Search Results - "Trushkov, Igor V"
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Donor-Acceptor Cyclopropanes in the Synthesis of Carbocycles
Published in Chemical record (01-11-2019)“…Donor-acceptor cyclopropanes not only participate in a broad range of ring openings with nucleophiles, electrophiles, radical and red-ox agents, but also are…”
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Furan's Gambit: Electrophile-Attack-Triggered Sacrifice of Furan Rings for the Intramolecular Construction of Azaheterocycles
Published in European journal of organic chemistry (01-05-2015)“…This review summarizes the results of recent investigations of intramolecular furan ring‐opening–azaheterocycle ring‐closing reactions induced by acid or…”
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3
Expanding Stereoelectronic Limits of endo-tet Cyclizations: Synthesis of Benz[b]azepines from Donor–Acceptor Cyclopropanes
Published in Journal of the American Chemical Society (01-09-2021)“…The importance of intramolecular constraints in cyclic transition-state geometries is especially pronounced in n-endo-tet cyclizations, where the usual…”
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Expanding the Reactivity of Donor–Acceptor Cyclopropanes: Synthesis of Benzannulated Five-Membered Heterocycles via Intramolecular Attack of a Pendant Nucleophilic Group
Published in Organic letters (21-12-2018)“…Lewis-acid-induced domino transformations of donor–acceptor cyclopropanes, possessing a nucleophilic center embedded in a donor group, into functionalized…”
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5
Recent advances in ring-forming reactions of donor–acceptor cyclopropanes
Published in Mendeleev communications (01-11-2011)“…Owing to the relative ease of ring-opening under a variety of conditions, donor–acceptor cyclopropanes serve as synthetic building blocks for construction of…”
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Synthesis of 1,5-Substituted Pyrrolidin-2-ones from Donor-Acceptor Cyclopropanes and Anilines/Benzylamines
Published in Molecules (Basel, Switzerland) (02-12-2022)“…We developed a straightforward synthetic route to pharmacologically important 1,5-substituted pyrrolidin-2-ones from donor-acceptor cyclopropanes bearing an…”
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7
Transformation of 3-(Furan-2-yl)-1,3-di(het)arylpropan-1-ones to Prop-2-en-1-ones via Oxidative Furan Dearomatization/2-Ene-1,4,7-triones Cyclization
Published in Molecules (Basel, Switzerland) (30-04-2021)“…The approach to 3-(furan-2-yl)-1,3-di(het)arylprop-2-en-1-ones based on the oxidative dearomatization of 3-(furan-2-yl)-1,3-di(het)arylpropan-1-ones followed…”
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8
A Simple Route to Polysubstituted Indoles Exploiting Azide Induced Furan Ring Opening
Published in Organic letters (15-08-2014)“…A straightforward, efficient indole synthesis based on thermolysis of 2-(2-azidobenzyl)furans with attack of the formed nitrene moiety onto the ipso position…”
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9
(3 + 3)-Cyclodimerization of Donor–Acceptor Cyclopropanes. Three Routes to Six-Membered Rings
Published in Journal of organic chemistry (04-11-2011)“…The ability of donor–acceptor cyclopropanes to (3 + 3)-cyclodimerize is disclosed. It has been found that Lewis acid-induced transformations of…”
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10
Synthesis of (Het)aryl 2-(2-hydroxyaryl)cyclopropyl Ketones
Published in Molecules (Basel, Switzerland) (05-12-2020)“…A simple general method for the synthesis of 1-acyl-2-( -hydroxyaryl)cyclopropanes, which belong to the donor-acceptor cyclopropane family, has been developed…”
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11
Donor-Acceptor Cyclopropanes as Three-Carbon Components in a [4+3] Cycloaddition Reaction with 1,3-Diphenylisobenzofuran
Published in Angewandte Chemie (International ed.) (01-01-2008)“…Dienophiles with a difference: 2‐Aryl 1,1‐bis(alkoxycarbonyl) cyclopropanes undergo the title reaction under the catalysis of ytterbium triflate (Yb(OTf)3) in…”
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12
Convenient Synthesis of Functionalized Cyclopropa[ c ]coumarin-1a-carboxylates
Published in Molecules (Basel, Switzerland) (24-12-2018)“…A simple method has been developed for the synthesis of cyclopropa[ ]coumarins, which belong to the donor-acceptor cyclopropane family and, therefore, are…”
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13
From biomass to medicines. A simple synthesis of indolo[3,2-c]quinolines, antimalarial alkaloid isocryptolepine, and its derivatives
Published in Organic & biomolecular chemistry (28-09-2012)“…Indolo[3,2-c]quinolines are pharmacologically attractive class of heterocyclic compounds. The method of their synthesis, based on transformation of furfural,…”
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Lewis Acid-Catalyzed Isomerization of 2-Arylcyclopropane-1,1-dicarboxylates: A New Efficient Route to 2-Styrylmalonates
Published in Advanced synthesis & catalysis (17-12-2010)“…A facile efficient approach to the 2‐styrylmalonates via the Lewis acid‐catalyzed isomerization of 2‐arylcyclopropane‐1,1‐dicarboxylates has been developed…”
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Synthesis of 2-[2-(Ethoxymethoxy)phenyl]spiro[cyclopropane-1,2′-indene]-1′,3′-dione
Published in MolBank (01-03-2023)“…An 1,3-indanedione-derived donor–acceptor cyclopropane, bearing the ethoxymethyl-protected phenolic group at the ortho-position of the donor aryl substituent,…”
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Furan ring opening-pyrrole ring closure: a new synthetic route to aryl(heteroaryl)-annulated pyrrolo[1,2-a][1,4]diazepines
Published in Organic & biomolecular chemistry (21-07-2010)“…A method of synthesis of pyrrolo[1,2-a][1,4]benzodiazepines is described. This method is based on the recyclization of N-(furfuryl)anthranilamides under…”
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4b,5,6,9-Tetrahydro-7H-dibenzo[c,e]pyrrolo[1,2-a]azepin-7-one
Published in MolBank (01-06-2019)“…A simple approach to synthesize 4b,5,6,9-tetrahydro-7H-dibenzo[c,e]pyrrolo[1,2-a]azepin- 7-one has been developed, based on a three-step transformation of…”
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18
Ring Opening of Donor-Acceptor Cyclopropanes with the Azide Ion: A Tool for Construction of N-Heterocycles
Published in Chemistry : a European journal (23-03-2015)“…A general method for ring opening of various donor–acceptor cyclopropanes with the azide ion through an SN2‐like reaction has been developed. This highly…”
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(3+3)‐Annulation of Donor–Acceptor Cyclopropanes with Diaziridines
Published in Angewandte Chemie International Edition (06-08-2018)“…The first example of (3+3)‐annulation of two different three‐membered rings is reported herein. Donor‐acceptor cyclopropanes in reaction with diaziridines were…”
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20
Protic Ionic Liquid as Reagent, Catalyst, and Solvent: 1‐Methylimidazolium Thiocyanate
Published in Angewandte Chemie International Edition (29-03-2021)“…We propose a new concept of the triple role of protic ionic liquids with nucleophilic anions: a) a regenerable solvent, b) a Brønsted acid inducing diverse…”
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