”
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Multiblock variable influence on orthogonal projections (MB-VIOP) for enhanced interpretation of total, global, local and unique variations in OnPLS models by Galindo-Prieto, Beatriz, Geladi, Paul, Trygg, Johan

“…For multivariate data analysis involving only two input matrices (e.g., X and Y), the previously published methods for variable influence on projection (e.g.,…”
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Visualization of GC/TOF-MS-Based Metabolomics Data for Identification of Biochemically Interesting Compounds Using OPLS Class Models by Wiklund, Susanne, Johansson, Erik, Sjöström, Lina, Mellerowicz, Ewa J, Edlund, Ulf, Shockcor, John P, Gottfries, Johan, Moritz, Thomas, Trygg, Johan

“…Metabolomics studies generate increasingly complex data tables, which are hard to summarize and visualize without appropriate tools. The use of chemometrics…”
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Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance by Rentoft, Matilda, Lindell, Kristoffer, Tran, Phong, Chabes, Anna Lena, Buckland, Robert J., Watt, Danielle L., Marjavaara, Lisette, Nilsson, Anna Karin, Melin, Beatrice, Trygg, Johan, Johansson, Erik, Chabes, Andrei

“…Even small variations in dNTP concentrations decrease DNA replication fidelity, and this observation prompted us to analyze genomic cancer data formutations in…”
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Statistical analysis in metabolic phenotyping by Blaise, Benjamin J., Correia, Gonçalo D. S., Haggart, Gordon A., Surowiec, Izabella, Sands, Caroline, Lewis, Matthew R., Pearce, Jake T. M., Trygg, Johan, Nicholson, Jeremy K., Holmes, Elaine, Ebbels, Timothy M. D.

“…Metabolic phenotyping is an important tool in translational biomedical research. The advanced analytical technologies commonly used for phenotyping, including…”
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Orthogonal projections to latent structures (O-PLS) by Trygg, Johan, Wold, Svante

“…A generic preprocessing method for multivariate data, called orthogonal projections to latent structures (O‐PLS), is described. O‐PLS removes variation from X…”
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Near-infrared hyperspectral image analysis for monitoring the cheese-ripening process by Alinaghi, Masoumeh, Nilsson, David, Singh, Nikita, Höjer, Annika, Saedén, Karin Hallin, Trygg, Johan

“…Ripening is the most crucial process step in cheese manufacturing and constitutes multiple biochemical alterations that describe the final cheese quality and…”
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Metabolite and Lipid Profiling of Biobank Plasma Samples Collected Prior to Onset of Rheumatoid Arthritis by Surowiec, Izabella, Ärlestig, Lisbeth, Rantapää-Dahlqvist, Solbritt, Trygg, Johan

“…The early diagnosis of rheumatoid arthritis (RA) is desirable to install treatment to prevent disease progression and joint destruction. Autoantibodies and…”
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Metabolic Profiling of Systemic Lupus Erythematosus and Comparison with Primary Sjögren's Syndrome and Systemic Sclerosis by Bengtsson, Anders A, Trygg, Johan, Wuttge, Dirk M, Sturfelt, Gunnar, Theander, Elke, Donten, Magdalena, Moritz, Thomas, Sennbro, Carl-Johan, Torell, Frida, Lood, Christian, Surowiec, Izabella, Rännar, Stefan, Lundstedt, Torbjörn

“…Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease which can affect most organ systems including skin, joints and the kidney…”
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A chemometrics toolbox based on projections and latent variables by Eriksson, Lennart, Trygg, Johan, Wold, Svante

“…A personal view is given about the gradual development of projection methods—also called bilinear, latent variable, and more—and their use in chemometrics. We…”
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OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification by Bylesjö, Max, Rantalainen, Mattias, Cloarec, Olivier, Nicholson, Jeremy K., Holmes, Elaine, Trygg, Johan

“…The characteristics of the OPLS method have been investigated for the purpose of discriminant analysis (OPLS‐DA). We demonstrate how class‐orthogonal variation…”
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O2-PLS for qualitative and quantitative analysis in multivariate calibration by Trygg, Johan

“…In this paper the O‐PLS method [1] has been modified to further improve its interpretational functionality to give (a) estimates of the pure constituent…”
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Cell‐specific chemotyping and multivariate imaging by combined FT‐IR microspectroscopy and orthogonal projections to latent structures (OPLS) analysis reveals the chemical landscape of secondary xylem by Gorzsás, András, Stenlund, Hans, Persson, Per, Trygg, Johan, Sundberg, Björn

“…Summary Fourier‐transform infrared (FT‐IR) spectroscopy combined with microscopy enables chemical information to be acquired from native plant cell walls with…”
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Data integration in plant biology: the O2PLS method for combined modeling of transcript and metabolite data by Bylesjö, Max, Eriksson, Daniel, Kusano, Miyako, Moritz, Thomas, Trygg, Johan

“…The technological advances in the instrumentation employed in life sciences have enabled the collection of a virtually unlimited quantity of data from multiple…”
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Metabolic profiling of zebrafish embryo development from blastula period to early larval stages by Dhillon, Sundeep S, Torell, Frida, Donten, Magdalena, Lundstedt-Enkel, Katrin, Bennett, Kate, Rännar, Stefan, Trygg, Johan, Lundstedt, Torbjörn

“…The zebrafish embryo is a popular model for drug screening, disease modelling and molecular genetics. In this study, samples were obtained from zebrafish at…”
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ADC texture—An imaging biomarker for high‐grade glioma? by Brynolfsson, Patrik, Nilsson, David, Henriksson, Roger, Hauksson, Jón, Karlsson, Mikael, Garpebring, Anders, Birgander, Richard, Trygg, Johan, Nyholm, Tufve, Asklund, Thomas

“…Purpose: Survival for high‐grade gliomas is poor, at least partly explained by intratumoral heterogeneity contributing to treatment resistance. Radiological…”
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