Search Results - "Truter, S"

Pain assessment in chronic pancreatitis: A comparative review of methods by Teo, K, Johnson, M.H, Truter, S, Pandanaboyana, S, Windsor, J.A

“…Abstract Background Patients with chronic pancreatitis (CP) frequently report chronic abdominal pain that adversely impacts their quality of life. Assessment…”
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PhRMA Survey of Pharmacogenomic and Pharmacodynamic Evaluations: What Next? by Grecco, N, Cohen, N, Warner, A W, Lopez-Correa, C, Truter, S L, Snapir, A, Piccoli, S P, Wang, D, Westelinck, A, Hinman, L, Franc, M A

“…Interindividual variation in pharmacodynamic (PD) response to drugs is an ongoing area of research for drugs in clinical development, pre‐ and postapproval. To…”
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Transforming growth factor-beta stimulates alpha 2(I) collagen gene expression through a cis-acting element that contains an Sp1-binding site by Inagaki, Y, Truter, S, Ramirez, F

“…Transforming growth factor-beta 1 (TGF-beta) is a strong and rapid inducer of several genes coding for extracellular matrix components, such as type I…”
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Identification of an upstream regulatory region essential for cell type-specific transcription of the pro-alpha 2(V) collagen gene (COL5A2) by Truter, S, Di Liberto, M, Inagaki, Y, Ramirez, F

“…The transcriptional features of the human alpha 2(V) collagen gene (COL5A2) were examined by transfection experiments coupled to various DNA binding assays…”
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Melanin-Concentrating Hormone 1 Receptor-Deficient Mice are Lean, Hyperactive, and Hyperphagic and Have Altered Metabolism by Marsh, Donald J., Weingarth, Drew T., Novi, Dawn E., Chen, Howard Y., Trumbauer, Myrna E., Chen, Airu S., Guan, Xiao-Ming, Jiang, Michael M., Feng, Yue, Camacho, Ramon E., Shen, Zhu, Frazier, Easter G., Yu, Hong, Metzger, Joseph M., Kuca, Stephanie J., Shearman, Lauren P., Gopal-Truter, Shobhna, MacNeil, Douglas J., Strack, Alison M., MacIntyre, D. Euan, Lex H. T. Van der Ploeg, Qian, Su

“…Melanin-concentrating hormone (MCH) is a cyclic 19-aa hypothalamic neuropeptide derived from a larger prohormone precursor of MCH (Pmch), which also encodes…”
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Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass by Van der Ploeg, Lex H.T, Chen, Airu S, Marsh, Donald J, Trumbauer, Myrna E, Frazier, Easter G, Guan, Xiao-Ming, Yu, Hong, Rosenblum, Charles I, Vongs, Aurawan, Feng, Yue, Cao, Linhai, Metzger, Joseph M, Strack, Alison M, Camacho, Ramon E, Mellin, Theodore N, Nunes, Christian N, Min, William, Fisher, Jill, Gopal-Truter, Shobhna, MacIntyre, D. Euan, Chen, Howard Y

“…Genetic and pharmacological studies have defined a role for the melanocortin-4 receptor (Mc4r) in the regulation of energy homeostasis. The physiological…”
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Neither Agouti-Related Protein nor Neuropeptide Y Is Critically Required for the Regulation of Energy Homeostasis in Mice by Qian, Su, Chen, Howard, Weingarth, Drew, Trumbauer, Myrna E., Novi, Dawn E., Guan, Xiaoming, Yu, Hong, Shen, Zhu, Feng, Yue, Frazier, Easter, Chen, Airu, Camacho, Ramon E., Shearman, Lauren P., Gopal-Truter, Shobhna, MacNeil, Douglas J., Van der Ploeg, Lex H. T., Marsh, Donald J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Transforming growth factor-β stimulates α2(I) collagen gene expression through a cis-acting element that contains an Sp1-binding site by INAGAKI, Y, TRUTER, S, RAMIREZ, F

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Myocardial fibrosis in chronic aortic regurgitation: Molecular and cellular responses to volume overload by BORER, Jeffrey S, TRUTER, Sharada, HERROLD, Edmund M, FALCONE, Domenick J, PENA, Magda, CARTER, John N, DUMLAO, Themy F, LEE, Jennifer A, SUPINO, Phyllis G

“…Myocardial fibrosis is common in patients with chronic aortic regurgitation (AR). Experimentally, fibrosis with disproportionate noncollagen extracellular…”
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Somatostatin Receptor Subtype 5 Regulates Insulin Secretion and Glucose Homeostasis by Strowski, Mathias Z, Kohler, Martin, Chen, Howard Y, Trumbauer, Myrna E, Li, Zhihua, Szalkowski, Deborah, Gopal-Truter, Shobhna, Fisher, Jill K, Schaeffer, James M, Blake, Allan D, Zhang, Bei B, Wilkinson, Hilary A

