Search Results - "Truong, Jia Q"

A novel small molecule inhibitor of human Drp1 by Rosdah, Ayeshah A., Abbott, Belinda M., Langendorf, Christopher G., Deng, Yali, Truong, Jia Q., Waddell, Helen M. M., Ling, Naomi X. Y., Smiles, William J., Delbridge, Lea M. D., Liu, Guei-Sheung, Oakhill, Jonathan S., Lim, Shiang Y., Holien, Jessica K.

“…Mitochondrial dynamin-related protein 1 (Drp1) is a large GTPase regulator of mitochondrial dynamics and is known to play an important role in numerous…”
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Structural Analysis of the Complex of Human Transthyretin with 3′,5′-Dichlorophenylanthranilic Acid at 1.5 Å Resolution by Cody, Vivian, Truong, Jia Q, Holdsworth, Bruce A, Holien, Jessica K, Richardson, Samantha J, Chalmers, David K, Craik, David J

“…Human transthyretin (hTTR) can form amyloid deposits that accumulate in nerves and organs, disrupting cellular function. Molecules such as tafamidis that bind…”
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Targeting Unconventional Pathways in Pursuit of Novel Antifungals by Nguyen, Stephanie, Truong, Jia Q, Bruning, John B

“…The impact of invasive fungal infections on human health is a serious, but largely overlooked, public health issue. Commonly affecting the immunocompromised…”
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A structural model of the human plasminogen and Aspergillus fumigatus enolase complex by Nguyen, Stephanie, Jovcevski, Blagojce, Truong, Jia Q., Pukala, Tara L., Bruning, John B.

“…The metabolic enzyme, enolase, plays a crucial role in the cytoplasm where it maintains cellular energy production within the process of glycolysis. The main…”
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Simplified heavy‐atom derivatization of protein structures via co‐crystallization with the MAD tetragon tetrabromoterephthalic acid by Truong, Jia Q., Nguyen, Stephanie, Bruning, John B., Shearwin, Keith E.

“…The phase problem is a persistent bottleneck that impedes the structure‐determination pipeline and must be solved to obtain atomic resolution crystal…”
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