Search Results - "Truong, Nga T. H."

GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma by Gargett, Tessa, Ebert, Lisa M, Truong, Nga T H, Kollis, Paris M, Sedivakova, Kristyna, Yu, Wenbo, Yeo, Erica C F, Wittwer, Nicole L, Gliddon, Briony L, Tea, Melinda N, Ormsby, Rebecca, Poonnoose, Santosh, Nowicki, Jake, Vittorio, Orazio, Ziegler, David S, Pitson, Stuart M, Brown, Michael P

“…BackgroundAggressive primary brain tumors such as glioblastoma are uniquely challenging to treat. The intracranial location poses barriers to therapy, and the…”
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Safety and biological outcomes following a phase 1 trial of GD2-specific CAR-T cells in patients with GD2-positive metastatic melanoma and other solid cancers by Gargett, Tessa, Truong, Nga T H, Gardam, Bryan, Yu, Wenbo, Ebert, Lisa M, Johnson, Amy, Yeo, Erica C F, Wittwer, Nicole L, Tapia Rico, Gonzalo, Logan, Jesikah, Sivaloganathan, Purany, Collis, Maria, Ruszkiewicz, Andrew, Brown, Michael P

“…BackgroundChimeric antigen receptor (CAR) T cell therapies specific for the CD19 and B-cell maturation antigen have become an approved standard of care…”
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Effects of Chemotherapy Agents on Circulating Leukocyte Populations: Potential Implications for the Success of CAR-T Cell Therapies by Truong, Nga T. H., Gargett, Tessa, Brown, Michael P., Ebert, Lisa M.

“…Adoptive T-cell therapy using autologous T cells genetically modified to express cancer-specific chimeric antigen receptors (CAR) has emerged as a novel…”
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Endogenous bystander killing mechanisms enhance the activity of novel FAP-specific CAR-T cells against glioblastoma by Yu, Wenbo, Truong, Nga Th, Polara, Ruhi, Gargett, Tessa, Tea, Melinda N, Pitson, Stuart M, Cockshell, Michaelia P, Bonder, Claudine S, Ebert, Lisa M, Brown, Michael P

“…CAR-T cells are being investigated as a novel immunotherapy for glioblastoma, but clinical success has been limited. We recently described fibroblast…”
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