“…Somatostatin (SRIF) regulates pancreatic insulin and glucagon secretion. In the present study we describe the generation of SRIF receptor subtype 5 knockout…”
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Protected regions in the chicken alpha 2(1) procollagen promoter in differentiated tissues by Truter, S L, Parker, M I

“…The higher ordered structure of the chicken alpha 2(1) procollagen gene was analyzed in chromatin isolated from expressing (lung) and nonexpressing…”
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The selection of medical students by Truter, S R

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Role of the melanocortin-4 receptor in metabolic rate and food intake in mice by CHEN, A. S, METZGER, J. M, CAMACHO, R. E, STRACK, A. M, MELLIN, T. N, MACINTYRE, D. E, CHEN, H. Y, VAN DER PLOEG, L. H. T, TRUMBAUER, M. E, GUAN, X.-M, HONG YU, FRAZIER, E. G, MARSH, D. J, FORREST, M. J, GOPAL-TRUTER, S, FISHER, J

“…We evaluated the role of the melanocortin-4 receptor (MC-4R) in the control of metabolic rate and food intake in mice. Intraperitoneal administration of the…”
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Overlapping pathways mediate the opposing actions of tumor necrosis factor-alpha and transforming growth factor-beta on alpha 2(I) collagen gene transcription by Inagaki, Y, Truter, S, Tanaka, S, Di Liberto, M, Ramirez, F

“…Transforming growth factor-beta (TGF-beta) and tumor necrosis factor-alpha (TNF-alpha) are multifunctional peptides intimately involved in the process of…”
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Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl :protein transferase inhibitor by OMER, C. A, ZUNXUAN CHEN, DAVIDE, J. P, ELLIS, M. S, GIBBS, J. B, GREENBERG, I, HAMILTON, K, KOBLAN, K. S, KRAL, A. M, DONGMING LIU, LOBELL, R. B, MILLER, P. J, DIEHL, R. E, MOSSER, S. D, O'NEILL, T. J, RANDS, E, SCHABER, M. D, SENDERAK, E. T, OLIFF, A, KOHL, N. E, CONNER, M. W, CHEN, H. Y, TRUMBAUER, M. E, GOPAL-TRUTER, S, SEEBURGER, G, BHIMNATHWALA, H, ABRAMS, M. T

“…For Ras oncoproteins to transform mammalian cells, they must be posttranslationally modified with a farnesyl group in a reaction catalyzed by the enzyme…”
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Regulation of the alpha 2(I) collagen gene transcription in fat-storing cells derived from a cirrhotic liver by Inagaki, Y, Truter, S, Greenwel, P, Rojkind, M, Unoura, M, Kobayashi, K, Ramirez, F

“…Fat-storing cells (FSC) are the main producers of type I collagen in both normal and fibrotic livers. In order to elucidate the molecular mechanisms…”
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Activation of Pro alpha 2(I) Collagen Promoter during Hepatic Fibrogenesis in Transgenic Mice by Inagaki, Y, Truter, S, Bou-Gharios, G, Garrett, LA, De crombrugghe, B, Nemoto, T, Greenwel, P

“…We previously identified the promoter sequence that is essential for basal and TGF- beta -stimulated transcription of alpha 2(I) collagen gene (COL1A2). In the…”
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Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact by Goodsaid, Federico M, Amur, Shashi, Aubrecht, Jiri, Burczynski, Michael E, Carl, Kevin, Catalano, Jennifer, Charlab, Rosane, Close, Sandra, Cornu-Artis, Catherine, Essioux, Laurent, Fornace, Albert J, Hinman, Lois, Hong, Huixiao, Hunt, Ian, Jacobson-Kram, David, Jawaid, Ansar, Laurie, David, Lesko, Lawrence, Li, Heng-Hong, Lindpaintner, Klaus, Mayne, James, Morrow, Peter, Papaluca-Amati, Marisa, Robison, Timothy W, Roth, John, Schuppe-Koistinen, Ina, Shi, Leming, Spleiss, Olivia, Tong, Weida, Truter, Sharada L, Vonderscher, Jacky, Westelinck, Agnes, Zhang, Li, Zineh, Issam

“…Biomarker strategies are increasingly being applied in drug development to address the challenges posed by heterogeneity in the underlying mechanisms of…”
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Structural and functional analysis of the promoter of the human alpha 1(XI) collagen gene by Yoshioka, H, Greenwel, P, Inoguchi, K, Truter, S, Inagaki, Y, Ninomiya, Y, Ramirez, F

“…In order to eventually elucidate the mechanisms regulating alpha 1(XI) collagen expression in cartilaginous and non-cartilaginous tissues, we performed an…”
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Activation of Proalpha2(I) collagen promoter during hepatic fibrogenesis in transgenic mice by Inagaki, Y, Truter, S, Bou-Gharios, G, Garrett, L A, de Crombrugghe, B, Nemoto, T, Greenwel, P

“…We previously identified the promoter sequence that is essential for basal and TGF-beta-stimulated transcription of alpha2(I) collagen gene (COL1A2). In the…”
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